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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations

Authors:
Hong T, Xiao X, Ren J, Cui B, Zong Y, Zou J, Kou Z, Jiang N, Meng G, Zeng G, Shan Y, Wu H, Chen Z, Liang J, Xiao X, Tang J, Wei Y, Ye M, Sun L, Li G, Hu P, Hui R, Zhang H, Wang Y
Citation:
Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117
Epub:
Not Epub
Abstract:
Cavernous malformations affecting the CNS occur in ∼0.16-0.4% of the general population. The majority (85%) of cavernous...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hong T, Xiao X, Ren J, Cui B, Zong Y, Zou J, Kou Z, Jiang N, Meng G, Zeng G, Shan Y, Wu H, Chen Z, Liang J, Xiao X, Tang J, Wei Y, Ye M, Sun L, Li G, Hu P, Hui R, Zhang H, Wang Y. Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations. Brain. 2021 Oct 22;144(9):2648-2658. doi: 10.1093/brain/awab117.

miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway

Authors:
Huang Y, Wang W-F, Huang C-X, Li X-H, Liu H, Wang H-L
Citation:
Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133
Epub:
Not Epub
Abstract:
Background: Zebrafish miR-731 is orthologous of human miR-425, which has been demonstrated to have cardio-protective roles by a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang Y, Wang W-F, Huang C-X, Li X-H, Liu H, Wang H-L. miR-731 modulates the zebrafish heart morphogenesis via targeting Calcineurin/Nfatc3a pathway. Biochim Biophys Acta Gen Subj. 2022;1866(6):130133. doi:10.1016/j.bbagen.2022.130133.

LAMP2A regulates the loading of proteins into exosomes

Authors:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P
Citation:
Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140
Epub:
Not Epub
Abstract:
Exosomes are extracellular vesicles of endosomal origin that are released by practically all cell types across metazoans....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ferreira JV, da Rosa Soares A, Ramalho J, Carvalho CM, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P. LAMP2A regulates the loading of proteins into exosomes. Sci Adv. 2022;8(12):[Epub] doi:10.1126/sciadv.abm1140.

Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries

Authors:
Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E, Earley S
Citation:
Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021
Epub:
Not Epub
Abstract:
Nitric oxide (NO) relaxes vascular smooth muscle cells (SMCs) and dilates blood vessels by increasing intracellular levels of...
Delivery Method:
lipofectamine 2000
Organism or Cell Type:
explants: cerebral arteries
Citation Extract:
Ali S, Solano AS, Gonzales AL, Thakore P, Krishnan V, Yamasaki E, Earley S. Nitric Oxide Signals Through IRAG to Inhibit TRPM4 Channels and Dilate Cerebral Arteries. Function (Oxf). 2021 Oct 9;2(6):zqab051. doi: 10.1093/function/zqab051. eCollection 2021.

Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage

Authors:
Zhao S, Feng S, Tian Y, Wen Z
Citation:
Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2119051119. doi: 10.1073/pnas.2119051119. Epub 2022 Mar 25
Epub:
Not Epub
Abstract:
Hematopoietic stem cells (HSCs) are generated from hemogenic endothelial cells (HECs) in the floor of the dorsal aorta (DA) via...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao S, Feng S, Tian Y, Wen Z. Hemogenic and aortic endothelium arise from a common hemogenic angioblast precursor and are specified by the Etv2 dosage. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2119051119. doi: 10.1073/pnas.2119051119. Epub 2022 Mar 25.

Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish

Authors:
Thrikawala S, Niu M, Keller NP, Rosowski EE
Citation:
PLoS Pathog. 2022;18(3):e1010040. doi:10.1371/journal.ppat.1010040
Epub:
Not Epub
Abstract:
Invasive aspergillosis is a common opportunistic infection, causing >50% mortality in infected immunocompromised patients....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thrikawala S, Niu M, Keller NP, Rosowski EE. Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish. PLoS Pathog. 2022;18(3):e1010040. doi:10.1371/journal.ppat.1010040.

Molecularly resolved, label-free nucleic acid sensing at solid-liquid interface using non-ionic DNA analogues

Authors:
Mana T, Kundu J, Lahiri H, Bera S, Kolay J, Sinha S, Mukhopadhyay R
Citation:
RSC Adv. 2022;12:9263-74. doi:10.1039/D2RA00386D
Epub:
Not Epub
Abstract:
Nucleic acid-based biosensors, where the capture probe is a nucleic acid, e.g., DNA or its synthetic analogue xeno nucleic acid...
Citation Extract:
Mana T, Kundu J, Lahiri H, Bera S, Kolay J, Sinha S, Mukhopadhyay R. Molecularly resolved, label-free nucleic acid sensing at solid-liquid interface using non-ionic DNA analogues. RSC Adv. 2022;12:9263-74. doi:10.1039/D2RA00386D.

Role of the Basolateral Na+/H+ Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes)

Authors:
Liu S-T, Horng J-L, Lin L-Y
Citation:
Front Physiol. 2022;13:870967. doi:10.3389/fphys.2022.870967
Epub:
Not Epub
Abstract:
Ionocytes in the skin and gills of seawater (SW) fishes are responsible for acid-base regulation and salt secretion. Na+/H+...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (Medaka)
Citation Extract:
Liu S-T, Horng J-L, Lin L-Y. Role of the Basolateral Na+/H+ Exchanger-2 (NHE2) in Ionocytes of Seawater- Acclimated Medaka (Oryzias latipes). Front Physiol. 2022;13:870967. doi:10.3389/fphys.2022.870967.

Disc and actin-associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia

Authors:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR
Citation:
PLoS Pathog. 2022 Mar 25;18(3):e1010433. doi: 10.1371/journal.ppat.1010433. Online ahead of print
Epub:
Not Epub
Abstract:
The deep-branching eukaryote Giardia lamblia is an extracellular parasite that attaches to the host intestine via a microtubule...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. Disc and actin-associated Protein 1 influences attachment in the intestinal parasite Giardia lamblia. PLoS Pathog. 2022 Mar 25;18(3):e1010433. doi: 10.1371/journal.ppat.1010433. Online ahead of print.

From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergence

Authors:
Kotov A, Alkobtawi M, Seal S, Kappes V, Ruiz SM, Arbes H, Harland R, Peshkin L, Monsoro-Burq AH
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.03.23.485460
Epub:
Not Epub
Abstract:
Neural crest cells exemplify cellular diversification from a multipotent progenitor population. However, the full sequence of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kotov A, Alkobtawi M, Seal S, Kappes V, Ruiz SM, Arbes H, Harland R, Peshkin L, Monsoro-Burq AH. From neural border to migratory stage: A comprehensive single cell roadmap of the timing and regulatory logic driving cranial and vagal neural crest emergence. bioRxiv. 2022;[preprint] doi:10.1101/2022.03.23.485460.

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