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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis

Authors:
Kugler EC, Frost J, Silva V, Plant K, Chhabria K, Chico TJA, Armitage PA
Citation:
Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print
Epub:
Yes
Abstract:
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights into three-dimensional vascular...
Organism or Cell Type:
zebrafish
Citation Extract:
Kugler EC, Frost J, Silva V, Plant K, Chhabria K, Chico TJA, Armitage PA. Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis. Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print.

Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction

Authors:
Wang WQ, Qiu SW, Huang SS, Wang GJ, Han MY, Kang DY, Yuan YY, Gao X, Dai P
Citation:
Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print
Epub:
Not Epub
Abstract:
Background: IFNLR1 has been recently identified to be related to autosomal dominant nonsyndromic sensorineural hearing loss (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang WQ, Qiu SW, Huang SS, Wang GJ, Han MY, Kang DY, Yuan YY, Gao X, Dai P. Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction. Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print.

An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus

Authors:
Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN
Citation:
Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print
Epub:
Yes
Abstract:
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly ultilised to study gene function. MicroRNAs (miRNAs) are...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN. An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus. Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print.

Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos

Authors:
Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL
Citation:
PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print
Epub:
Not Epub
Abstract:
Teleosts live in aquatic habitats, where they encounter ionic and acid-base fluctuations as well as infectious pathogens. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL. Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos. PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print.

A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome

Authors:
Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F
Citation:
Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print
Epub:
Yes
Abstract:
Recessive mutations in the genes encoding the four subunits of the tRNA splicing endonuclease complex (TSEN54, TSEN34, TSEN15,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F. A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print.

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling

Authors:
Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J
Citation:
Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling is fundamentally important for development and adult tissue homeostasis. It is well established that in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J. Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15.

Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor

Authors:
Kwong RW, Kumai Y, Tzaneva V, Azzi E, Hochhold N, Robertson C, Pelster B, Perry SF
Citation:
J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24
Epub:
Not Epub
Abstract:
The present study investigated the potential role of hypoxia-inducible factor (HIF) in calcium homeostasis in developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong RW, Kumai Y, Tzaneva V, Azzi E, Hochhold N, Robertson C, Pelster B, Perry SF. Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor. J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24.

Neuregulin 1 is involved in enteric nervous system development in zebrafish

Authors:
Pu J, Tang S, Tong Q, Wang G, Jia H, Jia Q, Li K, Li D, Yang D, Yang J, Li H, Li S, Mei H
Citation:
J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23
Epub:
Not Epub
Abstract:
Background: Hirschsprung's disease (HD, also known as congenital colon aganglionosis) is a congenital disorder...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pu J, Tang S, Tong Q, Wang G, Jia H, Jia Q, Li K, Li D, Yang D, Yang J, Li H, Li S, Mei H. Neuregulin 1 is involved in enteric nervous system development in zebrafish. J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23.

Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish

Authors:
Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S
Citation:
Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016
Epub:
Not Epub
Abstract:
Myofibrils made up of actin, myosin, and associated proteins generate the contractile force in muscle, and, consequently,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S. Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016.

Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome

Authors:
Eason J, Williams AL, Chawla B, Apsey C, Bohnsack BL
Citation:
Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6
Epub:
Not Epub
Abstract:
Background: Ethanol (ETOH) exposure during pregnancy is associated with craniofacial and neurologic abnormalities, but...
Organism or Cell Type:
zebrafish
Citation Extract:
Eason J, Williams AL, Chawla B, Apsey C, Bohnsack BL. Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome. Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6.

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