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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Wnt11 family dependent morphogenesis during frog gastrulation is marked by the cleavage furrow protein anillin
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Citation:
bioRxiv. 2022;[preprint] doi:/10.1101/2022.01.07.475368 Epub:
Not Epub Abstract:
Wnt11 family proteins are ligands that activate a type of Dishevelled-mediated, non-canonical Wnt signaling pathway. Loss of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Van Itallie ES, Field CM, Mitchison TJ, Kirschner MW. Wnt11 family dependent morphogenesis during frog gastrulation is marked by the cleavage furrow protein anillin. bioRxiv. 2022;[preprint] doi:/10.1101/2022.01.07.475368. |
Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity
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Citation:
Cell Cycle. 2022;[Epub] doi:10.1080/15384101.2021.2023304 Epub:
Yes Abstract:
Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sanchez AC, Thren ED, Iovine MK, Skibbens RV. Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity. Cell Cycle. 2022;[Epub] doi:10.1080/15384101.2021.2023304. |
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-PRC1 axis
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.01.05.474696 Epub:
Not Epub Abstract:
Hematopoiesis changes over life to meet the demands of maturation and aging. Here, we find that the definitive hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang D, Tanaka-Yano M, Meader E, Kinney MA, Morris V, da Rocha EL, Liu N, Orkin SH, North TE, Daley GQ, Rowe RG. Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-PRC1 axis. bioRxiv. 2022;[preprint] doi:10.1101/2022.01.05.474696. |
Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis
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Citation:
Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119 Epub:
Not Epub Abstract:
CFTR gene mutations that result in the introduction of premature termination codons (PTCs) are common in cystic fibrosis (CF).... Delivery Method:
Endo-Porter, osmotic shock Organism or Cell Type:
cell culture: CFF16hBEge-W1282X-SCC:3F2, primary hBE Citation Extract: Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114886119. doi: 10.1073/pnas.2114886119. |
Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans
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Citation:
J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print Epub:
Yes Abstract:
Background: Mutations in the genes that encode the human γ-secretase subunits Presenilin-1, Presenilin Enhancer Protein 2, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hermasch MA, Janning H, Perera RP, Schnabel V, Rostam N, Ramos-Gomes F, Muschalek W, Bennemann A, Alves F, Ralser DJ, Betz RC, Schön MP, Dosch R, Frank J. Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. J Dermatol Sci. 2022 Jan 5:S0923-1811(22)00001-9. doi: 10.1016/j.jdermsci.2022.01.001. Online ahead of print. |
In Vivo Modeling of Zebrafish Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) Expression and its Effect on Pigmentation
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Citation:
International journal of dermatology and venereology 2021;[Epub] doi:10.1097/JD9.0000000000000150 Epub:
Yes Abstract:
Objective: We conducted this study to investigate the role of Zinc Finger MIZ-Type Containing 1 (ZMIZ1) in pigmentation remains... Link:
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microinjection Organism or Cell Type:
zebrafish Citation Extract: Sun Y, Liu T, Mi Z, Wang C, Sun L, Ge K, Sheng D, Liu H, Zhang F. In Vivo Modeling of Zebrafish Zinc Finger, MIZ-Type Containing 1 (ZMIZ1) Expression and its Effect on Pigmentation. International journal of dermatology and venereology 2021;[Epub] doi:10.1097/JD9.0000000000000150. |
Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression
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Citation:
Cell Death Differ. 2022 Jan 1. doi: 10.1038/s41418-021-00915-8. Online ahead of print Epub:
Yes Abstract:
Olig2 is indispensable for motoneuron and oligodendrocyte fate-specification in the pMN domain of embryonic spinal cords, and... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse embryo E14.5 Citation Extract: Bizen N, Bepari AK, Zhou L, Abe M, Sakimura K, Ono K, Takebayashi H. Ddx20, an Olig2 binding factor, governs the survival of neural and oligodendrocyte progenitor cells via proper Mdm2 splicing and p53 suppression. Cell Death Differ. 2022 Jan 1. doi: 10.1038/s41418-021-00915-8. Online ahead of print. |
Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis
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Citation:
Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print Epub:
Yes Abstract:
Zebrafish transgenic lines and light sheet fluorescence microscopy allow in-depth insights into three-dimensional vascular... Organism or Cell Type:
zebrafish Citation Extract: Kugler EC, Frost J, Silva V, Plant K, Chhabria K, Chico TJA, Armitage PA. Zebrafish Vascular Quantification (ZVQ): a tool for quantification of three-dimensional zebrafish cerebrovascular architecture by automated image analysis. Development. 2022 Jan 10:dev.199720. doi: 10.1242/dev.199720. Online ahead of print. |
Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction
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Citation:
Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print Epub:
Not Epub Abstract:
Background: IFNLR1 has been recently identified to be related to autosomal dominant nonsyndromic sensorineural hearing loss (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang WQ, Qiu SW, Huang SS, Wang GJ, Han MY, Kang DY, Yuan YY, Gao X, Dai P. Transcriptome analysis of the early stage ifnlr1-mutant zebrafish indicates the immune response to auditory dysfunction. Gene Expr Patterns. 2021 Dec 27;43:119229. doi: 10.1016/j.gep.2021.119229. Online ahead of print. |
An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus
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Citation:
Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print Epub:
Yes Abstract:
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly ultilised to study gene function. MicroRNAs (miRNAs) are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Godden AM, Antonaci M, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN. An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus. Dev Biol. 2021 Dec 27:S0012-1606(21)00260-8. doi: 10.1016/j.ydbio.2021.12.015. Online ahead of print. |