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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
De Novo ARID1B mutations cause growth delay associated with aberrant Wnt/beta-catenin signaling
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Citation:
Hum Mutat. 2020 May;41(5):1012-1024. doi: 10.1002/humu.23990. Epub 2020 Mar 3 Epub:
Not Epub Abstract:
Haploinsufficiency of ARID1B (AT-rich interaction domain 1B) has been involved in autism spectrum disorder, nonsyndromic and... Organism or Cell Type:
zebrafish Citation Extract: Liu X, Hu G, Ye J, Ye B, Shen N, Tao Y, Zhang X, Fan Y, Liu H, Zhang Z, Fang D, Gu X, Mo X, Yu Y. De Novo ARID1B mutations cause growth delay associated with aberrant Wnt/beta-catenin signaling. Hum Mutat. 2020 May;41(5):1012-1024. doi: 10.1002/humu.23990. Epub 2020 Mar 3. |
TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci
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Citation:
Hum Mol Genet. 2020 Aug 11;29(14):2435-2450. doi: 10.1093/hmg/ddaa120 Epub:
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Dysfunction of the gonadotropin-releasing hormone (GnRH) axis causes a range of reproductive phenotypes resulting from defects... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Davis EE, Balasubramanian R, Kupchinsky ZA, Keefe DL, Plummer L, Khan K, Meczekalski B, Heath KE, Lopez-Gonzalez V, Ballesta-Martinez MJ, Margabanthu G, Price S, Greening J, Brauner R, Valenzuela I, Cusco I, Fernandez-Alvarez P, Wierman ME, Li T, Lage K, Barroso PS, Chan YM, Crowley WF, Katsanis N. TCF12 haploinsufficiency causes autosomal dominant Kallmann syndrome and reveals network-level interactions between causal loci. Hum Mol Genet. 2020 Aug 11;29(14):2435-2450. doi: 10.1093/hmg/ddaa120. |
Copper stress induces zebrafish central neural system myelin defects via WNT/NOTCH-hoxb5b signaling and pou3f1/fam168a/fam168b DNA methylation
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Citation:
Biochim Biophys Acta Gene Regul Mech. 2020 Oct;1863(10):194612. doi: 10.1016/j.bbagrm.2020.194612 Epub:
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Unbalanced copper (Cu) homeostasis is associated with neurological development defects and diseases. However, the molecular... Organism or Cell Type:
zebrafish Citation Extract: Zhang T, Guan P, Liu W, Zhao G, Fang Y, Fu H, Gui JF, Li G, Liu JX. Copper stress induces zebrafish central neural system myelin defects via WNT/NOTCH-hoxb5b signaling and pou3f1/fam168a/fam168b DNA methylation. Biochim Biophys Acta Gene Regul Mech. 2020 Oct;1863(10):194612. doi: 10.1016/j.bbagrm.2020.194612. |
Gsx2 is required for specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neural progenitors in zebrafish
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Citation:
Development. 2020 Oct 9;147(19):dev190603. doi: 10.1242/dev.190603 Epub:
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Neurons in the inferior olivary nuclei (IO neurons) send climbing fibers to Purkinje cells to elicit functions of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Itoh T, Takeuchi M, Sakagami M, Asakawa K, Sumiyama K, Kawakami K, Shimizu T, Hibi M. Gsx2 is required for specification of neurons in the inferior olivary nuclei from Ptf1a-expressing neural progenitors in zebrafish. Development. 2020 Oct 9;147(19):dev190603. doi: 10.1242/dev.190603. |
Functional contribution of DCLKs in sea urchin development
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Citation:
Dev Dyn. 2021 Aug;250(8):1160-1172. doi: 10.1002/dvdy.316. Epub 2021 Mar 4 Epub:
Not Epub Abstract:
Background: Doublecortin-like kinase1 and 2 (DCLKs) are protein Ser/Thr kinases important for neuronal development. More... Organism or Cell Type:
sea urchin Citation Extract: Xu D, Wavreil FDM, Waldron A, Yajima M. Functional contribution of DCLKs in sea urchin development. Dev Dyn. 2021 Aug;250(8):1160-1172. doi: 10.1002/dvdy.316. Epub 2021 Mar 4. |
The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm
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Citation:
Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2018220118. doi: 10.1073/pnas.2018220118 Epub:
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The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koopman CD, De Angelis J, Iyer SP, Verkerk AO, Da Silva J, Berecki G, Jeanes A, Baillie GJ, Paterson S, Uribe V, Ehrlich OV, Robinson SD, Garric L, Petrou S, Simons C, Vetter I, Hogan BM, de Boer TP, Bakkers J, Smith KA. The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2018220118. doi: 10.1073/pnas.2018220118. |
IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish
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Citation:
Gen Comp Endocrinol. 2021 Nov 1;313:113875. doi: 10.1016/j.ygcen.2021.113875. Epub 2021 Aug 2 Epub:
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Insulin-like growth factor 2 mRNA binding protein-2 (IGF2BP2 or IMP2) is a member of a conserved family of RNA binding proteins... Organism or Cell Type:
zebrafish Citation Extract: Li M, Rong X, Lu L, Li Y, Yao K, Ge W, Duan C. IGF-2 mRNA binding protein 2 regulates primordial germ cell development in zebrafish. Gen Comp Endocrinol. 2021 Nov 1;313:113875. doi: 10.1016/j.ygcen.2021.113875. Epub 2021 Aug 2. |
Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton
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Citation:
Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409 Epub:
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The regulated expansion of chondrocytes within growth plates and joints ensures proper skeletal development through adulthood.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Smeeton J, Natarajan N, Naveen Kumar A, Miyashita T, Baddam P, Fabian P, Graf D, Crump JG. Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton. Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409. |
Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos
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Citation:
Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012 Epub:
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The ascidian larval tail contains muscle cells for swimming. Most of these muscle cells differentiate autonomously. The genetic... Organism or Cell Type:
Ascidian Citation Extract: Yu D, Iwamura Y, Satou Y, Oda-Ishii I. Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos. Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012. |
Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011 Epub:
Not Epub Abstract:
Epithelial cell properties are determined by the polarized distribution of membrane lipids, the cytoskeleton, and adhesive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rosa JB, Nassman KY, Sagasti A. Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011. |