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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Different requirements for GATA factors in cardiogenesis are mediated by non-canonical Wnt signaling

Authors:
Afouda BA, Hoppler S
Citation:
Dev Dyn. 2011 Mar;240(3):649-62. doi:10.1002/dvdy.22570. Epub 2011 Feb 8
Epub:
Not Epub
Abstract:
GATA factors and Wnt signals are key regulators of vertebrate cardiogenesis, but specific roles for individual GATA factors and...
Link:
https://anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.22570
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Afouda BA, Hoppler S. Different requirements for GATA factors in cardiogenesis are mediated by non-canonical Wnt signaling. Dev Dyn. 2011 Mar;240(3):649-62. doi:10.1002/dvdy.22570. Epub 2011 Feb 8.

FoxN3 knock-down alters spatio-temporal expression patterns of genes involved in cranial cartilage and muscle development in the African clawed-frog Xenopus laevis

Authors:
Schmidt J, Schuff M, Naumann B, Olsson L
Citation:
Vertebr Zool. 2020;70(3)455-72. doi:10.26049/VZ70-3-2020-14
Epub:
Not Epub
Abstract:
What is the gene regulatory network underlying the morphogenesis of the vertebrate head skeleton? A good candidate to approach...
Link:
https://www.senckenberg.de/wp-content/uploads/2020/09/14_vertebrate_zoology_70_3_2020_Schmidt.pdf
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Schmidt J, Schuff M, Naumann B, Olsson L. FoxN3 knock-down alters spatio-temporal expression patterns of genes involved in cranial cartilage and muscle development in the African clawed-frog Xenopus laevis. Vertebr Zool. 2020;70(3)455-72. doi:10.26049/VZ70-3-2020-14.

Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2

Authors:
Capon SJ, Uribe V, Dominado N, Ehrlich O, Smith KA
Citation:
Development. 2022 May 1;149(9):dev190421. doi: 10.1242/dev.190421. Epub 2022 May 9
Epub:
Not Epub
Abstract:
The endocardium plays important roles in the development and function of the vertebrate heart; however, few molecular markers...
Link:
https://journals.biologists.com/dev/article/149/9/dev190421/275317/Endocardial-identity-is-established-during-early
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Capon SJ, Uribe V, Dominado N, Ehrlich O, Smith KA. Endocardial identity is established during early somitogenesis by Bmp signalling acting upstream of npas4l and etv2. Development. 2022 May 1;149(9):dev190421. doi: 10.1242/dev.190421. Epub 2022 May 9.

Xenopus Dusp6 modulates FGF signaling precisely to pattern pre-placodal ectoderm

Authors:
Tsukano K, Yamamoto T, Watanabe T, Michiue T
Citation:
Dev Biol. 2022 May 19:S0012-1606(22)00097-5. doi: 10.1016/j.ydbio.2022.05.009. Online ahead of print
Epub:
Yes
Abstract:
Pre-placodal ectoderm (PPE), a horseshoe-shaped narrow region formed during early vertebrate development, gives rise to...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160622000975
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Tsukano K, Yamamoto T, Watanabe T, Michiue T. Xenopus Dusp6 modulates FGF signaling precisely to pattern pre-placodal ectoderm. Dev Biol. 2022 May 19:S0012-1606(22)00097-5. doi: 10.1016/j.ydbio.2022.05.009. Online ahead of print.

Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development

Authors:
Wang YY, Nie L, Xu XX, Shao T, Fan DD, Lin AF, Xiang LX, Shao JZ
Citation:
Immunohorizons. 2022 May 19;6(5):283-298. doi: 10.4049/immunohorizons.2200028
Epub:
Not Epub
Abstract:
Retinoic acid-inducible gene I (RIG-I) is an important cytosolic pattern recognition receptor crucial for sensing RNA virus...
Link:
https://www.immunohorizons.org/content/6/5/283
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang YY, Nie L, Xu XX, Shao T, Fan DD, Lin AF, Xiang LX, Shao JZ. Essential Role of RIG-I in Hematopoietic Precursor Emergence in Primitive Hematopoiesis during Zebrafish Development. Immunohorizons. 2022 May 19;6(5):283-298. doi: 10.4049/immunohorizons.2200028.

