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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Role of the Basolateral Na+/H+ Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes)

Authors:
Liu S-T, Horng J-L, Lin L-Y
Citation:
Front Physiol. 2022;13:870967. doi:10.3389/fphys.2022.870967
Epub:
Not Epub
Abstract:
Ionocytes in the skin and gills of seawater (SW) fishes are responsible for acid-base regulation and salt secretion. Na+/H+...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (Medaka)
Citation Extract:
Liu S-T, Horng J-L, Lin L-Y. Role of the Basolateral Na+/H+ Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes). Front Physiol. 2022;13:870967. doi:10.3389/fphys.2022.870967.

Disc and actin-associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia

Authors:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR
Citation:
PLoS Pathog. 2022 Mar 25;18(3):e1010433. doi: 10.1371/journal.ppat.1010433. Online ahead of print
Epub:
Not Epub
Abstract:
The deep-branching eukaryote Giardia lamblia is an extracellular parasite that attaches to the host intestine via a microtubule...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. Disc and actin-associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia. PLoS Pathog. 2022 Mar 25;18(3):e1010433. doi: 10.1371/journal.ppat.1010433. Online ahead of print.

From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergence

Authors:
Kotov A, Alkobtawi M, Seal S, Kappes V, Ruiz SM, Arbes H, Harland R, Peshkin L, Monsoro-Burq AH
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.23.485460
Epub:
Not Epub
Abstract:
Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kotov A, Alkobtawi M, Seal S, Kappes V, Ruiz SM, Arbes H, Harland R, Peshkin L, Monsoro-Burq AH. From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergence. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.23.485460.

Dual-Specificity Phosphatase 14 Regulates Zebrafish Hair Cell Formation Through Activation of p38 Signaling Pathway

Authors:
Wei G, Zhang X, Cai C, Sheng J, Xu M, Wang C, Gu Q, Guo C, Chen F, Liu D, Qian F
Citation:
Front Cell Neurosci. 2022;16:840143. doi:10.3389/fncel.2022.840143
Epub:
Not Epub
Abstract:
Most cases of acquired hearing loss are due to degeneration and subsequent loss of cochlear hair cells. Whereas mammalian hair...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wei G, Zhang X, Cai C, Sheng J, Xu M, Wang C, Gu Q, Guo C, Chen F, Liu D, Qian F. Dual-Specificity Phosphatase 14 Regulates Zebrafish Hair Cell Formation Through Activation of p38 Signaling Pathway. Front Cell Neurosci. 2022;16:840143. doi:10.3389/fncel.2022.840143.

Gold Nanoparticles Conjugated Dna-Tiles for Simultaneous Delivery of Morpholino Antisense Oligonucleotides and Doxorubicin

Authors:
Tunc CU, Çulha M
Citation:
2022. SSRN;JDDST-D-22-00401:[preprint] doi:10.2139/ssrn.4048799
Epub:
Not Epub
Abstract:
Current therapies have limited treatment effect on cancer. Combinational delivery of multiple therapeutics has been commonly...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: breast cancer
Citation Extract:
Tunc CU, Çulha M. Gold Nanoparticles Conjugated Dna-Tiles for Simultaneous Delivery of Morpholino Antisense Oligonucleotides and Doxorubicin. 2022. SSRN;JDDST-D-22-00401:[preprint] doi:10.2139/ssrn.4048799 .

Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation

Authors:
Ahmed M, Kojima Y, Masai I
Citation:
eLife. 2022;11:e74650 doi:10.7554/eLife.74650
Epub:
Not Epub
Abstract:
In the vertebrate retina, an interplay between retinal ganglion cells (RGCs), amacrine (AC), and bipolar (BP) cells establishes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahmed M, Kojima Y, Masai I. Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation. eLife. 2022;11:e74650 doi:10.7554/eLife.74650.

Functional Characterization of the MYO6 Variant p.E60Q in Non-Syndromic Hearing Loss Patients

Authors:
Alkowari M, Espino-Guarch M, Daas S, Abdelrahman D, Hasan W, Krishnamoorthy N, Sathappan A, Sheehan P, Van Panhuys N, The Qatar Genome Program Research Consortium, Estivill X
Citation:
Int J Mol Sci. 2022;23:3369. doi:10.3390/ijms23063369
Epub:
Not Epub
Abstract:
Hereditary hearing loss (HHL) is a common genetic disorder accounting for at least 60% of pre-lingual deafness in children, of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Alkowari M, Espino-Guarch M, Daas S, Abdelrahman D, Hasan W, Krishnamoorthy N, Sathappan A, Sheehan P, Van Panhuys N, The Qatar Genome Program Research Consortium, Estivill X. Functional Characterization of the MYO6 Variant p.E60Q in Non-Syndromic Hearing Loss Patients. Int J Mol Sci. 2022;23:3369. doi:10.3390/ijms23063369.

Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype

Authors:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H
Citation:
Front Cell Dev Biol. 10:852989. doi:10.3389/fcell.2022.852989
Epub:
Not Epub
Abstract:
Tissue factor (TF) is crucial for embryogenesis, as mice lacking TF are embryonically lethal (E10.5). This lethality may be...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. Front Cell Dev Biol. 10:852989. doi:10.3389/fcell.2022.852989.

Exonization by the Emergence of a Cleavage-Polyadenylation Site

Authors:
Méreau A, Lerivray H, Viet J, Hardy S, Paillard L, Audic Y
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.17.484714
Epub:
Not Epub
Abstract:
Exonization is the evolutionary process of recruitment of new exonic regions from previously intronic regions. It is a major...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Méreau A, Lerivray H, Viet J, Hardy S, Paillard L, Audic Y. Exonization by the Emergence of a Cleavage-Polyadenylation Site. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.17.484714.

Interaction of transcription factors Islet2 and Nr2f1b to control vascular patterning during zebrafish development

Authors:
Wang YS, Huang YS, Chiu CC, Wu TY, Zhou JQ, Liang SR, Tai MH, Wu CY
Citation:
Biochem Biophys Res Commun. 2022 Mar 9;604:123-129. doi: 10.1016/j.bbrc.2022.03.042. Online ahead of print
Epub:
Not Epub
Abstract:
Many regulators controlling arterial identity are well described; however, transcription factors that promote vein identity and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YS, Huang YS, Chiu CC, Wu TY, Zhou JQ, Liang SR, Tai MH, Wu CY. Interaction of transcription factors Islet2 and Nr2f1b to control vascular patterning during zebrafish development. Biochem Biophys Res Commun. 2022 Mar 9;604:123-129. doi: 10.1016/j.bbrc.2022.03.042. Online ahead of print.

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