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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12351 scientific papers returned from the database with the search filters currently being used below.

Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo

Authors:
Moore RE, Pop S, Alleyne C, Clarke JDW
Citation:
EMBO Rep. 2022 Oct 4:e52493. doi: 10.15252/embr.202152493. Online ahead of print
Epub:
Not Epub
Abstract:
Our understanding of the cell behaviours and cytoskeletal requirements of axon formation is largely derived from in vitro...
Link:
https://www.embopress.org/doi/full/10.15252/embr.202152493
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore RE, Pop S, Alleyne C, Clarke JDW. Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo. EMBO Rep. 2022 Oct 4:e52493. doi: 10.15252/embr.202152493. Online ahead of print.

Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy

Authors:
Becette OB, Marino JP, Brinson RG
Citation:
Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print
Epub:
Yes
Abstract:
Purpose: Antisense oligonucleotide (ASO) therapeutics are an emerging class of biopharmaceuticals to treat and prevent diseases...
Link:
https://pubmed.ncbi.nlm.nih.gov/36195820/
Citation Extract:
Becette OB, Marino JP, Brinson RG. Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy. Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print.

Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development

Authors:
Williams AL, Bohnsack BL
Citation:
J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042
Epub:
Not Epub
Abstract:
Most cases of Stickler syndrome are due to autosomal-dominant COL2A1 gene mutations leading to abnormal type II collagen....
Link:
https://www.mdpi.com/2221-3759/10/4/42
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams AL, Bohnsack BL. Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development. J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042.

An FGF Timer for Zygotic Genome Activation

Authors:
Treen N, Chavarria E, Weaver CJ, Brangwynne CF, Levine M
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450
Epub:
Not Epub
Abstract:
Zygotic genome activation has been extensively studied in a variety of systems including flies, frogs, and mammals. However,...
Link:
https://www.biorxiv.org/content/10.1101/2022.10.01.510450v1
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Treen N, Chavarria E, Weaver CJ, Brangwynne CF, Levine M. An FGF Timer for Zygotic Genome Activation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450.

RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification

Authors:
Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME
Citation:
Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600
Epub:
Not Epub
Abstract:
While neural crest development is known to be transcriptionally controlled via sequential activation of gene regulatory...
Link:
https://elifesciences.org/articles/63600
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600.

Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos

Authors:
Kumar A, Rhee M
Citation:
Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print
Epub:
Yes
Abstract:
Background: Molecular networks associated with dopaminergic (DA) neurogenesis remain undefined within mammalian models. To...
Link:
https://link.springer.com/article/10.1007/s13258-022-01317-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumar A, Rhee M. Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos. Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print.

Cyclin B3 implements timely vertebrate oocyte arrest for fertilization

Authors:
Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU
Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005
Epub:
Not Epub
Abstract:
To ensure successful offspring ploidy, vertebrate oocytes must halt the cell cycle in meiosis II until sperm entry. Emi2 is...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1534580722006359
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU. Cyclin B3 implements timely vertebrate oocyte arrest for fertilization. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005.

Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells

Authors:
Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M
Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006
Epub:
Not Epub
Abstract:
Yamanaka factors are essential for establishing pluripotency in embryonic stem cells, but their function in multipotent stem...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1534580722006360
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M. Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006.

Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo

Authors:
Takebayashi-Suzuki K, Uchida M, Suzuki A
Citation:
Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print
Epub:
Not Epub
Abstract:
The vertebrate body is organized along the dorsal-ventral (DV) and anterior-posterior (AP) axes by the BMP and Wnt pathways,...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0006291X22013043
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Takebayashi-Suzuki K, Uchida M, Suzuki A. Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo. Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print.

Transcription factors interact with RNA to regulate genes

Authors:
Oksuz O, Henninger JE, Warneford-Thomson W, Zheng MM, Erb H, Overholt KJ, Hawken SW, Banani SF, Lauman R, Vancura A, Robertson AL, Hannett NM, Lee T, Zon LI, Bonasio R, Young RA
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.27.509776
Epub:
Not Epub
Abstract:
Transcription factors (TFs) orchestrate the gene expression programs that define each cell's identity. The canonical TF...
Link:
https://www.biorxiv.org/content/10.1101/2022.09.27.509776v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oksuz O, Henninger JE, Warneford-Thomson W, Zheng MM, Erb H, Overholt KJ, Hawken SW, Banani SF, Lauman R, Vancura A, Robertson AL, Hannett NM, Lee T, Zon LI, Bonasio R, Young RA. Transcription factors interact with RNA to regulate genes. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.27.509776.

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