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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos

Authors:
Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL
Citation:
PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print
Epub:
Not Epub
Abstract:
Teleosts live in aquatic habitats, where they encounter ionic and acid-base fluctuations as well as infectious pathogens. To...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu YF, Liu DW, Li IC, Lin J, Wang CM, Chu KC, Kuo HH, Lin CY, Yih LH, Jiang YJ, Hwang SL. Delta/Jagged-mediated Notch signaling induces the differentiation of agr2-positive epidermal mucous cells in zebrafish embryos. PLoS Genet. 2021 Dec 28;17(12):e1009969. doi: 10.1371/journal.pgen.1009969. Online ahead of print.

A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome

Authors:
Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F
Citation:
Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print
Epub:
Yes
Abstract:
Recessive mutations in the genes encoding the four subunits of the tRNA splicing endonuclease complex (TSEN54, TSEN34, TSEN15,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Canpolat N, Liu D, Atayar E, Saygili S, Kara NS, Westfall TA, Ding Q, Brown BJ, Braun TA, Slusarski D, Oguz KK, Ozluk Y, Tuysuz B, Tastemel Ozturk T, Sever L, Sezerman OU, Topaloglu R, Caliskan S, Attanasio M, Ozaltin F. A splice site mutation in the TSEN2 causes a new syndrome with craniofacial and central nervous system malformations, and atypical hemolytic uremic syndrome. Clin Genet. 2021 Dec 28. doi: 10.1111/cge.14105. Online ahead of print.

Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling

Authors:
Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J
Citation:
Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15
Epub:
Not Epub
Abstract:
Hedgehog (Hh) signaling is fundamentally important for development and adult tissue homeostasis. It is well established that in...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Jin Z, Schwend T, Fu J, Bao Z, Liang J, Zhao H, Mei W, Yang J. Members of the Rusc protein family interact with Sufu and inhibit vertebrate Hedgehog signaling. Development. 2016 Nov 1;143(21):3944-3955. doi: 10.1242/dev.138917. Epub 2016 Sep 15.

Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor

Authors:
Kwong RW, Kumai Y, Tzaneva V, Azzi E, Hochhold N, Robertson C, Pelster B, Perry SF
Citation:
J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24
Epub:
Not Epub
Abstract:
The present study investigated the potential role of hypoxia-inducible factor (HIF) in calcium homeostasis in developing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kwong RW, Kumai Y, Tzaneva V, Azzi E, Hochhold N, Robertson C, Pelster B, Perry SF. Inhibition of calcium uptake during hypoxia in developing zebrafish is mediated by hypoxia-inducible factor. J Exp Biol. 2016 Dec 15;219(Pt 24):3988-3995. doi: 10.1242/jeb.148700. Epub 2016 Oct 24.

Neuregulin 1 is involved in enteric nervous system development in zebrafish

Authors:
Pu J, Tang S, Tong Q, Wang G, Jia H, Jia Q, Li K, Li D, Yang D, Yang J, Li H, Li S, Mei H
Citation:
J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23
Epub:
Not Epub
Abstract:
Background: Hirschsprung's disease (HD, also known as congenital colon aganglionosis) is a congenital disorder...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pu J, Tang S, Tong Q, Wang G, Jia H, Jia Q, Li K, Li D, Yang D, Yang J, Li H, Li S, Mei H. Neuregulin 1 is involved in enteric nervous system development in zebrafish. J Pediatr Surg. 2017 Jul;52(7):1182-1187. doi: 10.1016/j.jpedsurg.2017.01.005. Epub 2017 Jan 23.

Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish

Authors:
Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S
Citation:
Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016
Epub:
Not Epub
Abstract:
Myofibrils made up of actin, myosin, and associated proteins generate the contractile force in muscle, and, consequently,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dash SN, Narumanchi S, Paavola J, Perttunen S, Wang H, Lakkisto P, Tikkanen I, Lehtonen S. Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H1085-H1095. doi: 10.1152/ajpheart.00394.2016.

Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome

Authors:
Eason J, Williams AL, Chawla B, Apsey C, Bohnsack BL
Citation:
Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6
Epub:
Not Epub
Abstract:
Background: Ethanol (ETOH) exposure during pregnancy is associated with craniofacial and neurologic abnormalities, but...
Organism or Cell Type:
zebrafish
Citation Extract:
Eason J, Williams AL, Chawla B, Apsey C, Bohnsack BL. Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome. Birth Defects Res. 2017 Sep 1;109(15):1212-1227. doi: 10.1002/bdr2.1069. Epub 2017 Jul 6.

A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans

Authors:
Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR
Citation:
Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24
Epub:
Not Epub
Abstract:
Renal agenesis (RA) is one of the more extreme examples of congenital anomalies of the kidney and urinary tract (CAKUT)....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brophy PD, Rasmussen M, Parida M, Bonde G, Darbro BW, Hong X, Clarke JC, Peterson KA, Denegre J, Schneider M, Sussman CR, Sunde L, Lildballe DL, Hertz JM, Cornell RA, Murray SA, Manak JR. A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans. Genetics. 2017 Sep;207(1):215-228. doi: 10.1534/genetics.117.1125. Epub 2017 Jul 24.

The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species

Authors:
van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A
Citation:
Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666
Epub:
Not Epub
Abstract:
Neutrophils are essential effector cells of the innate immune system that have recently been recognized as thyroid hormone (TH...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van der Spek AH, Jim KK, Karaczyn A, van Beeren HC, Ackermans MT, Darras VM, Vandenbroucke-Grauls CMJE, Hernandez A, Brouwer MC, Fliers E, van de Beek D, Boelen A. The Thyroid Hormone Inactivating Type 3 Deiodinase Is Essential for Optimal Neutrophil Function: Observations From Three Species. Endocrinology. 2018 Feb 1;159(2):826-835. doi: 10.1210/en.2017-00666.

Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis

Authors:
Goto T, Ito Y, Michiue T
Citation:
Dev Growth Differ. 2018 May;60(4):226-238. doi: 10.1111/dgd.12432. Epub 2018 Apr 26
Epub:
Not Epub
Abstract:
Several chemokine molecules control cell movements during early morphogenesis. However, it is unclear whether chemokine...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Goto T, Ito Y, Michiue T. Roles of Xenopus chemokine ligand CXCLh (XCXCLh) in early embryogenesis. Dev Growth Differ. 2018 May;60(4):226-238. doi: 10.1111/dgd.12432. Epub 2018 Apr 26.

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