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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling
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Citation:
Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print Epub:
Yes Abstract:
Objectives: To explore the role of DNA methyltransferase 1 (DNMT1) in the development of auditory system using zebrafish as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tang D, Zheng S, Zheng Z, Liu C, Zhang J, Yan R, Wu C, Zuo N, Wu L, Xu H, Liu S, He Y. Dnmt1 is required for the development of auditory organs via cell cycle arrest and Fgf signalling. Cell Prolif. 2022 Mar 29:e13225. doi: 10.1111/cpr.13225. Online ahead of print. |
Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs
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Citation:
J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9 Epub:
Not Epub Abstract:
Background: Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jiang YJ, Fann CS, Fuh JL, Chung MY, Huang HY, Chu KC, Wang YF, Hsu CL, Kao LS, Chen SP, Wang SJ. Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs. J Headache Pain. 2022 Mar 29;23(1):39. doi: 10.1186/s10194-022-01409-9. |
A recessive variant in SIM2 in a child with complex craniofacial anomalies and global developmental delay
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Citation:
Eur J Med Genet. 2022 Apr;65(4):104455. doi: 10.1016/j.ejmg.2022.104455. Epub 2022 Feb 16 Epub:
Not Epub Abstract:
Rare deletions and duplications on the long arm of Chromosome 21 have previously been reported in many patients with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Al-Kurbi AA, Da'as SI, Aamer W, Krishnamoorthy N, Poggiolini I, Abdelrahman D, Elbashir N, Al-Shabeeb Akil A, Glass GE, Fakhro KA. A recessive variant in SIM2 in a child with complex craniofacial anomalies and global developmental delay. Eur J Med Genet. 2022 Apr;65(4):104455. doi: 10.1016/j.ejmg.2022.104455. Epub 2022 Feb 16. |
Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations
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Citation:
Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117 Epub:
Not Epub Abstract:
Cavernous malformations affecting the CNS occur in ∼0.16-0.4% of the general population. The majority (85%) of cavernous... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hong T, Xiao X, Ren J, Cui B, Zong Y, Zou J, Kou Z, Jiang N, Meng G, Zeng G, Shan Y, Wu H, Chen Z, Liang J, Xiao X, Tang J, Wei Y, Ye M, Sun L, Li G, Hu P, Hui R, Zhang H, Wang Y. Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations. Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117. |
miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway
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Citation:
Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133 Epub:
Not Epub Abstract:
Background: Zebrafish miR-731 is orthologous of human miR-425, which has been demonstrated to have cardio-protective roles by a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Huang Y, Wang W-F, Huang C-X, Li X-H, Liu H, Wang H-L. miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway. Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133. |
LAMP2A regulates the loading of proteins into exosomes
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Citation:
Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140 Epub:
Not Epub Abstract:
Exosomes are extracellular vesicles of endosomal origin that are released by practically all cell types across metazoans.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P. LAMP2A regulates the loading of proteins into exosomes. Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140. |
Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries
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Citation:
Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021 Epub:
Not Epub Abstract:
Nitric oxide (NO) relaxes vascular smooth muscle cells (SMCs) and dilates blood vessels by increasing intracellular levels of... Delivery Method:
lipofectamine 2000 Organism or Cell Type:
explants: cerebral arteries Citation Extract: Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E, Earley S. Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries. Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021. |
Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage
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Citation:
Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2119051119. doi: 10.1073/pnas.2119051119. Epub 2022 Mar 25 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) are generated from hemogenic endothelial cells (HECs) in the floor of the dorsal aorta (DA) via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao S, Feng S, Tian Y, Wen Z. Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2119051119. doi: 10.1073/pnas.2119051119. Epub 2022 Mar 25. |
Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish
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Citation:
PLoS Pathog. 2022;18(3):e1010040. doi:10.1371/journal.ppat.1010040 Epub:
Not Epub Abstract:
Invasive aspergillosis is a common opportunistic infection, causing >50% mortality in infected immunocompromised patients.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thrikawala S, Niu M, Keller NP, Rosowski EE. Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish. PLoS Pathog. 2022;18(3):e1010040. doi:10.1371/journal.ppat.1010040. |
Molecularly resolved, label-free nucleic acid sensing at solid-liquid interface using non-ionic DNA analogues
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Citation:
RSC Adv. 2022;12:9263-74. doi:10.1039/D2RA00386D Epub:
Not Epub Abstract:
Nucleic acid-based biosensors, where the capture probe is a nucleic acid, e.g., DNA or its synthetic analogue xeno nucleic acid... Citation Extract: Mana T, Kundu J, Lahiri H, Bera S, Kolay J, Sinha S, Mukhopadhyay R. Molecularly resolved, label-free nucleic acid sensing at solid-liquid interface using non-ionic DNA analogues. RSC Adv. 2022;12:9263-74. doi:10.1039/D2RA00386D. |