You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle

Authors:
Levin JB, Borodinsky LN
Citation:
Cell Calcium. 2022;[Epub] doi:10.1016/j.ceca.2022.102540
Epub:
Yes
Abstract:
The transition of stem cells from quiescence to proliferation enables tissues to self-repair. The signaling mechanisms driving...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Levin JB, Borodinsky LN. Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle. Cell Calcium. 2022;[Epub] doi:10.1016/j.ceca.2022.102540.

Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis

Authors:
Owen N, Toms M, Young RM, Eintracht J, Sarkar H, Brooks BP, Moosajee M; Genomics England Research Consortium
Citation:
Genet Med. 2022 Jan 13:S1098-3600(21)05473-3. doi: 10.1016/j.gim.2021.12.014. Online ahead of print
Epub:
Yes
Abstract:
Purpose: Ocular coloboma arises from genetic or environmental perturbations that inhibit optic fissure (OF) fusion during early...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Owen N, Toms M, Young RM, Eintracht J, Sarkar H, Brooks BP, Moosajee M; Genomics England Research Consortium. Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis. Genet Med. 2022 Jan 13:S1098-3600(21)05473-3. doi: 10.1016/j.gim.2021.12.014. Online ahead of print.

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RW(d)

Authors:
Lee H, Sun R, Niehrs C
Citation:
J Biol Chem. 2022 Jan 12:101586. doi: 10.1016/j.jbc.2022.101586. Online ahead of print
Epub:
Yes
Abstract:
Signaling by bone morphogenetic proteins (BMPs) plays pivotal roles in embryogenesis, adult tissue homeostasis, and disease....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Lee H, Sun R, Niehrs C. Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RW(d). J Biol Chem. 2022 Jan 12:101586. doi: 10.1016/j.jbc.2022.101586. Online ahead of print.

Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis

Authors:
Tejeda-Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis EM
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.01.11.475934
Epub:
Not Epub
Abstract:
During canonical Wnt signaling, the Lrp6 and Frizzled co-receptors bind to the Wnt growth factor and the complex is endocytosed...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tejeda-Muñoz N, Morselli M, Moriyama Y, Sheladiya P, Pellegrini M, De Robertis EM. Canonical Wnt Signaling Induces Focal Adhesion and Integrin Beta-1 Endocytosis. bioRxiv. 2022;[preprint] doi:10.1101/2022.01.11.475934.

Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning

Authors:
Rosa A, Giese W, Meier K, Alt S, Klaus-Bergmann A, Edgar LT, Bartels E, Collins R, Szymborska A, Coxam B, Bernabeu MO, Gerhardt H
Citation:
Development. 2021 Dec 21:dev.200195. doi: 10.1242/dev.200195. Online ahead of print
Epub:
Yes
Abstract:
Endothelial cell migration and proliferation are essential for the establishment of a hierarchical organization of blood...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosa A, Giese W, Meier K, Alt S, Klaus-Bergmann A, Edgar LT, Bartels E, Collins R, Szymborska A, Coxam B, Bernabeu MO, Gerhardt H. Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning. Development. 2021 Dec 21:dev.200195. doi: 10.1242/dev.200195. Online ahead of print.

Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression

Authors:
Tai Z, Li L, Zhao G, Liu JX
Citation:
Angiogenesis. 2022 Jan 16. doi: 10.1007/s10456-021-09827-0. Online ahead of print
Epub:
Yes
Abstract:
Molecular transport and cell circulation between tissues and organs through blood and lymphatic vessels are essential for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tai Z, Li L, Zhao G, Liu JX. Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression. Angiogenesis. 2022 Jan 16. doi: 10.1007/s10456-021-09827-0. Online ahead of print.

KEPI Plays a Negative Role in the Repression that Accompanies Translational Inhibition Guided by the uORF Element of Human chop Transcript during Stress Response

Authors:
Lee HC, Hsieh CC, Tsai HJ
Citation:
Gene. 2022 Jan 11:146160. doi: 10.1016/j.gene.2021.146160. Online ahead of print
Epub:
Yes
Abstract:
Translation of the downstream coding sequence of some mRNAs may be repressed by the upstream open reading frame (uORF) at their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee HC, Hsieh CC, Tsai HJ. KEPI Plays a Negative Role in the Repression that Accompanies Translational Inhibition Guided by the uORF Element of Human chop Transcript during Stress Response. Gene. 2022 Jan 11:146160. doi: 10.1016/j.gene.2021.146160. Online ahead of print.

Tfap2b specifies an embryonic melanocyte stem cell that retains adult multifate potential

Authors:
Brombin A, Simpson DJ, Travnickova J, Brunsdon H, Zeng Z, Lu Y, Young AIJ, Chandra T, Patton EE
Citation:
Cell Rep. 2022 Jan 11;38(2):110234. doi: 10.1016/j.celrep.2021.110234
Epub:
Not Epub
Abstract:
Melanocytes, the pigment-producing cells, are replenished from multiple stem cell niches in adult tissue. Although pigmentation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brombin A, Simpson DJ, Travnickova J, Brunsdon H, Zeng Z, Lu Y, Young AIJ, Chandra T, Patton EE. Tfap2b specifies an embryonic melanocyte stem cell that retains adult multifate potential. Cell Rep. 2022 Jan 11;38(2):110234. doi: 10.1016/j.celrep.2021.110234.

Numb is required for optimal contraction of skeletal muscle

Authors:
De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu XH, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP
Citation:
J Cachexia Sarcopenia Muscle. 2022 Jan 9. doi: 10.1002/jcsm.12907. Online ahead of print
Epub:
Yes
Abstract:
Background: The role of Numb, a protein that is important for cell fate and development and that, in human muscle, is expressed...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: mouse primary myoblasts, myotubes
Citation Extract:
De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu XH, Guo L, Zhang B, Ko F, Raczkowski AM, Bauman WA, Goulbourne CN, Zhao W, Brotto M, Cardozo CP. Numb is required for optimal contraction of skeletal muscle. J Cachexia Sarcopenia Muscle. 2022 Jan 9. doi: 10.1002/jcsm.12907. Online ahead of print.

An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes

Authors:
Budzak J, Jones R, Tschudi C, Kolev NG, Rudenko G
Citation:
Nat Commun. 2022 Jan 10;13(1):101. doi: 10.1038/s41467-021-27625-6
Epub:
Not Epub
Abstract:
A Variant Surface Glycoprotein (VSG) coat protects bloodstream form Trypanosoma brucei. Prodigious amounts of VSG mRNA (~7-10%...
Delivery Method:
electroporation
Organism or Cell Type:
Trypanosoma brucei
Citation Extract:
Budzak J, Jones R, Tschudi C, Kolev NG, Rudenko G. An assembly of nuclear bodies associates with the active VSG expression site in African trypanosomes. Nat Commun. 2022 Jan 10;13(1):101. doi: 10.1038/s41467-021-27625-6.

Pages