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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Stimulating the autophagic-lysosomal axis enhances host defense against fungal infection in a zebrafish model of invasive Aspergillosis

Authors:
Forn-Cuní G, Welvaarts L, Stel FM, van den Hondel CJ, Arentshorst M, Ram AFJ, AH Meijer AH
Citation:
Autophagy. 2022;[Epub] doi:10.1080/15548627.2022.2090727
Epub:
Yes
Abstract:
The increasing prevalence of antifungal-resistant human pathogenic fungi, particularly azole-resistant Aspergillus fumigatus,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Forn-Cuní G, Welvaarts L, Stel FM, van den Hondel CJ, Arentshorst M, Ram AFJ, AH Meijer AH. Stimulating the autophagic-lysosomal axis enhances host defense against fungal infection in a zebrafish model of invasive Aspergillosis. Autophagy. 2022;[Epub] doi:10.1080/15548627.2022.2090727 .

VARS2 Depletion Leads to Activation of the Integrated Stress Response and Disruptions in Mitochondrial Fatty Acid Oxidation

Authors:
Kayvanpour E, Wisdom M, Lackner MK, Sedaghat-Hamedani F, Boeckel J-N, Müller M, Eghbalian R, Dudek J, Doroudgar S, Maack C, Frey N, Meder B
Citation:
Int J Mol Sci. 2022;23(13):7327. doi:10.3390/ijms23137327
Epub:
Not Epub
Abstract:
Mutations in mitochondrial aminoacyl-tRNA synthetases (mtARSs) have been reported in patients with mitochondriopathies: most...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kayvanpour E, Wisdom M, Lackner MK, Sedaghat-Hamedani F, Boeckel J-N, Müller M, Eghbalian R, Dudek J, Doroudgar S, Maack C, Frey N, Meder B. VARS2 Depletion Leads to Activation of the Integrated Stress Response and Disruptions in Mitochondrial Fatty Acid Oxidation. Int J Mol Sci. 2022;23(13):7327. doi:10.3390/ijms23137327.

Kinesin-13, a Motor Protein, is Regulated by Polo-like Kinase in Giardia lamblia

Authors:
Park EA, Kim J, Shin MY, Park SJ
Citation:
Korean J Parasitol. 2022 Jun;60(3):163-172. doi: 10.3347/kjp.2022.60.3.163. Epub 2022 Jun 30
Epub:
Not Epub
Abstract:
Kinesin-13 (Kin-13), a depolymerizer of microtubule (MT), has been known to affect the length of Giardia. Giardia Kin-13 (GlKin...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Park EA, Kim J, Shin MY, Park SJ. Kinesin-13, a Motor Protein, is Regulated by Polo-like Kinase in Giardia lamblia. Korean J Parasitol. 2022 Jun;60(3):163-172. doi: 10.3347/kjp.2022.60.3.163. Epub 2022 Jun 30.

Two HCN4 Channels Play Functional Roles in the Zebrafish Heart

Authors:
Liu J, Kasuya G, Zempo B, Nakajo K
Citation:
Front Physiol. 2022;13:901571. doi:10.3389/fphys.2022.901571
Epub:
Not Epub
Abstract:
The HCN4 channel is essential for heart rate regulation in vertebrates by generating pacemaker potentials in the sinoatrial...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu J, Kasuya G, Zempo B, Nakajo K. Two HCN4 Channels Play Functional Roles in the Zebrafish Heart. Front Physiol. 2022;13:901571. doi:10.3389/fphys.2022.901571.

Imaging and Analysis of Mouse Embryonic Whole Lung, Isolated Tissue, and Lineage-Labelled Cell Culture.

