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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function

Authors:
Trengove M, Wyett R, Liongue C, Ward AC
Citation:
Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241
Epub:
Not Epub
Abstract:
The suppressor of cytokine signaling (SOCS) proteins play important roles in cytokine and growth factor signaling, where they...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Trengove M, Wyett R, Liongue C, Ward AC. Functional Analysis of Zebrafish socs4a: Impacts on the Notochord and Sensory Function. Brain Sci. 2022;12(2):241. doi:10.3390/brainsci12020241.

PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties

Authors:
Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a paediatric muscle-wasting disorder caused by genetic loss of the gene encoding the...
Delivery Method:
i.v. injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Chwalenia K, Oieni J, Zemła J, Lekka M, Ahlskog N, Coenen-Stass AML, McClorey G, Wood MJA, Lomonosova Y, Roberts TC. PPMO-mediated exon skipping induces uniform sarcolemmal dystrophin rescue with dose-dependent restoration of circulating microRNA biomarkers and muscle biophysical properties. bioRxiv. 2022;[preprint] doi:10.1101/2022.01.25.477672.

Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells

Authors:
Uzureau S, Coquerelle C, Vermeiren C, Uzureau P, Van Acker A, Pilotte L, Monteyne D, Acolty V, Vanhollebeke B, Van den Eynde B, Pérez-Morga D, Moser M, Pays E
Citation:
Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8
Epub:
Not Epub
Abstract:
Apolipoproteins L (ApoLs) are Bcl-2-like proteins expressed under inflammatory conditions in myeloid and endothelial cells. We...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: CD8α+ MutuDCs (dendritic cells)
Citation Extract:
Uzureau S, Coquerelle C, Vermeiren C, Uzureau P, Van Acker A, Pilotte L, Monteyne D, Acolty V, Vanhollebeke B, Van den Eynde B, Pérez-Morga D, Moser M, Pays E. Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells. Eur J Immunol. 2016 Aug;46(8):1854-66. doi: 10.1002/eji.201546252. Epub 2016 Jun 8.

The H3.3 chaperone Hira complex orchestrates oocyte developmental competence

Authors:
Smith R, Susor A, Ming H, Tait J, Conti M, Jiang Z, Lin CJ
Citation:
Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print
Epub:
Not Epub
Abstract:
Successful reproduction requires an oocyte competent to sustaining early embryo development. By the end of oogenesis, the...
Delivery Method:
microinjection
Organism or Cell Type:
mouse embryo
Citation Extract:
Smith R, Susor A, Ming H, Tait J, Conti M, Jiang Z, Lin CJ. The H3.3 chaperone Hira complex orchestrates oocyte developmental competence. Development. 2022 Feb 3:dev.200044. doi: 10.1242/dev.200044. Online ahead of print.

Pivotal role of PIM2 kinase in plasmablast generation and plasma cell survival, opening new treatment options in myeloma

Authors:
Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T
Citation:
Blood. 2022 Feb 2:blood.2021014011. doi:10.1182/blood.2021014011. Online ahead of print
Epub:
Yes
Abstract:
The differentiation of B cells into plasmablasts (PBs) and then plasma cells (PCs) is associated with extensive cell...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: human B cell
Citation Extract:
Haas M, Caron G, Chatonnet F, Manenti S, Alaterre E, Devin J, Delaloy C, Bertolin G, Viel R, Pignarre A, Llamas Gutierrez F, Marchalot A, Decaux O, Tarte K, Delpy L, Moreaux J, Fest T. Pivotal role of PIM2 kinase in plasmablast generation and plasma cell survival, opening new treatment options in myeloma. Blood. 2022 Feb 2:blood.2021014011. doi:10.1182/blood.2021014011. Online ahead of print.

Chordacentrum mineralization is delayed in zebrafish betaglycan-null mutants

Authors:
Molina-Villa T, Ramírez-Vidal L, Mendoza V, Escalante-Alcalde D, López-Casillas F
Citation:
Dev Dyn. 2022 Jan;251(1):213-225. doi: 10.1002/dvdy.393. Epub 2021 Jul 17
Epub:
Not Epub
Abstract:
Background: The Transforming Growth Factor β (TGFβ) family is a group of related proteins that signal through a type I and type...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Molina-Villa T, Ramírez-Vidal L, Mendoza V, Escalante-Alcalde D, López-Casillas F. Chordacentrum mineralization is delayed in zebrafish betaglycan-null mutants. Dev Dyn. 2022 Jan;251(1):213-225. doi: 10.1002/dvdy.393. Epub 2021 Jul 17.

Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition

Authors:
Zhang C, Wang M, Li Y, Zhang Y
Citation:
Sci Adv. 2022;8(5):eabj3967 doi:10.1126/sciadv.abj3967
Epub:
Not Epub
Abstract:
Translational regulation plays an important role in gene expression and function. Although the transcriptional dynamics of...
Organism or Cell Type:
mouse embryo
Citation Extract:
Zhang C, Wang M, Li Y, Zhang Y. Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition. Sci Adv. 2022;8(5):eabj3967 doi:10.1126/sciadv.abj3967.

Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development

Authors:
Sun J, Yoon J, Lee M, Lee H-K, Hwang Y-S, Daar IO
Citation:
Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312
Epub:
Not Epub
Abstract:
The Zic family of zinc finger transcription factors plays a critical role in multiple developmental processes. Using loss-of-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Sun J, Yoon J, Lee M, Lee H-K, Hwang Y-S, Daar IO. Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development. Cell Rep. 2022;38(5):110312 doi:10.1016/j.celrep.2022.110312.

Prdm16 and Notch functionally and physically interact during artery development

Authors:
Beerens M, Van Wauwe J, Craps S, Daems M, Ashmita KC, Finck C, Wright S, Leigh ND, MacRae CA, Luttun A
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275
Epub:
Not Epub
Abstract:
Proper vascular function requires correct arteriovenous (AV) endothelial cell (EC) differentiation. While Notch and its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beerens M, Van Wauwe J, Craps S, Daems M, Ashmita KC, Finck C, Wright S, Leigh ND, MacRae CA, Luttun A. Prdm16 and Notch functionally and physically interact during artery development. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.05.471275.

RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration

Authors:
Moriarty RA, Mili S, Stroka KM
Citation:
iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411
Epub:
Not Epub
Abstract:
Cancer cells experience mechanical confining forces during metastasis and consequently, can alter their migratory mechanisms....
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture:A375, MB-231
Citation Extract:
Moriarty RA, Mili S, Stroka KM. RNA Localization in Confined Cells Depends on Cellular Mechanical Activity and Contributes to Confined Migration. iScience. 2022;[Epub ahead of print] doi:10.2139/ssrn.3878411 .

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