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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling
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Citation:
Int J Mol Sci. 2022 Jul 17;23(14):7870. doi: 10.3390/ijms23147870 Epub:
Not Epub Abstract:
Acute kidney injury (AKI) is a common complication of severe human diseases, resulting in increased morbidity and mortality as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gessler S, Guthmann C, Schuler V, Lilienkamp M, Walz G, Yakulov TA. Control of Directed Cell Migration after Tubular Cell Injury by Nucleotide Signaling. Int J Mol Sci. 2022 Jul 17;23(14):7870. doi: 10.3390/ijms23147870. |
Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)
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Citation:
Exp Mol Med. 2022 Jul;54(7):973-987. doi: 10.1038/s12276-022-00801-4. Epub 2022 Jul 13 Epub:
Not Epub Abstract:
Despite well-known systemic immune reactions in peripheral trauma, little is known about their roles in posttraumatic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen XK, Kwan JS, Wong GT, Yi ZN, Ma AC, Chang RC. Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio). Exp Mol Med. 2022 Jul;54(7):973-987. doi: 10.1038/s12276-022-00801-4. Epub 2022 Jul 13. |
Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics
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Citation:
Sci Adv. 2022 Jul 15;8(28):eabm1890. doi: 10.1126/sciadv.abm1890. Epub 2022 Jul 13 Epub:
Not Epub Abstract:
T cells redirected to cancer cells either via a chimeric antigen receptor (CAR-T) or a bispecific molecule have been... Delivery Method:
Endo-Porter, Vivo-Morpholino Organism or Cell Type:
cell culture 293T, mice non-obese diabetic scid gamma NSG-SGM3 Citation Extract: Cripe TP, Hutzen B, Currier MA, Chen CY, Glaspell AM, Sullivan GC, Hurley JM, Deighen MR, Venkataramany AS, Mo X, Stanek JR, Miller AR, Wijeratne S, Magrini V, Mardis ER, Mendell JR, Chandler DS, Wang PY. Leveraging gene therapy to achieve long-term continuous or controllable expression of biotherapeutics. Sci Adv. 2022 Jul 15;8(28):eabm1890. doi: 10.1126/sciadv.abm1890. Epub 2022 Jul 13. |
Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice
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Citation:
Nucleic Acids Res. 2022 Aug 10:gkac641. doi: 10.1093/nar/gkac641. Online ahead of print Epub:
Yes Abstract:
Current therapies for Duchenne muscular dystrophy (DMD) use phosphorodiamidate morpholino oligomers (PMO) to induce exon... Delivery Method:
FORCE antigen-binding conjugate Organism or Cell Type:
mice Citation Extract: Desjardins CA, Yao M, Hall J, O'Donnell E, Venkatesan R, Spring S, Wen A, Hsia N, Shen P, Russo R, Lan B, Picariello T, Tang K, Weeden T, Zanotti S, Subramanian R, Ibraghimov-Beskrovnaya O. Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice. Nucleic Acids Res. 2022 Aug 10:gkac641. doi: 10.1093/nar/gkac641. Online ahead of print. |
AUF-1 knock down in mice overarches butyrate driven hypo-cholesteraemia by conjuring AUF-1-Dicer-1-miR122 hierarchy.
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.496022 Epub:
Not Epub Abstract:
This discourse probes the mechanistic molecular details of butyrate action in maintaining host-cholesterol balance. Hepatic... Delivery Method:
guanidinium-Morpholino GMO-PMO Organism or Cell Type:
mice Citation Extract: Das O, Kundu J, Ghosh A, Gautam A, Ghosh S, Chakraborty M, Masid A, Gauri SS, Mitra D, Dutta M, Mukherjee B, Sinha S, Bhaumik M. AUF-1 knock down in mice overarches butyrate driven hypo-cholesteraemia by conjuring AUF-1-Dicer-1-miR122 hierarchy. . bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.496022 . |
CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1
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Citation:
Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print Epub:
Not Epub Abstract:
Circular RNAs (circRNAs) play critical roles in clear cell renal cell carcinoma (ccRCC). However, their involvement in... Delivery Method:
electroporation Organism or Cell Type:
cell culture Citation Extract: Zhang MX, Wang JL, Mo CQ, Mao XP, Feng ZH, Li JY, Lin HS, Song HD, Xu QH, Wang YH, Lu J, Wei JH, Han H, Chen W, Mao HP, Luo JH, Chen ZH. CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1. Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print. |
Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression
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Citation:
Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623 Epub:
Not Epub Abstract:
Silencing the expression of the double homeobox 4 (DUX4) gene offers great potential for the treatment of facioscapulohumeral... Delivery Method:
Vivo-Morpholino i.p. injection Organism or Cell Type:
mice Citation Extract: Lu-Nguyen N, Dickson G, Malerba A, Popplewell L. Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression. Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623. |
Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish
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Citation:
Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7 Epub:
Not Epub Abstract:
Zebrafish irf2bp2a, an ortholog of human IRF2BP2, is specifically expressed in the developing liver at growth stage. As a multi... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan L, Gao S, Zhu J, Zhou J. Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish. Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7. |
Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina
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Citation:
Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611 Epub:
Not Epub Abstract:
Btg3-associated nuclear protein (Banp) was originally identified as a nuclear matrix-associated region (MAR)-binding protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Babu S, Takeuchi Y, Masai I. Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina. Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611. |
Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1
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Citation:
Biochem Biophys Res Commun. 2022 Jul 31;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Online ahead of print Epub:
Not Epub Abstract:
Autosomal recessive primary microcephaly (MCPH) is a rare congenital disorder characterized by a below average brain volume at... Organism or Cell Type:
zebrafish Citation Extract: Apridita Sebastian W, Shiraishi H, Shimizu N, Umeda R, Lai S, Ikeuchi M, Morisaki I, Yano S, Yoshimura A, Hanada R, Hanada T. Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1. Biochem Biophys Res Commun. 2022 Jul 31;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Online ahead of print. |