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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
IPIP27A cooperates with OCRL to support endocytic traffic in the zebrafish pronephric tubule
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Citation:
Hum Molec Genet. 2021;ddab307 [Epub] doi:10.1093/hmg/ddab307 Epub:
Yes Abstract:
Endocytosis is a fundamentally important process through which material is internalized into cells from the extracellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oltrabella F, Jackson-Crawford A, Yan G, Rixham S, Starborg T, Lowe M. IPIP27A cooperates with OCRL to support endocytic traffic in the zebrafish pronephric tubule. Hum Molec Genet. 2021;ddab307 [Epub] doi:10.1093/hmg/ddab307. |
A dual involvement of Protocadherin-18a in stromal cell development guides the formation of a functional hematopoietic niche
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.19.465038 Epub:
Not Epub Abstract:
Hematopoietic stem and progenitor cells (HSPCs) emerge from the aorta and migrate to the caudal hematopoietic tissue (CHT) of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Touret A-L, Vivier C, Schmidt A, Herbomel P, Murayama E. A dual involvement of Protocadherin-18a in stromal cell development guides the formation of a functional hematopoietic niche. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.19.465038 . |
Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA
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Citation:
Nucl Acids Res. 2021;[Epub]:gkab896. doi:10.1093/nar/gkab896 Epub:
Yes Abstract:
Eukaryotic cells recognize intracellular pathogens through pattern recognition receptors, including sensors of aberrant nucleic... Delivery Method:
Endo-Porter PEG Organism or Cell Type:
cell culture: A549 Citation Extract: Price AM, Steinbock RT, Di C, Hayer KE, Li Y, Herrmann C, Parenti NA, Whelan JN, Weiss SR, Weitzman MD. Adenovirus prevents dsRNA formation by promoting efficient splicing of viral RNA. Nucl Acids Res. 2021;[Epub]:gkab896. doi:10.1093/nar/gkab896. |
Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice
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Citation:
Pharm Res. 2021 Oct 20. doi: 10.1007/s11095-021-03118-5. Online ahead of print Epub:
Yes Abstract:
Purpose: Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs) have shown promise in treating Duchenne muscular... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Mukashyaka MC, Wu CL, Ha K, Zhang J, Wood J, Foley S, Mastis B, Jungels N, Sun H, Shadid M, Harriman S, Hadcock JR. Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice. Pharm Res. 2021 Oct 20. doi: 10.1007/s11095-021-03118-5. Online ahead of print. |
An in vitro system to silence mitochondrial gene expression
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Citation:
Cell. 2021;[Epub ahead of print] doi:10.1016/j.cell.2021.09.033 Epub:
Not Epub Abstract:
The human mitochondrial genome encodes thirteen core subunits of the oxidative phosphorylation system, and defects in... Organism or Cell Type:
cell culture: isolated mitochondria Citation Extract: Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P. An in vitro system to silence mitochondrial gene expression. Cell. 2021;[Epub ahead of print] doi:10.1016/j.cell.2021.09.033. |
The Proapoptotic Gene Bad Regulates Brain Development via P53-Mediated Stress Signals in Zebrafish
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Citation:
Cells. 2021;10(11):2820. doi:10.3390/cells10112820 Epub:
Not Epub Abstract:
Studies have shown that the BH3-only domain Bad regulates brain development via the control of programmed cell death (PCD), but... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hung J-C, Wu J-L, Li H-C, Chiu H-W, Hong J-R. The Proapoptotic Gene Bad Regulates Brain Development via P53-Mediated Stress Signals in Zebrafish. Cells. 2021;10(11):2820. doi:10.3390/cells10112820. |
Genetic landscape of T cells identifies synthetic lethality for T-ALL
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Citation:
Comm Biol. 2021;4(1):1201. doi:10.1038/s42003-021-02694-x Epub:
Not Epub Abstract:
To capture the global gene network regulating the differentiation of immature T cells in an unbiased manner, large-scale... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: O’Meara CP, Guerri L, Lawir D-F, Mateos F, Iconomou M, Iwanami N, Soza-Ried C, Sikora K, Siamishi I, Giorgetti O, Peter S, Schorpp M, Boehm T. Genetic landscape of T cells identifies synthetic lethality for T-ALL. Comm Biol. 2021;4(1):1201. doi:10.1038/s42003-021-02694-x. |
V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking
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Citation:
bioRxiv. 2021;[preprint]. doi:10.1101/2021.10.18.464707 Epub:
Not Epub Abstract:
The mechanism for embryonic dorsal-ventral (DV) symmetry breaking is idiosyncratic to the species, then converges on polarized... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Schatzberg D, Thomas CF, Reidy P, Hadyniak SE, Skidanova V, Lawton ML, Dojer L, Kitchloo S, Zuch DT, Bradham CA. V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking. bioRxiv. 2021;[preprint]. doi:10.1101/2021.10.18.464707. |
Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis
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Citation:
Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7 Epub:
Not Epub Abstract:
Zygotic genome activation (ZGA) initiates regionalized transcription underlying distinct cellular identities. ZGA is dependent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pradhan SJ, Reddy PC, Smutny M, Sharma A, Sako K, Oak MS, Shah R, Pal M, Deshpande O, Dsilva G, Tang Y, Mishra R, Deshpande G, Giraldez AJ, Sonawane M, Heisenberg C-P, Galande S. Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis. Nat Commun. 2021;12(1):6094. doi:10.1038/s41467-021-26234-7. |
NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice
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Citation:
Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print Epub:
Not Epub Abstract:
Maternal obesity is associated with multiple adverse reproductive outcomes, whereas the underlying molecular mechanisms are... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Wang H, Zhu S, Wu X, Liu Y, Ge J, Wang Q, Gu L. NAMPT reduction-induced NAD+ insufficiency contributes to the compromised oocyte quality from obese mice. Aging Cell. 2021 Oct 18:e13496. doi: 10.1111/acel.13496. Online ahead of print. |