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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A Cell-Penetrating Peptide Enhances Delivery and Efficacy of Phosphorodiamidate Morpholino Oligomers in mdx Mice
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Citation:
Mol Ther Nucleic Acids. 2022;[Epub ahead of print] doi:10.1016/j.omtn.2022.08.019 Epub:
Yes Abstract:
Antisense RNA technology is a strategy for the treatment of Duchenne muscular dystrophy (DMD), a progressive and universally... Citation Extract: Gan L, Wu LCL, Wood JA, Yao M, Treleaven CM, Estrella NL, Wentworth BM, Hanson GL, Passini MA. A Cell-Penetrating Peptide Enhances Delivery and Efficacy of Phosphorodiamidate Morpholino Oligomers in mdx Mice. Mol Ther Nucleic Acids. 2022;[Epub ahead of print] doi:10.1016/j.omtn.2022.08.019. |
Simultaneous crosslinking of CD20 and CD38 receptors by drug-free macromolecular therapeutics enhances B cell apoptosis in vitro and in vivo
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Citation:
J Control Release. 2022 Aug 26:S0168-3659(22)00552-1. doi: 10.1016/j.jconrel.2022.08.045. Online ahead of print Epub:
Yes Abstract:
Drug-Free Macromolecular Therapeutics (DFMT) is a new paradigm in macromolecular therapeutics that induces apoptosis in target... Organism or Cell Type:
cell culture: Raji (CD20+; CD38+) B cells; xenograft mouse Citation Extract: Tommy Gambles M, Li J, Christopher Radford D, Sborov D, Shami P, Yang J, Kopeček J. Simultaneous crosslinking of CD20 and CD38 receptors by drug-free macromolecular therapeutics enhances B cell apoptosis in vitro and in vivo. J Control Release. 2022 Aug 26:S0168-3659(22)00552-1. doi: 10.1016/j.jconrel.2022.08.045. Online ahead of print. |
Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing
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Citation:
Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2207956119. doi: 10.1073/pnas.2207956119. Epub 2022 Aug 29 Epub:
Not Epub Abstract:
Recent advances in drug development have seen numerous successful clinical translations using synthetic antisense... Delivery Method:
lipofectin Organism or Cell Type:
cell culture: murine myotubes Citation Extract: Le BT, Paul S, Jastrzebska K, Langer H, Caruthers MH, Veedu RN. Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2207956119. doi: 10.1073/pnas.2207956119. Epub 2022 Aug 29. |
Design and Microinjection of Morpholino Antisense Oligonucleotides and mRNA into Zebrafish Embryos to Elucidate Specific Gene Function in Heart Development
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Citation:
J Vis Exp. 2022 Aug 9;(186). doi: 10.3791/63324 Epub:
Not Epub Abstract:
The morpholino oligomer-based knockdown system has been used to identify the function of various gene products through loss or... Link:
Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zakaria ZZ, Eisa-Beygi S, Benslimane FM, Ramchandran R, Yalcin HC. Design and Microinjection of Morpholino Antisense Oligonucleotides and mRNA into Zebrafish Embryos to Elucidate Specific Gene Function in Heart Development. J Vis Exp. 2022 Aug 9;(186). doi: 10.3791/63324. |
Antisense Morpholino-Based In Vitro Correction of a Pseudoexon-Generating Variant in the SGCB Gene
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Citation:
Int J Mol Sci. 2022;23(17):9817. doi:10.3390/ijms23179817 Epub:
Not Epub Abstract:
Limb-girdle muscular dystrophies (LGMD) are clinically and genetically heterogenous presentations displaying predominantly... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
human induced pluripotent stem cells (iPSC) Citation Extract: Magri F, Zanotti S, Salani S, Fortunato F, Ciscato P, Gerevini S, Maggi L, Sciacco M, Moggio M, Corti S, Bresolin N, Comi GP, Ronchi D. Antisense Morpholino-Based In Vitro Correction of a Pseudoexon-Generating Variant in the SGCB Gene. Int J Mol Sci. 2022;23(17):9817. doi:10.3390/ijms23179817. |
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2
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Citation:
Matrix Biol. 2022 Aug 22:S0945-053X(22)00103-2. doi: 10.1016/j.matbio.2022.08.009. Online ahead of print Epub:
Yes Abstract:
Hemicentins are large proteins of the extracellular matrix that belong to the fibulin family and play pivotal roles during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang JL, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M. Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2. Matrix Biol. 2022 Aug 22:S0945-053X(22)00103-2. doi: 10.1016/j.matbio.2022.08.009. Online ahead of print. |
Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish
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Citation:
Cells. 2022 Aug 15;11(16):2527. doi: 10.3390/cells11162527 Epub:
Not Epub Abstract:
Endothelial cells (ECs) and neurons share a number of common signaling pathways and molecular mediators to orchestrate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sheng J, Jiang B, Shi R, Shi L, Liu D. Sema4C Is Required for Vascular and Primary Motor Neuronal Patterning in Zebrafish. Cells. 2022 Aug 15;11(16):2527. doi: 10.3390/cells11162527. |
Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury
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Citation:
Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318 Epub:
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Background: Lysine demethylase 4C (KDM4C) is a nuclear protein that is essential for histone modification and acts as an... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pan HC, Chen YH, Fang WC, Wu VC, Sun CY. Essential Roles of the Histone Demethylase KDM4C in Renal Development and Acute Kidney Injury. Int J Mol Sci. 2022 Aug 18;23(16):9318. doi: 10.3390/ijms23169318. |
Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis
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Citation:
Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250 Epub:
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The orphan insulin receptor-related receptor (IRR) encoded by insrr gene is the third member of the insulin receptor family,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Korotkova DD, Gantsova EA, Goryashchenko AS, Eroshkin FM, Serova OV, Sokolov AS, Sharko F, Zhenilo SV, Martynova NY, Petrenko AG, Zaraisky AG, Deyev IE. Insulin Receptor-Related Receptor Regulates the Rate of Early Development in Xenopus laevis. Int J Mol Sci. 2022 Aug 17;23(16):9250. doi: 10.3390/ijms23169250. |
Functions of block of proliferation 1 during anterior development in Xenopus laevis
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Citation:
PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022 Epub:
Not Epub Abstract:
Block of proliferation 1 (Bop1) is a nucleolar protein known to be necessary for the assembly of the 60S subunit of ribosomes.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gärtner C, Meßmer A, Dietmann P, Kühl M, Kühl SJ. Functions of block of proliferation 1 during anterior development in Xenopus laevis. PLoS One. 2022 Aug 25;17(8):e0273507. doi: 10.1371/journal.pone.0273507. eCollection 2022. |