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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

A live-imaging protocol to track cell movement in the Xenopus embryo

Authors:
Chuyen A, Daian F, Pasini A, Kodjabachian L
Citation:
STAR Protoc. 2021 Nov 2;2(4):100928. doi: 10.1016/j.xpro.2021.100928. eCollection 2021 Dec 17
Epub:
Not Epub
Abstract:
Tracking individual cell movement during development is challenging, particularly in tissues subjected to major remodeling....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Chuyen A, Daian F, Pasini A, Kodjabachian L. A live-imaging protocol to track cell movement in the Xenopus embryo. STAR Protoc. 2021 Nov 2;2(4):100928. doi: 10.1016/j.xpro.2021.100928. eCollection 2021 Dec 17.

Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death

Authors:
Bhaskar M, Mukherjee S, Basu A
Citation:
mBio. 2021 Nov 16:e0271221. doi: 10.1128/mBio.02712-21. Online ahead of print
Epub:
Yes
Abstract:
Poliomyelitis-like illness is a common clinical manifestation of neurotropic viral infections. Functional loss and death of...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice BALB/c
Citation Extract:
Bhaskar M, Mukherjee S, Basu A. Involvement of RIG-I Pathway in Neurotropic Virus-Induced Acute Flaccid Paralysis and Subsequent Spinal Motor Neuron Death. mBio. 2021 Nov 16:e0271221. doi: 10.1128/mBio.02712-21. Online ahead of print.

Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis

Authors:
Hu SQ, Xu HM, Qian F, Chen CS, Wang X, Liu D, Cheng L
Citation:
Dev Neurobiol. 2021 Nov 14. doi: 10.1002/dneu.22860. Online ahead of print
Epub:
Yes
Abstract:
Interferon regulatory factor-7 (IRF7) is an essential regulator of both innate and adaptive immunity. It is also expressed in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu SQ, Xu HM, Qian F, Chen CS, Wang X, Liu D, Cheng L. Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis. Dev Neurobiol. 2021 Nov 14. doi: 10.1002/dneu.22860. Online ahead of print.

Identification of ACTA2 as a Key Contributor to Venous Malformation

Authors:
Wang S, Zhou Z, Li J, Wang Y, Li H, Lv R, Xu G, Zhang J, Bi J, Huo R
Citation:
Front Cell Dev Biol. 2021;9 [Epub]. doi:10.3389/fcell.2021.755409
Epub:
Not Epub
Abstract:
Objectives: Proteomics and high connotation functional gene screening (HCS) were used to screen key functional genes that play...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang S, Zhou Z, Li J, Wang Y, Li H, Lv R, Xu G, Zhang J, Bi J, Huo R. Identification of ACTA2 as a Key Contributor to Venous Malformation. Front Cell Dev Biol. 2021;9 [Epub]. doi:10.3389/fcell.2021.755409.

Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies

Authors:
Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallieres M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A
Citation:
Blood Cancer Discov. 2022:3(2):103–15. doi:10.1158/2643-3230.BCD-21-0087
Epub:
Not Epub
Abstract:
Downregulation of surface epitopes causes post-immunotherapy relapses in B-lymphoblastic leukemia (B-ALL). Here we demonstrate...
Organism or Cell Type:
cell culture
Citation Extract:
Zheng S, Gillespie E, Naqvi AS, Hayer KE, Ang Z, Torres-Diz M, Quesnel-Vallieres M, Hottman DA, Bagashev A, Chukinas J, Schmidt C, Asnani M, Shraim R, Taylor DM, Rheingold SR, O'Brien MM, Singh N, Lynch KW, Ruella M, Barash Y, Tasian SK, Thomas-Tikhonenko A. Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies. Blood Cancer Discov. 2022:3(2):103–15. doi:10.1158/2643-3230.BCD-21-0087.

Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella

Authors:
Wijesena N, Sun H, Kumburegama S, Wikramanayake AH
Citation:
Dev Biol. 2021 Nov 9:S0012-1606(21)00234-7. doi: 10.1016/j.ydbio.2021.11.002. Online ahead of print
Epub:
Yes
Abstract:
Endomesodermal cell fate specification and archenteron formation during gastrulation are tightly linked developmental processes...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Wijesena N, Sun H, Kumburegama S, Wikramanayake AH. Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella. Dev Biol. 2021 Nov 9:S0012-1606(21)00234-7. doi: 10.1016/j.ydbio.2021.11.002. Online ahead of print.

Nanog regulates primordial germ cell migration through Cxcr4b

Authors:
Sánchez-Sánchez AV, Camp E, Leal-Tassias A, Atkinson SP, Armstrong L, Díaz-Llopis M, Mullor JL
Citation:
Stem Cells. 2010 Sep;28(9):1457-64. doi: 10.1002/stem.469. PMID: 20578184
Epub:
Not Epub
Abstract:
Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct...
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Sánchez-Sánchez AV, Camp E, Leal-Tassias A, Atkinson SP, Armstrong L, Díaz-Llopis M, Mullor JL. Nanog regulates primordial germ cell migration through Cxcr4b. Stem Cells. 2010 Sep;28(9):1457-64. doi: 10.1002/stem.469. PMID: 20578184.

IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential

Authors:
Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B
Citation:
Stem Cells. 2008 Oct;26(10):2666-73. doi: 10.1634/stemcells.2008-0270. Epub 2008 Jul 3
Epub:
Not Epub
Abstract:
Hyperplasia is a major contributor to the increase in adipose tissue mass that is characteristic of obesity. However, the...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse ear mesenchymal stem cells (EMSC)
Citation Extract:
Staszkiewicz J, Gimble JM, Manuel JA, Gawronska-Kozak B. IFATS collection: Stem cell antigen-1-positive ear mesenchymal stem cells display enhanced adipogenic potential. Stem Cells. 2008 Oct;26(10):2666-73. doi: 10.1634/stemcells.2008-0270. Epub 2008 Jul 3.

Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR)

Authors:
Nash D, Arrington CB, Kennedy BJ, Yandell M, Wu W, Zhang W, Ware S, Jorde LB, Gruber PJ, Yost HJ, Bowles NE, Bleyl SB
Citation:
PLoS ONE. 2015;10(6):e0131514. doi:10.1371/journal.pone.0131514
Epub:
Not Epub
Abstract:
Most isolated congenital heart defects are thought to be sporadic and are often ascribed to multifactorial mechanisms with...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nash D, Arrington CB, Kennedy BJ, Yandell M, Wu W, Zhang W, Ware S, Jorde LB, Gruber PJ, Yost HJ, Bowles NE, Bleyl SB. Shared Segment Analysis and Next-Generation Sequencing Implicates the Retinoic Acid Signaling Pathway in Total Anomalous Pulmonary Venous Return (TAPVR). PLoS ONE. 2015;10(6):e0131514. doi:10.1371/journal.pone.0131514.

Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish

Authors:
Anderson EB, Mao Q, Ho RK
Citation:
Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print
Epub:
Yes
Abstract:
The T-box containing family member, TBX5, has been shown to play important functional roles in the pectoral appendages of a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson EB, Mao Q, Ho RK. Tbx5a and Tbx5b paralogues act in combination to control separate vectors of migration in the fin field of zebrafish. Dev Biol. 2021 Oct 28:S0012-1606(21)00231-1. doi: 10.1016/j.ydbio.2021.10.008. Online ahead of print.

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