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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
N-methyl-N-nitrosourea induces zebrafish anomalous angiogenesis through Wnt/β-catenin pathway
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Citation:
Ecotoxicol Environ Saf. 2022 May 24;239:113674. doi: 10.1016/j.ecoenv.2022.113674. Online ahead of print Epub:
Not Epub Abstract:
N-methyl-N-nitrosourea (MNU) is a prevalent environmental carcinogen, which leads to tumors in various organs in animal models... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fu S, Tan R, Feng Y, Yu P, Mo Y, Xiao W, Wang S, Zhang J. N-methyl-N-nitrosourea induces zebrafish anomalous angiogenesis through Wnt/β-catenin pathway. Ecotoxicol Environ Saf. 2022 May 24;239:113674. doi: 10.1016/j.ecoenv.2022.113674. Online ahead of print. |
Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development
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Citation:
Int J Mol Sci. 2022 May 20;23(10):5712. doi: 10.3390/ijms23105712 Epub:
Not Epub Abstract:
Numerous studies have focused on the molecular signaling pathways that govern the development and growth of lymphatics in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xu W, Nelson-Maney NP, Bálint L, Kwon HB, Davis RB, Dy DCM, Dunleavey JM, St Croix B, Caron KM. Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development. Int J Mol Sci. 2022 May 20;23(10):5712. doi: 10.3390/ijms23105712. |
U1 snRNP regulates early spliceosome assembly by disrupting the interaction between SR proteins and the pre-mRNA
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.01.470860 Epub:
Not Epub Abstract:
The pre-mRNA features that define the splice signals at or near exon-intron junctions for assembly of the early spliceosome are... Organism or Cell Type:
cell culture: HeLa Citation Extract: Saha K, Ghosh G. U1 snRNP regulates early spliceosome assembly by disrupting the interaction between SR proteins and the pre-mRNA. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.01.470860. |
Transcription factors that specify cell fate activate cell cycle regulator genes to determine cell numbers in ascidian larval tissues
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.05.16.492211 Epub:
Not Epub Abstract:
In animal development, most cell types stop dividing before terminal differentiation; thus, cell cycle control is tightly... Delivery Method:
microinjection Organism or Cell Type:
Ciona savignyi (ascidian) Citation Extract: Kobayashi K, Tokuoka M, Sato H, Ariyoshi M, Kawahara S, Fujiwara S, Kishimoto T, Satou Y. Transcription factors that specify cell fate activate cell cycle regulator genes to determine cell numbers in ascidian larval tissues. bioRxiv. 2022;[preprint] doi:10.1101/2022.05.16.492211 . |
RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer
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Citation:
Nat Commun. 2022 May 19;13(1):2791. doi: 10.1038/s41467-022-30489-z Epub:
Not Epub Abstract:
Tumour cell plasticity is a major barrier to the efficacy of targeted cancer therapies but the mechanisms that mediate it are... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse intestine cells Citation Extract: Hall AE, Pohl SÖ, Cammareri P, Aitken S, Younger NT, Raponi M, Billard CV, Carrancio AB, Bastem A, Freile P, Haward F, Adams IR, Caceres JF, Preyzner P, von Kriegsheim A, Dunlop MG, Din FV, Myant KB. RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer. Nat Commun. 2022 May 19;13(1):2791. doi: 10.1038/s41467-022-30489-z. |
Cachd1 is a novel Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.05.16.492129 Epub:
Not Epub Abstract:
Neurons on left and right sides of the nervous system frequently show asymmetric properties but how these differences arise is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Powell GT, Zhao Y, Faro A, Stickney H, Novellasdemunt L, Henriques P, Gestri G, White ER, Ren J, Lu W, Young RM, Hawkins TA, Cavodeassi F, Schwarz Q, Dreosti E, Raible DW, Li VSW, Wright GJ, Jones EY, Wilson SW. Cachd1 is a novel Frizzled- and LRP6-interacting protein required for neurons to acquire left-right asymmetric character. bioRxiv. 2022;[preprint] doi:10.1101/2022.05.16.492129 . |
Peripheral NOD-like receptor deficient inflammatory macrophages trigger neutrophil infiltration into the brain disrupting daytime locomotion
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Citation:
Commun Biol. 2022 May 16;5(1):464. doi: 10.1038/s42003-022-03410-z Epub:
Not Epub Abstract:
Inflammation is known to disrupt normal behavior, yet the underlying neuroimmune interactions remain elusive. Here, we... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kwon V, Cai P, Dixon CT, Hamlin V, Spencer CG, Rojas AM, Hamilton M, Shiau CE. Peripheral NOD-like receptor deficient inflammatory macrophages trigger neutrophil infiltration into the brain disrupting daytime locomotion. Commun Biol. 2022 May 16;5(1):464. doi: 10.1038/s42003-022-03410-z. |
The Cytoskeletal Protein Zyxin Inhibits Retinoic Acid Signaling by Destabilizing the Maternal mRNA of the RXRγ Nuclear Receptor
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Citation:
Inter J Mol Sci. 2022;23(10):5627. doi:10.3390/ijms23105627 Epub:
Not Epub Abstract:
Zyxin is an LIM-domain-containing protein that regulates the assembly of F-actin filaments in cell contacts. Additionally, as a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Parshina EA, Orlov EE, Zaraisky AG, Martynova NY. The Cytoskeletal Protein Zyxin Inhibits Retinoic Acid Signaling by Destabilizing the Maternal mRNA of the RXRγ Nuclear Receptor. Inter J Mol Sci. 2022;23(10):5627. doi:10.3390/ijms23105627. |
BDNF signaling in Hebbian and Stentian structural plasticity in the developing visual system
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.10.07.463583 Epub:
Not Epub Abstract:
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural... Delivery Method:
ocular injection then electroporation Organism or Cell Type:
Xenopus laevis Citation Extract: Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES. BDNF signaling in Hebbian and Stentian structural plasticity in the developing visual system. bioRxiv. 2021;[preprint] doi:10.1101/2021.10.07.463583 . |
Transmembrane Protein 184A and Syndecan-4 function in the same pathway to promote angiogenesis
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Citation:
FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.L8077 Epub:
Not Epub Abstract:
Morpholino (MO) knockdown (KD) of the novel vascular heparin receptor, Transmembrane protein 184A (TMEM184A), increases... Delivery Method:
injection Organism or Cell Type:
zebrafish Citation Extract: Altenburg LM, O'Toole RA, Ciabattoni GO, Papov IV, Pasch LM, Maslonka BE, Lowe-Krentz LJ. Transmembrane Protein 184A and Syndecan-4 function in the same pathway to promote angiogenesis. FASEB J. 2022;[Epub] doi:10.1096/fasebj.2022.36.S1.L8077. |