Authors:
Jones M, Bellusci S
Citation:
In: Bertoncello, I. (eds) Mouse Cell Culture. Methods in Molecular Biology. 2019;1940:109-27. Humana Press, New York, NY. doi:10.1007/978-1-4939-9086-3_8
Epub:
Not Epub
Abstract:
Research on lung development and disease frequently utilizes mouse models to conduct in vitro experiments. Such experiments...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse lung explants
Citation Extract:
Jones M, Bellusci S. Imaging and Analysis of Mouse Embryonic Whole Lung, Isolated Tissue, and Lineage-Labelled Cell Culture. . In: Bertoncello, I. (eds) Mouse Cell Culture. Methods in Molecular Biology. 2019;1940:109-27. Humana Press, New York, NY. doi:10.1007/978-1-4939-9086-3_8.

Retinoic acid control of pax8 during renal specification of Xenopus pronephros involves hox and meis3

Authors:
Durant-Vesga J, Suzuki N, Ochi H, Le Bouffant R, Eschstruth A, Ogino H, Umbhauer M, Riou J-F
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.21.496994
Epub:
Not Epub
Abstract:
Development of the Xenopus pronephros relies on renal precursors grouped at neurula stage into a specific region of dorso-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Durant-Vesga J, Suzuki N, Ochi H, Le Bouffant R, Eschstruth A, Ogino H, Umbhauer M, Riou J-F. Retinoic acid control of pax8 during renal specification of Xenopus pronephros involves hox and meis3. bioRxiv. 2022;[preprint] doi:10.1101/2022.06.21.496994.

Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss

Authors:
Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, Xie G, Liu D
Citation:
Cell. Mol. Life Sci. 2022:79(385). doi:10.1007/s00018-022-04410-2
Epub:
Not Epub
Abstract:
Hair cells play key roles in hearing and balance, and hair cell loss would result in hearing loss or vestibular dysfunction....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, Xie G, Liu D. Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cell. Mol. Life Sci. 2022:79(385). doi:10.1007/s00018-022-04410-2.

Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes

Authors:
Konjikusic MJ, Lee C, Yue Y, Shrestha BD, Nguimtsop AM, Horani A, Brody S, Prakash VN, Gray RS, Verhey KJ, Wallingford JB
Citation:
J Cell Sci. 2023 Mar 1;136(5):jcs259535. doi: 10.1242/jcs.259535. Epub 2022 Jun 22
Epub:
Not Epub
Abstract:
Most motile cilia have a stereotyped structure of nine microtubule outer doublets and a single central pair of microtubules....
Organism or Cell Type:
Xenopus
Citation Extract:
Konjikusic MJ, Lee C, Yue Y, Shrestha BD, Nguimtsop AM, Horani A, Brody S, Prakash VN, Gray RS, Verhey KJ, Wallingford JB. Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes. J Cell Sci. 2023 Mar 1;136(5):jcs259535. doi: 10.1242/jcs.259535. Epub 2022 Jun 22.

Mob4-dependent STRIPAK involves the chaperonin TRiC to coordinate myofibril and microtubule network growth

Authors:
Berger J, Berger S, Currie PD
Citation:
PLoS Genet. 2022;18(6):e1010287. doi:10.1371/journal.pgen.1010287
Epub:
Not Epub
Abstract:
Myofibrils of the skeletal muscle are comprised of sarcomeres that generate force by contraction when myosin-rich thick...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Berger J, Berger S, Currie PD. Mob4-dependent STRIPAK involves the chaperonin TRiC to coordinate myofibril and microtubule network growth. PLoS Genet. 2022;18(6):e1010287. doi:10.1371/journal.pgen.1010287.

Pacsin2 is required for endocytosis in the zebrafish pronephric tubule

Authors:
Morgan J, Yarwood R, Starborg T, Yan G, Lowe M
Citation:
Biol Open. 2022 Jun 15;11(6):bio059150. doi: 10.1242/bio.059150. Epub 2022 Jun 23
Epub:
Not Epub
Abstract:
Endocytosis mediates the cellular uptake of numerous molecules from the extracellular space and is a fundamentally important...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morgan J, Yarwood R, Starborg T, Yan G, Lowe M. Pacsin2 is required for endocytosis in the zebrafish pronephric tubule. Biol Open. 2022 Jun 15;11(6):bio059150. doi: 10.1242/bio.059150. Epub 2022 Jun 23.

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