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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy
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Citation:
Cells. 2022;11(8):1285. doi:10.3390/cells11081285 Epub:
Not Epub Abstract:
Hypomyelinating leukodystrophies (HLDs) are a rare group of heterogeneously genetic disorders characterized by persistent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan H, Yang S, Hou Y, Ali S, Escobar A, Gao K, Duan R, Kubisiak T, Wang J, Zhang Y, Xiao J, Jiang Y, Zhang T, Wu Y, Burmeister M, Wang Q, Cuajungco MP, Wang J. Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy. Cells. 2022;11(8):1285. doi:10.3390/cells11081285. |
Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382 Epub:
Not Epub Abstract:
TRIM33 (Tif1-γ) is a transcriptional regulator notably involved in several aspects of hematopoiesis. It is essential for the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Touret A-L, Lancino M, Tauzin M, Capuana L, Pierre C, Herbomel P. Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382. |
The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans
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Citation:
Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8 Epub:
Not Epub Abstract:
CHARGE syndrome is a complex developmental disorder caused by mutations in the chromodomain helicase DNA-binding protein-7 (... Organism or Cell Type:
Xenopus laevis Citation Extract: Jofré DM, Hoffman DK, Cervino AS, Hahn GM, Grundy M, Yun S, Amrit FRG, Stolz DB, Godoy LF, Salvatore E, Rossi FA, Ghazi A, Cirio MC, Yanowitz JL, Hochbaum D. The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8. |
Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord
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Citation:
Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.854556 Epub:
Yes Abstract:
Vessels and nerves are closely associated in anatomy as well as functions. Accumulating evidences have demonstrated that axon-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sheng J, Xu J, Geng K, Liu D. Sema6D Regulates Zebrafish Vascular Patterning and Motor Neuronal Axon Growth in Spinal Cord. Front Mol Neurosci. 2022;15:[Epub] doi:10.3389/fnmol.2022.854556. |
Colorimetric aptasensor for sensitive detection of quinclorac based on exonuclease III-assisted cyclic release of phosphorodiamidate morpholino oligomer mimic enzyme strategy
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Citation:
Anal Chim Acta . 2022 May 15;1207:339815. doi: 10.1016/j.aca.2022.339815. Epub 2022 Apr 8. Epub:
Not Epub Abstract:
Here, a colorimetric aptasensor was constructed for sensitively detecting quinclorac (QNC), a common herbicide. The aptasensor... Citation Extract: Yang L, Ye X, Li X, Huang Z, Chen F, Yang W, Wang Z. Colorimetric aptasensor for sensitive detection of quinclorac based on exonuclease III-assisted cyclic release of phosphorodiamidate morpholino oligomer mimic enzyme strategy. Anal Chim Acta . 2022 May 15;1207:339815. doi: 10.1016/j.aca.2022.339815. Epub 2022 Apr 8. . |
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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Citation:
Cell Rep. 2022 Apr 5;39(1):110587. doi:10.1016/j.celrep.2022.110587 Epub:
Not Epub Abstract:
Hematopoiesis changes over life to meet the demands of maturation and aging. Here, we find that the definitive hematopoietic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang D, Tanaka-Yano M, Meader E, Kinney MA, Morris V, Lummertz da Rocha E, Liu N, Liu T, Zhu Q, Orkin SH, North TE, Daley GQ, Rowe RG. Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis. Cell Rep. 2022 Apr 5;39(1):110587. doi:10.1016/j.celrep.2022.110587. |
Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro
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Citation:
Front Genet. 2022;13:791416. doi:10.3389/fgene.2022.791416 Epub:
Not Epub Abstract:
Oligonucleotides and nucleic acid analogues that alter gene expression are now showing therapeutic promise in human disease.... Delivery Method:
cell bathing or electroporation or Morpholino-DNA heteroduplexes with lipofectamine Organism or Cell Type:
cell culture: fibroblasts, U2OS Citation Extract: Flynn LL, Li R, Pitout IL, Aung-Htut MT, Larcher LM, Cooper JAL, Greer KL, Hubbard A, Griffiths L, Bond CS, Wilton SD, Fox AH, Fletcher S. Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro. Front Genet. 2022;13:791416. doi:10.3389/fgene.2022.791416. |
Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina
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Citation:
bioRXiv. 2021;[preprint] 10.1101/2021.11.03.467208 Epub:
Not Epub Abstract:
Btg3-associated nuclear protein (Banp) was originally identified as a nuclear matrix- associated region (MAR)-binding protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Babu S, Takeuchi Y, Masai I. Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina. bioRXiv. 2021;[preprint] 10.1101/2021.11.03.467208. |
Innervation modulates the functional connectivity between pancreatic endocrine cells
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Citation:
eLife. 2022;11:e64526 doi:10.7554/eLife.64526 Epub:
Not Epub Abstract:
The importance of pancreatic endocrine cell activity modulation by autonomic innervation has been debated. To investigate this... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang YSC, Briant LJB, Raab CA, Mullapudi ST, Maischein H-M, Kawakami K, Stainier DYR. Innervation modulates the functional connectivity between pancreatic endocrine cells. eLife. 2022;11:e64526 doi:10.7554/eLife.64526. |
Nexmifa Regulates Axon Morphogenesis in Motor Neurons in Zebrafish
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Citation:
Front Mol Neurosci. 2022 Mar 31;15:848257. doi: 10.3389/fnmol.2022.848257. eCollection 2022 Epub:
Not Epub Abstract:
Nexmif is mainly expressed in the central nervous system (CNS) and plays important roles in cell migration, cell to cell and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zheng YQ, Suo GH, Liu D, Li HY, Wu YJ, Ni H. Nexmifa Regulates Axon Morphogenesis in Motor Neurons in Zebrafish. Front Mol Neurosci. 2022 Mar 31;15:848257. doi: 10.3389/fnmol.2022.848257. eCollection 2022. |