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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Vasa nucleates asymmetric translation along the mitotic spindle during unequal cell divisions
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Citation:
Nat Commun. 2022 Apr 20;13(1):2145. doi: 10.1038/s41467-022-29855-8 Epub:
Not Epub Abstract:
mRNA translation on the spindle is hypothesized to be an essential strategy for the localized production of cell regulators.... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Fernandez-Nicolas A, Uchida A, Poon J, Yajima M. Vasa nucleates asymmetric translation along the mitotic spindle during unequal cell divisions. Nat Commun. 2022 Apr 20;13(1):2145. doi: 10.1038/s41467-022-29855-8. |
Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis
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Citation:
Sci Adv. 2022 Apr 22;8(16):eabi7109. doi:10.1126/sciadv.abi7109. Epub 2022 Apr 20 Epub:
Not Epub Abstract:
Neurons are highly specialized cells present in nearly all animals, but their evolutionary origin and relationship to other... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Tournière O, Gahan JM, Busengdal H, Bartsch N, Rentzsch F. Insm1-expressing neurons and secretory cells develop from a common pool of progenitors in the sea anemone Nematostella vectensis. Sci Adv. 2022 Apr 22;8(16):eabi7109. doi:10.1126/sciadv.abi7109. Epub 2022 Apr 20. |
A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis
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Citation:
Mol Cell Biol. 2015 Feb;35(4):758-68. doi: 10.1128/MCB.01040-14. Epub 2014 Dec 15 Epub:
Not Epub Abstract:
The output of alternative splicing depends on the cooperative or antagonistic activities of several RNA-binding proteins (RBPs... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Méreau A, Anquetil V, Lerivray H, Viet J, Schirmer C, Audic Y, Legagneux V, Hardy S, Paillard L. A posttranscriptional mechanism that controls Ptbp1 abundance in the Xenopus epidermis. Mol Cell Biol. 2015 Feb;35(4):758-68. doi: 10.1128/MCB.01040-14. Epub 2014 Dec 15. |
Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development
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Citation:
Development. 2022 Apr 1;149(7):dev198341. doi: 10.1242/dev.198341. Epub 2022 Apr 14 Epub:
Not Epub Abstract:
Embryonic aneuploidy is highly complex, often leading to developmental arrest, implantation failure or spontaneous miscarriage... Delivery Method:
Endo-Porter (cultures), microinjection (zygotes) Organism or Cell Type:
cell culture: Madin-Darby Bovine Kidney (MDBK), bovine (Bos taurus) zygotes 20hpf Citation Extract: Brooks KE, Daughtry BL, Davis B, Yan MY, Fei SS, Shepherd S, Carbone L, Chavez SL. Molecular contribution to embryonic aneuploidy and karyotypic complexity in initial cleavage divisions of mammalian development. Development. 2022 Apr 1;149(7):dev198341. doi: 10.1242/dev.198341. Epub 2022 Apr 14. |
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion
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Citation:
iScience. 2022 Mar 9;25(4):104042. doi: 10.1016/j.isci.2022.104042. eCollection 2022 Apr 15 Epub:
Not Epub Abstract:
Extracellular vesicles (EVs) participate in intercellular communication and contribute to the angiogenesis. However, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X. VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion. iScience. 2022 Mar 9;25(4):104042. doi: 10.1016/j.isci.2022.104042. eCollection 2022 Apr 15. |
In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.13.488231 Epub:
Not Epub Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa 654 Citation Extract: Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.13.488231. |
Synthesis of Morpholino Nucleosides Starting From Enantiopure Glycidol
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Citation:
Org Chem Front. 2022;[Epub] doi:10.1039/D2QO00400C Epub:
Yes Abstract:
A protocol for the synthesis of modified morpholino monomers was performed in few steps through the condensation between 6-... Citation Extract: Papis M, Loro C, Penso M, Broggini G, Foschi F. Synthesis of Morpholino Nucleosides Starting From Enantiopure Glycidol. Org Chem Front. 2022;[Epub] doi:10.1039/D2QO00400C. |
Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy
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Citation:
Cells. 2022;11(8):1285. doi:10.3390/cells11081285 Epub:
Not Epub Abstract:
Hypomyelinating leukodystrophies (HLDs) are a rare group of heterogeneously genetic disorders characterized by persistent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan H, Yang S, Hou Y, Ali S, Escobar A, Gao K, Duan R, Kubisiak T, Wang J, Zhang Y, Xiao J, Jiang Y, Zhang T, Wu Y, Burmeister M, Wang Q, Cuajungco MP, Wang J. Functional Study of TMEM163 Gene Variants Associated with Hypomyelination Leukodystrophy. Cells. 2022;11(8):1285. doi:10.3390/cells11081285. |
Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382 Epub:
Not Epub Abstract:
TRIM33 (Tif1-γ) is a transcriptional regulator notably involved in several aspects of hematopoiesis. It is essential for the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Demy DL, Touret A-L, Lancino M, Tauzin M, Capuana L, Pierre C, Herbomel P. Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production. bioRxiv. 2022;[preprint] doi:10.1101/2022.04.06.487382. |
The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans
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Citation:
Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8 Epub:
Not Epub Abstract:
CHARGE syndrome is a complex developmental disorder caused by mutations in the chromodomain helicase DNA-binding protein-7 (... Organism or Cell Type:
Xenopus laevis Citation Extract: Jofré DM, Hoffman DK, Cervino AS, Hahn GM, Grundy M, Yun S, Amrit FRG, Stolz DB, Godoy LF, Salvatore E, Rossi FA, Ghazi A, Cirio MC, Yanowitz JL, Hochbaum D. The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2109508119. doi: 10.1073/pnas.2109508119. Epub 2022 Apr 8. |