Huang Y, Winklbauer R

Authors:
Cell cortex regulation by the planar cell polarity protein Prickle1
Citation:
J Cell Biol. 2022 Jul 4;221(7):e202008116. doi: 10.1083/jcb.202008116. Epub 2022 May 5
Epub:
Not Epub
Abstract:
The planar cell polarity pathway regulates cell polarity, adhesion, and rearrangement. Its cytoplasmic core components Prickle...
Link:
https://rupress.org/jcb/article-abstract/221/7/e202008116/213195/Cell-cortex-regulation-by-the-planar-cell-polarity
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Cell cortex regulation by the planar cell polarity protein Prickle1. Huang Y, Winklbauer R. J Cell Biol. 2022 Jul 4;221(7):e202008116. doi: 10.1083/jcb.202008116. Epub 2022 May 5.

Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases

Authors:
Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O
Citation:
Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11
Epub:
Not Epub
Abstract:
Regnase-1 is an ribonuclease that plays essential roles in restricting inflammation through degrading messenger RNAs (mRNAs)...
Link:
https://www.science.org/doi/10.1126/scitranslmed.abo2137
Delivery Method:
intratracheal, intracranial injection, Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
mice, cell culture: HeLa, Raw264.7, mouse peritoneal macrophages, murine bone marrow-derived macrophages (BMDMs), murine CD4+ T cells
Citation Extract:
Tse KM, Vandenbon A, Cui X, Mino T, Uehata T, Yasuda K, Sato A, Tsujimura T, Hia F, Yoshinaga M, Kinoshita M, Okuno T, Takeuchi O. Enhancement of Regnase-1 expression with stem loop-targeting antisense oligonucleotides alleviates inflammatory diseases. Sci Transl Med. 2022 May 11;14(644):eabo2137. doi: 10.1126/scitranslmed.abo2137. Epub 2022 May 11.

Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation

Authors:
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y
Citation:
J Extracell Vesicles. 2022 May;11(5):e12221. doi: 10.1002/jev2.12221
Epub:
Not Epub
Abstract:
Tumour-associated angiogenesis plays a critical role in metastasis, the main cause of malignancy-related death. Extracellular...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1002/jev2.12221
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
You B, Pan S, Gu M, Zhang K, Xia T, Zhang S, Chen W, Xie H, Fan Y, Yao H, Cheng T, Zhang P, Liu D, You Y. Extracellular vesicles rich in HAX1 promote angiogenesis by modulating ITGB6 translation. J Extracell Vesicles. 2022 May;11(5):e12221. doi: 10.1002/jev2.12221.

RanBP1 plays an essential role in directed migration of neural crest cells during development

Authors:
Barriga EH, Alasaadi DN, Mencarelli C, Mayor R, Pichaud F
Citation:
bioRxiv. 2022:490747. doi:10.1101/2022.05.05.490747
Epub:
Not Epub
Abstract:
Collective cell migration is essential for embryonic development, tissue regeneration and repair, and has been implicated in...
Link:
https://www.biorxiv.org/content/10.1101/2022.05.05.490747v2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Barriga EH, Alasaadi DN, Mencarelli C, Mayor R, Pichaud F. RanBP1 plays an essential role in directed migration of neural crest cells during development. bioRxiv. 2022:490747. doi:10.1101/2022.05.05.490747 .

Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis

Authors:
Heilig AK, Nakamura R, Shimada A, Hashimoto Y, Nakamura Y, Wittbrodt J, Takeda H, Kawanishi T
Citation:
eLife. 2022;11:e71845. doi:10.7554/eLife.71845
Epub:
Not Epub
Abstract:
The dorsal axial muscles, or epaxial muscles, are a fundamental structure covering the spinal cord and vertebrae, as well as...
Link:
https://elifesciences.org/articles/71845
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Heilig AK, Nakamura R, Shimada A, Hashimoto Y, Nakamura Y, Wittbrodt J, Takeda H, Kawanishi T. Wnt11 acts on dermomyotome cells to guide epaxial myotome morphogenesis. eLife. 2022;11:e71845. doi:10.7554/eLife.71845.

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