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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function
Citation:
Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241 Epub:
Not Epub Abstract:
The suppressor of cytokine signaling (SOCS) proteins play important roles in cytokine and growth factor signaling, where they... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Trengove M, Wyett R, Liongue C, Ward AC. Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function. Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241. |
PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a paediatric muscle-wasting disorder caused by genetic loss of the gene encoding the... Delivery Method:
i.v. injection Organism or Cell Type:
mice, mdx Citation Extract: Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties. bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672. |
Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells
Citation:
Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8 Epub:
Not Epub Abstract:
Apolipoproteins L (ApoLs) are Bcl-2-like proteins expressed under inflammatory conditions in myeloid and endothelial cells. We... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: CD8α+ MutuDCs (dendritic cells) Citation Extract: Uzureau S, Coquerelle C, Vermeiren C, Uzureau P, Van Acker A, Pilotte L, Monteyne D, Acolty V, Vanhollebeke B, Van den Eynde B, Pérez-Morga D, Moser M, Pays E. Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells. Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8. |
The H3.3 chaperone Hira complex orchestrates oocyte developmental competence
Citation:
Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print Epub:
Not Epub Abstract:
Successful reproduction requires an oocyte competent to sustaining early embryo development. By the end of oogenesis, the... Delivery Method:
microinjection Organism or Cell Type:
mouse embryo Citation Extract: Smith R, Susor A, Ming H, Tait J, Conti M, Jiang Z, Lin CJ. The H3.3 chaperone Hira complex orchestrates oocyte developmental competence. Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print. |
Pivotal role of PIM2 kinase in plasmablast generation and plasma cell survival, opening new treatment options in myeloma
Citation:
Blood. 2022 Feb 2:blood.2021014011. doi:10.1182/blood.2021014011. Online ahead of print Epub:
Yes Abstract:
The differentiation of B cells into plasmablasts (PBs) and then plasma cells (PCs) is associated with extensive cell... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: human B cell Citation Extract: Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. Pivotal role of PIM2 kinase in plasmablast generation and plasma cell survival, opening new treatment options in myeloma. Blood. 2022 Feb 2:blood.2021014011. doi:10.1182/blood.2021014011. Online ahead of print. |
Chordacentrum mineralization is delayed in zebrafish betaglycan-null mutants
Citation:
Dev Dyn. 2022 Jan;251(1):213-225. doi: 10.1002/dvdy.393. Epub 2021 Jul 17 Epub:
Not Epub Abstract:
Background: The Transforming Growth Factor β (TGFβ) family is a group of related proteins that signal through a type I and type... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Molina-Villa T, Ramírez-Vidal L, Mendoza V, Escalante-Alcalde D, López-Casillas F. Chordacentrum mineralization is delayed in zebrafish betaglycan-null mutants. Dev Dyn. 2022 Jan;251(1):213-225. doi: 10.1002/dvdy.393. Epub 2021 Jul 17. |
Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition
Citation:
Sci Adv. 2022;8(5):eabj3967 doi:10.1126/sciadv.abj3967 Epub:
Not Epub Abstract:
Translational regulation plays an important role in gene expression and function. Although the transcriptional dynamics of... Organism or Cell Type:
mouse embryo Citation Extract: Zhang C, Wang M, Li Y, Zhang Y. Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition. Sci Adv. 2022;8(5):eabj3967 doi:10.1126/sciadv.abj3967. |
Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development
Citation:
Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312 Epub:
Not Epub Abstract:
The Zic family of zinc finger transcription factors plays a critical role in multiple developmental processes. Using loss-of-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Sun J, Yoon J, Lee M, Lee H-K, Hwang Y-S, Daar IO. Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development. Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312. |
Prdm16 and Notch functionally and physically interact during artery development
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275 Epub:
Not Epub Abstract:
Proper vascular function requires correct arteriovenous (AV) endothelial cell (EC) differentiation. While Notch and its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Beerens M, Van Wauwe J, Craps S, Daems M, Ashmita KC, Finck C, Wright S, Leigh ND, MacRae CA, Luttun A. Prdm16 and Notch functionally and physically interact during artery development. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275. |
RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration
Citation:
iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411 Epub:
Not Epub Abstract:
Cancer cells experience mechanical confining forces during metastasis and consequently, can alter their migratory mechanisms.... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture:A375, MB-231 Citation Extract: Moriarty RA, Mili S, Stroka KM. RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration. iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411 . |