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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly
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Citation:
Front Cell Dev Biol. 2022;10:844619. doi:10.3389/fcell.2022.844619 Epub:
Not Epub Abstract:
Retinoic acid (RA) is a central signaling molecule regulating multiple developmental decisions during embryogenesis. Excess RA... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gur M, Bendelac-Kapon L, Shabtai Y, Pillemer G, Fainsod A. Reduced Retinoic Acid Signaling During Gastrulation Induces Developmental Microcephaly. Front Cell Dev Biol. 2022;10:844619. doi:10.3389/fcell.2022.844619. |
Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder
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Citation:
Front Cell Infect Microbiol. 2022;12:790851. doi:10.3389/fcimb.2022.790851 Epub:
Not Epub Abstract:
Animal models are essential to understanding COVID-19 pathophysiology and for preclinical assessment of drugs and other... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Laghi V, Rezelj V, Boucontet L, Frétaud M, Da Costa B, Boudinot P, Salinas I, Lutfalla G, Vignuzzi M, Levraud J-P. Exploring Zebrafish Larvae as a COVID-19 Model: Probable Abortive SARS-CoV-2 Replication in the Swim Bladder. Front Cell Infect Microbiol. 2022;12:790851. doi:10.3389/fcimb.2022.790851. |
The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways
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Citation:
Front Cell Dev Biol. 2022 Feb 22;10:777121. doi: 10.3389/fcell.2022.777121. eCollection 2022 Epub:
Not Epub Abstract:
Ribosomal biogenesis is a fundamental process necessary for cell growth and division. Ribosomal protein L5 (Rpl5) is part of... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Schreiner C, Kernl B, Dietmann P, Riegger RJ, Kühl M, Kühl SJ. The Ribosomal Protein L5 Functions During Xenopus Anterior Development Through Apoptotic Pathways. Front Cell Dev Biol. 2022 Feb 22;10:777121. doi: 10.3389/fcell.2022.777121. eCollection 2022. |
d-Serine controls epidermal vesicle release via NMDA receptor, allowing tissue migration during the metamorphosis of the chordate Ciona
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Citation:
Sci Adv. 2022;8(10):eabn3264. doi:10.1126/sciadv.abn3264 Epub:
Not Epub Abstract:
d-Serine, a free amino acid synthesized by serine racemase, is a coagonist of N-methyl-d-aspartate–type glutamate receptor (... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Krasovec G, Hozumi A, Yoshida T, Obita T, Hamada M, Shiraishi A, Satake H, Horie T, Mori H, Sasakura Y. d-Serine controls epidermal vesicle release via NMDA receptor, allowing tissue migration during the metamorphosis of the chordate Ciona. Sci Adv. 2022;8(10):eabn3264. doi:10.1126/sciadv.abn3264. |
Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis
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Citation:
Development. 2022;149(5):dev200231. doi:10.1242/dev.200231 Epub:
Not Epub Abstract:
Mammalian oocyte maturation is a unique asymmetric division, which is mainly because of actin-based spindle migration to the... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Shan M-M, Zou Y-J, Pan Z-N, Zhang H-L, Xu Y, Ju J-Q, Sun S-C. Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis. Development. 2022;149(5):dev200231. doi:10.1242/dev.200231. |
Morpholino-driven blockade of Dkk-1 in osteosarcoma inhibits bone damage and tumour expansion by multiple mechanisms
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Citation:
Br J Cancer. 2022 Jul;127(1):43-55. doi: 10.1038/s41416-022-01764-z. Epub 2022 Mar 11 Epub:
Not Epub Abstract:
Background: Osteosarcoma (OS) is the most common primary bone malignancy. Chemotherapy plays an essential role in OS treatment... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: (RFP)-labeled MOSJ-Dkk1 murine osteochondral sarcoma line, xenograft in Foxn1-/Foxn1- mice Citation Extract: Pan S, Cesarek M, Godoy C, Co CM, Schindler C, Padilla K, Haskell A, Barreda H, Story C, Poole R, Dabney A, Gregory CA. Morpholino-driven blockade of Dkk-1 in osteosarcoma inhibits bone damage and tumour expansion by multiple mechanisms. Br J Cancer. 2022 Jul;127(1):43-55. doi: 10.1038/s41416-022-01764-z. Epub 2022 Mar 11. |
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis
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Citation:
Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print Epub:
Not Epub Abstract:
Background: Retinoblastoma-binding protein 4 (Rbbp4) is a component of transcription regulatory complexes that control cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schultz-Rogers LE, Thayer ML, Kambakam S, Wierson WA, Helmer JA, Wishman MD, Wall KA, Greig JL, Forsman JL, Puchhalapalli K, Nair S, Weiss TJ, Luiken JM, Blackburn PR, Ekker SC, Kool M, McGrail M. Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis. Dev Dyn. 2022 Mar 9. doi: 10.1002/dvdy.467. Online ahead of print. |
SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling
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Citation:
Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0 Epub:
Yes Abstract:
Breast cancer stem cells (BCSCs) are the main drivers of recurrence and metastasis. However, commonly used drugs rarely target... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rong Z, Zhang L, Li Z, Xiao Z, Duan Y, Ren X, Zi Y, Gao J, Mu Y, Guan Y, Cao Z, Wang X, Pei Q, Zeng Y, Fan Q, Zeng Z, Ou D, He J, Nie Y, Tan R, Weng L, Li Y, Xiang R, Deng Y, Sun L. SIK2 maintains breast cancer stemness by phosphorylating LRP6 and activating Wnt/β-catenin signaling. Oncogene. 2022;[Epub] doi:10.1038/s41388-022-02259-0. |
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth
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Citation:
Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. Epub:
Not Epub Abstract:
During embryogenesis, the initial vascular network forms by the process of vasculogenesis, or the specification of vascular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Metikala S, Warkala M, Chetty SC, Chestnut B, Florat DR, Plender E, Nester O, Koenig AL, Astrof S, Sumanas S. Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth. Dev Cell. 2022 Mar 28;57(6):767-782.e6. doi: 10.1016/j.devcel.2022.02.015. Epub 2022 Mar 10. . |
ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis
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Citation:
Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3 Epub:
Not Epub Abstract:
Primary cilia are antenna-like subcellular structures to act as signaling platforms to regulate many cellular processes and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T. ALKBH3-dependent m1A demethylation of Aurora A mRNA inhibits ciliogenesis. Cell Discov. 2022;8(1):25 doi:10.1038/s41421-022-00385-3. |