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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region
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Citation:
Cell Mol Life Sci. 2021 Oct;78(19-20):6669-6687. doi: 10.1007/s00018-021-03939-y. Epub 2021 Sep 23 Epub:
Not Epub Abstract:
The atrioventricular canal (AVC) is the site where key structures responsible for functional division between heart regions are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abu Nahia K, Migdał M, Quinn TA, Poon KL, Łapiński M, Sulej A, Liu J, Mondal SS, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C. Genomic and physiological analyses of the zebrafish atrioventricular canal reveal molecular building blocks of the secondary pacemaker region. Cell Mol Life Sci. 2021 Oct;78(19-20):6669-6687. doi: 10.1007/s00018-021-03939-y. Epub 2021 Sep 23. |
Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control
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Citation:
EMBO J. 2022 Jan 18:e109256. doi: 10.15252/embj.2021109256. Online ahead of print Epub:
Yes Abstract:
The control of mRNA stability plays a central role in regulating gene expression patterns. Recent studies have revealed that... Organism or Cell Type:
zebrafish Citation Extract: Mishima Y, Han P, Ishibashi K, Kimura S, Iwasaki S. Ribosome slowdown triggers codon-mediated mRNA decay independently of ribosome quality control. EMBO J. 2022 Jan 18:e109256. doi: 10.15252/embj.2021109256. Online ahead of print. |
Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function
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Citation:
J Cell Sci. 2022 Jan 24:jcs.258960. doi: 10.1242/jcs.258960. Online ahead of print Epub:
Yes Abstract:
Ciliated epithelia perform essential functions across animal evolution, ranging from locomotion of marine organisms to... Organism or Cell Type:
Xenopus Citation Extract: Nommick A, Boutin C, Rosnet O, Schirmer C, Bazellières E, Thomé V, Loiseau E, Viallat A, Kodjabachian L. Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function. J Cell Sci. 2022 Jan 24:jcs.258960. doi: 10.1242/jcs.258960. Online ahead of print. |
Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE
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Citation:
Blood. 2022 Jan 20;139(3):343-356. doi: 10.1182/blood.2020007885 Epub:
Not Epub Abstract:
In vitro generation and expansion of hematopoietic stem cells (HSCs) holds great promise for the treatment of any ailment that... Organism or Cell Type:
mouse embryo Citation Extract: Fadlullah MZH, Neo WH, Lie-A-Ling M, Thambyrajah R, Patel R, Mevel R, Aksoy I, Do Khoa N, Savatier P, Fontenille L, Baker SM, Rattray M, Kouskoff V, Lacaud G. Murine AGM single-cell profiling identifies a continuum of hemogenic endothelium differentiation marked by ACE. Blood. 2022 Jan 20;139(3):343-356. doi: 10.1182/blood.2020007885. |
Internal Oligoguanidinium Transporter: Mercury-Free Scalable Synthesis, Improvement of Cellular Localization, Endosomal Escape, Mitochondrial Localization, and Conjugation with Antisense Morpholino for NANOG Inhibition to Induce Chemosensitization of Taxo
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Citation:
Bioconjug Chem. 2020 Oct 21;31(10):2367-2382. doi: 10.1021/acs.bioconjchem.0c00444. Epub 2020 Oct 12 Epub:
Not Epub Abstract:
A nontoxic delivery vehicle is essential for the therapeutic applications of antisense phosphorodiamidate morpholino... Delivery Method:
internal guanidinium Organism or Cell Type:
cell culture Citation Extract: Kundu J, Banerjee P, Bose C, Das U, Ghosh U, Sinha S. Internal Oligoguanidinium Transporter: Mercury-Free Scalable Synthesis, Improvement of Cellular Localization, Endosomal Escape, Mitochondrial Localization, and Conjugation with Antisense Morpholino for NANOG Inhibition to Induce Chemosensitization of Taxo. Bioconjug Chem. 2020 Oct 21;31(10):2367-2382. doi: 10.1021/acs.bioconjchem.0c00444. Epub 2020 Oct 12. |
Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate
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Citation:
Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2118817119. doi: 10.1073/pnas.2118817119 Epub:
Yes Abstract:
The protovertebrate Ciona intestinalis type A (sometimes called Ciona robusta) contains a series of sensory cell types... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Chacha PP, Horie R, Kusakabe TG, Sasakura Y, Singh M, Horie T, Levine M. Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2118817119. doi: 10.1073/pnas.2118817119. |
Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1
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Citation:
Genome Med. 2022 Jan 19;14(1):7. doi: 10.1186/s13073-021-01006-6 Epub:
Not Epub Abstract:
Background: Amyotrophic lateral sclerosis (ALS) is a complex, late-onset, neurodegenerative disease with a genetic contribution... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Restuadi R, Steyn FJ, Kabashi E, Ngo ST, Cheng FF, Nabais MF, Thompson MJ, Qi T, Wu Y, Henders AK, Wallace L, Bye CR, Turner BJ, Ziser L, Mathers S, McCombe PA, Needham M, Schultz D, Kiernan MC, van Rheenen W, van den Berg LH, Veldink JH, Ophoff R, Gusev A, Zaitlen N, McRae AF, Henderson RD, Wray NR, Giacomotto J, Garton FC. Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1. Genome Med. 2022 Jan 19;14(1):7. doi: 10.1186/s13073-021-01006-6. |
Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo
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Citation:
Open Biol. 2022 Jan;12(1):210262. doi: 10.1098/rsob.210262. Epub 2022 Jan 19 Epub:
Not Epub Abstract:
Ovothiols are π-methyl-5-thiohistidines produced in great amounts in sea urchin eggs, where they can act as protective agents... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus (sea urchin) Citation Extract: Milito A, Cocurullo M, Columbro A, Nonnis S, Tedeschi G, Castellano I, Arnone MI, Palumbo A. Ovothiol ensures the correct developmental programme of the sea urchin Paracentrotus lividus embryo. Open Biol. 2022 Jan;12(1):210262. doi: 10.1098/rsob.210262. Epub 2022 Jan 19. |
Neuron navigator 3 (NAV3) is required for heart development in zebrafish
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Citation:
Fish Physiol Biochem. 2022 Jan 18. doi: 10.1007/s10695-022-01049-5. Online ahead of print Epub:
Not Epub Abstract:
As a tightly controlled biological process, cardiogenesis requires the specification and migration of a suite of cell types to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lv F, Ge X, Qian P, Lu X, Liu D, Chen C. Neuron navigator 3 (NAV3) is required for heart development in zebrafish. Fish Physiol Biochem. 2022 Jan 18. doi: 10.1007/s10695-022-01049-5. Online ahead of print. |
Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis
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Citation:
PLoS Genet. 2022;18(1):e1010012. doi:10.1371/journal.pgen.1010012 Epub:
Not Epub Abstract:
Ribosomes are essential nanomachines responsible for protein production. Although ribosomes are present in every living cell,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Delhermite J, Tafforeau L, Sharma S, Marchand V, Wacheul L, Lattuca R, Desiderio S, Motorin Y, Bellefroid E, Lafontaine DLJ. Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis. PLoS Genet. 2022;18(1):e1010012. doi:10.1371/journal.pgen.1010012. |