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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders
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Citation:
Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459 Epub:
Not Epub Abstract:
The blood-brain barrier (BBB) protects the central nervous system (CNS) from harmful blood-borne factors. Although BBB... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Martin M, Vermeiren S, Bostaille N, Eubelen M, Spitzer D, Vermeersch M, Profaci CP, Pozuelo E, Toussay X, Vanhollebeke B. Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders. Science. 2022 Feb 18;375(6582):eabm4459. doi:10.1126/science.abm4459. |
Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator
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Citation:
IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680 Epub:
Not Epub Abstract:
In this study, deoxyribonucleic acid (DNA) hybridization was demonstrated using a suspended silicon photonics micro-ring... Citation Extract: Yousuf S, Kim J, Orozaliev A, Dahlem MS, Song Y-A, Viegas J. Label-Free Detection of Morpholino-DNA Hybridization Using a Silicon Photonics Suspended Slab Micro-Ring Resonator. IEEE Photon J. 2021;14(4):6600809. doi:10.1109/JPHOT.2021.3098680. |
Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells
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Citation:
Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119 Epub:
Yes Abstract:
Tension of the actomyosin cell cortex plays a key role in determining cell-cell contact growth and size. The level of cortical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Slováková J, Sikora M, Arslan FN, Caballero-Mancebo S, Krens SFG, Kaufmann WA, Merrin J, Heisenberg CP. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion in zebrafish germ-layer progenitor cells. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2122030119. doi: 10.1073/pnas.2122030119. |
A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy
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Citation:
J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print Epub:
Not Epub Abstract:
Mutations in the DNAJB6 gene cause limb girdle muscular dystrophy D1 (LGMD D1) and distal myopathy with rimmed vacuoles. With... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu L, Geng H, Lv X, Wang G, Yan C, Zhang D, Lin P. A female carrier of spinal and bulbar muscular atrophy diagnosed with DNAJB6-related distal myopathy. J Hum Genet. 2022 Feb 15. doi: 10.1038/s10038-022-01022-3. Online ahead of print. |
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism
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Citation:
Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290 Epub:
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Zebrafish (ZF; Danio rerio) larvae have become a popular in vivo model in drug metabolism studies. Here, we investigated the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Park YM, Dahlem C, Meyer MR, Kiemer AK, Müller R, Herrmann J. Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism. Molecules. 2022;27(4):1290. doi:10.3390/molecules27041290. |
Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 Epub:
Not Epub Abstract:
Neurofibromatosis type 2 (NF2) is an autosomal dominant condition characterized by the development of multiple tumours of the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary neurofibromatosis cells Citation Extract: Catasus N, Rosas I, Bonache S, Negro A, Plana A, Salvador H, Serra E, Blanco I, Castellanos E. Antisense oligonucleotides targeting exon 11 are able to partially rescue the Neurofibromatosis Type 2 phenotype in vitro. bioRxiv. 2022;[preprint] doi:10.1101/2022.02.11.479859 . |
The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
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Citation:
Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print Epub:
Not Epub Abstract:
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis - a critical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saraswathy VM, Kurup AJ, Sharma P, Polès S, Poulain M, Fürthauer M. The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation. Elife. 2022 Feb 10;11:e71928. doi: 10.7554/eLife.71928. Online ahead of print. |
Planktonic sea urchin larvae change their swimming direction in response to strong photoirradiation
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Citation:
PLoS Genet. 2022;18(2):e1010033. doi:10.1371/journal.pgen.1010033 Epub:
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To survive, organisms need to precisely respond to various environmental factors, such as light and gravity. Among these, light... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Yaguchi S, Taniguchi Y, Suzuki H, Kamata M, Yaguchi J. Planktonic sea urchin larvae change their swimming direction in response to strong photoirradiation. PLoS Genet. 2022;18(2):e1010033. doi:10.1371/journal.pgen.1010033. |
Mcm5 Represses Endodermal Migration through Cxcr4a-itgb1b Cascade Instead of Cell Cycle Control
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Citation:
Biomolecules. 2022;12(2):286. doi:10.3390/biom12020286 Epub:
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Minichromosome maintenance protein 5 (MCM5) is a critical cell cycle regulator; its role in DNA replication is well known, but... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Y, Xia J, Liu M, Chen B, Yang M, Yu X, Ou Y, Li S, Liu X, Feng Y, Su B, Huang S. Mcm5 Represses Endodermal Migration through Cxcr4a-itgb1b Cascade Instead of Cell Cycle Control. Biomolecules. 2022;12(2):286. doi:10.3390/biom12020286. |
Pluripotency factors determine gene expression repertoire at zygotic genome activation
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Citation:
Nat Commun 13, 788 (2022). https://doi.org/10.1038/s41467-022-28434-1 Epub:
Not Epub Abstract:
Awakening of zygotic transcription in animal embryos relies on maternal pioneer transcription factors. The interplay of global... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao M, Veil M, Rosenblatt M, Riesle AJ, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Ulianov SV, Timmer J, Onichtchouk D. Pluripotency factors determine gene expression repertoire at zygotic genome activation. Nat Commun 13, 788 (2022). https://doi.org/10.1038/s41467-022-28434-1. |