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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12153 scientific papers returned from the database with the search filters currently being used below.
There are 12153 scientific papers returned from the database with the search filters currently being used below.
An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus
Citation:
Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print Epub:
Yes Abstract:
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly ultilised to study gene function. MicroRNAs (miRNAs) are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN. An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus. Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print. |
Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos
Citation:
PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print Epub:
Not Epub Abstract:
Teleosts live in aquatic habitats, where they encounter ionic and acid-base fluctuations as well as infectious pathogens. To... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL. Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos. PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print. |
A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome
Citation:
Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print Epub:
Yes Abstract:
Recessive mutations in the genes encoding the four subunits of the tRNA splicing endonuclease complex (TSEN54, TSEN34, TSEN15,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F. A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print. |
Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling
Citation:
Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15 Epub:
Not Epub Abstract:
Hedgehog (Hh) signaling is fundamentally important for development and adult tissue homeostasis. It is well established that in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J. Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15. |
Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor
Citation:
J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24 Epub:
Not Epub Abstract:
The present study investigated the potential role of hypoxia-inducible factor (HIF) in calcium homeostasis in developing... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kwong RW, Kumai Y, Tzaneva V, Azzi E, Hochhold N, Robertson C, Pelster B, Perry SF. Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor. J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24. |
Neuregulin 1 is involved in enteric nervous system development in zebrafish
Citation:
J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23 Epub:
Not Epub Abstract:
Background: Hirschsprung's disease (HD, also known as congenital colon aganglionosis) is a congenital disorder... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pu J, Tang S, Tong Q, Wang G, Jia H, Jia Q, Li K, Li D, Yang D, Yang J, Li H, Li S, Mei H. Neuregulin 1 is involved in enteric nervous system development in zebrafish. J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23. |
Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish
Citation:
Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016 Epub:
Not Epub Abstract:
Myofibrils made up of actin, myosin, and associated proteins generate the contractile force in muscle, and, consequently,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S. Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016. |
Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome
Citation:
Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6 Epub:
Not Epub Abstract:
Background: Ethanol (ETOH) exposure during pregnancy is associated with craniofacial and neurologic abnormalities, but... Organism or Cell Type:
zebrafish Citation Extract: Eason J, Williams AL, Chawla B, Apsey C, Bohnsack BL. Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome. Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6. |
A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans
Citation:
Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24 Epub:
Not Epub Abstract:
Renal agenesis (RA) is one of the more extreme examples of congenital anomalies of the kidney and urinary tract (CAKUT).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR. A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans. Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24. |
The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species
Citation:
Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666 Epub:
Not Epub Abstract:
Neutrophils are essential effector cells of the innate immune system that have recently been recognized as thyroid hormone (TH... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A. The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species. Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666. |