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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
MNK2 deficiency potentiates β-cell regeneration via translational regulation
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Citation:
Nat Chem Biol. 2022 Jun 13. doi: 10.1038/s41589-022-01047-x. Online ahead of print Epub:
Not Epub Abstract:
Regenerating pancreatic β-cells is a potential curative approach for diabetes. We previously identified the small molecule... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Karampelias C, Watt K, Mattsson CL, Ruiz ÁF, Rezanejad H, Mi J, Liu X, Chu L, Locasale JW, Korbutt GS, Rovira M, Larsson O, Andersson O. MNK2 deficiency potentiates β-cell regeneration via translational regulation. Nat Chem Biol. 2022 Jun 13. doi: 10.1038/s41589-022-01047-x. Online ahead of print. |
Downregulation of Yap1 During Limb Regeneration Results in Defective Bone Formation in Axolotl
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.12.495807 Epub:
Not Epub Abstract:
The Hippo pathway plays an imperative role in cellular processes such as differentiation, regeneration, cell migration, organ... Delivery Method:
injection then electroporation Organism or Cell Type:
Ambystoma mexicanum (axlotl) Citation Extract: Bay S, Öztürk G, Emekli N, Demircan T. Downregulation of Yap1 During Limb Regeneration Results in Defective Bone Formation in Axolotl. bioRxiv. 2022;[preprint] doi:10.1101/2022.06.12.495807. |
Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity
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Citation:
Bioconjug Chem. 2022 Jun 23. doi: 10.1021/acs.bioconjchem.2c00199. Online ahead of print Epub:
Yes Abstract:
The secondary structures of cell-penetrating peptides (CPPs) influence their properties including their cell-membrane... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa 705 Citation Extract: Takada H, Tsuchiya K, Demizu Y. Helix-Stabilized Cell-Penetrating Peptides for Delivery of Antisense Morpholino Oligomers: Relationships among Helicity, Cellular Uptake, and Antisense Activity. Bioconjug Chem. 2022 Jun 23. doi: 10.1021/acs.bioconjchem.2c00199. Online ahead of print. |
Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model
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Citation:
Cell Microbiol. 2022;2022:9429516. doi:10.1155/2022/9429516 Epub:
Not Epub Abstract:
Streptococcus pneumoniae (the pneumococcus) is a major human pathogen causing invasive disease, including community-acquired... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Prajsnar TK, Michno BJ, Pooranachandran N, Fenton AK, Mitchell TJ, Dockrell DH, Renshaw SA. Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model. Cell Microbiol. 2022;2022:9429516. doi:10.1155/2022/9429516. |
Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme
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Citation:
EMBO Rep. 2022 Jun 9:e54464. doi: 10.15252/embr.202154464. Online ahead of print Epub:
Not Epub Abstract:
Immigration of mesenchymal cells into the growing fin and limb buds drives distal outgrowth, with subsequent tensile forces... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mahabaleshwar H, Asharani PV, Loo TY, Koh SY, Pitman MR, Kwok S, Ma J, Hu B, Lin F, Li Lok X, Pitson SM, Saunders TE, Carney TJ. Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme. EMBO Rep. 2022 Jun 9:e54464. doi: 10.15252/embr.202154464. Online ahead of print. |
N6 -methyladenosine-modified circRNA RERE modulates osteoarthritis by regulating β-catenin ubiquitination and degradation
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Citation:
Cell Prolif. 2022 Jun 22:e13297. doi: 10.1111/cpr.13297. Online ahead of print Epub:
Yes Abstract:
Objectives: N6 -methyladenosine (m6A) is one of the most abundant internal RNA modifications. We investigated the role of m6A-... Delivery Method:
Endo-Porter, Vivo-Morpholino Organism or Cell Type:
cell culture: primary human chondrocytes, mice Citation Extract: Liu Y, Yang Y, Lin Y, Wei B, Hu X, Xu L, Zhang W, Lu J. N6 -methyladenosine-modified circRNA RERE modulates osteoarthritis by regulating β-catenin ubiquitination and degradation. Cell Prolif. 2022 Jun 22:e13297. doi: 10.1111/cpr.13297. Online ahead of print. |
Expression and development of TARP γ-4 in embryonic zebrafish
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Citation:
Dev Neurosci. 2022 Jun 21. doi: 10.1159/000525578. Online ahead of print Epub:
Not Epub Abstract:
Fast excitatory synaptic transmission in the CNS is mediated by the neurotransmitter glutamate, binding to and activating AMPA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ahmed KT, Amin MR, Razmara P, Roy B, Cai R, Tang J, Chen XZ, Ali DW. Expression and development of TARP γ-4 in embryonic zebrafish. Dev Neurosci. 2022 Jun 21. doi: 10.1159/000525578. Online ahead of print. |
Diel rhythm of the inflammatory cytokine il1b in the Japanese medaka (Oryzias latipes) regulated by core components of the circadian clock
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Citation:
Fish Shellfish Immunol. 2022 Jun 17:S1050-4648(22)00338-2. doi: 10.1016/j.fsi.2022.06.020. Online ahead of print Epub:
Yes Abstract:
In recent years, studies on circadian control in immunity have been actively conducted in mammals, but little is known about... Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Takeuchi T, Hata T, Miyanishi H, Yuasa T, Setoguchi S, Takeda A, Morimoto N, Hikima JI, Sakai M, Kono T. Diel rhythm of the inflammatory cytokine il1b in the Japanese medaka (Oryzias latipes) regulated by core components of the circadian clock. Fish Shellfish Immunol. 2022 Jun 17:S1050-4648(22)00338-2. doi: 10.1016/j.fsi.2022.06.020. Online ahead of print. |
Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos
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Citation:
Dev Dyn. 2022 Jun 15. doi:10.1002/dvdy.508. Online ahead of print Epub:
Not Epub Abstract:
Background: Cadherin-associated protein p120 catenin regulates cell adhesion and migration in cell cultures and is required for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kupai A, Nakahara H, Voss KM, Hirano MS, Rodriguez A, Lackey DL, Murayama JF, Mathieson CJ, Shan B, Horton EC, Curtis GH, Huang J, Hille MB. Phosphorylation of serine residues S252, S268/S269, and S879 in p120 catenin activates migration of presomitic mesoderm in gastrulating zebrafish embryos. Dev Dyn. 2022 Jun 15. doi:10.1002/dvdy.508. Online ahead of print. |
Evidence for a novel, effective approach to targeting carcinoma catabolism exploiting the first-in-class, anti-cancer mitochondrial drug, CPI-613
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Citation:
PLoS ONE. 2022;17(6):e0269620. doi:10.1371/journal.pone.0269620 Epub:
Not Epub Abstract:
Clinical targeting of the altered metabolism of tumor cells has long been considered an attractive hypothetical approach.... Delivery Method:
cell bathing, Vivo-Morpholino Organism or Cell Type:
cell culture: AsPC-1 Citation Extract: Guardado Rivas MO, Stuart SD, Thach D, Dahan M, Shorr R, Zachar Z, Bingham PM. Evidence for a novel, effective approach to targeting carcinoma catabolism exploiting the first-in-class, anti-cancer mitochondrial drug, CPI-613. PLoS ONE. 2022;17(6):e0269620. doi:10.1371/journal.pone.0269620. |