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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD

Authors:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L
Citation:
Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006
Epub:
Not Epub
Abstract:
BACKGROUND: Many psychiatric disorders share working memory (WM) impairment phenotype, yet the genetic causes remain unclear....
Link:
https://www.bpsgos.org/article/S2667-1743(22)00099-4/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L. RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD. Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006.

Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches

Authors:
Bina P, Taneyhill LA
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039
Epub:
Not Epub
Abstract:
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.506039v1
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bina P, Taneyhill LA. Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039 .

A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly

Authors:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P
Citation:
Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727
Epub:
Not Epub
Abstract:
Microcephaly presents in neurodevelopmental disorders with multiple aetiologies, including bi-allelic mutation in TUBGCP2, a...
Link:
https://www.mdpi.com/2073-4409/11/17/2727
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P. A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly. Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727.

eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?

Authors:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M
Citation:
Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075
Epub:
Not Epub
Abstract:
The eukaryotic initiation factor 4E binding protein (4E-BP) family is involved in translational control of cell proliferation...
Link:
https://www.mdpi.com/1422-0067/23/17/10075
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Born LI, Andree T, Frank S, Hübner J, Link S, Langheine M, Charlet A, Esser JS, Brehm R, Moser M. eif4ebp3l-A New Affector of Zebrafish Angiogenesis and Heart Regeneration?. Int J Mol Sci. 2022 Sep 3;23(17):10075. doi: 10.3390/ijms231710075.

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

Authors:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME
Citation:
Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3
Epub:
Not Epub
Abstract:
The sideroblastic anemias are a heterogeneous group of congenital and acquired hematological disorders whose morphological...
Link:
https://www.nature.com/articles/ng.359
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guernsey DL, Jiang H, Campagna DR, Evans SC, Ferguson M, Kellogg MD, Lachance M, Matsuoka M, Nightingale M, Rideout A, Saint-Amant L, Schmidt PJ, Orr A, Bottomley SS, Fleming MD, Ludman M, Dyack S, Fernandez CV, Samuels ME. Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia. Nat Genet. 2009 Jun;41(6):651-3. doi: 10.1038/ng.359. Epub 2009 May 3.

Neuromuscular NMDA receptors regulate developmental synaptic depletion

Authors:
Joy E
Citation:
Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442
Epub:
Not Epub
Abstract:
[no abstract]
Link:
https://www.iomcworld.org/open-access/neuromuscular-nmda-receptors-regulate-developmental-synaptic-depletion.pdf
Delivery Method:
Vivo-Morpholino
Citation Extract:
Joy E. Neuromuscular NMDA receptors regulate developmental synaptic depletion. Mult Scler. 2022;9(5):442 doi:10.35248/2376-0389.22.9.5.442.

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis

Authors:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X
Citation:
Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30
Epub:
Not Epub
Abstract:
The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa) remains controversial. Previously, we...
Link:
https://www.nature.com/articles/s12276-022-00837-6
Delivery Method:
exosomes
Organism or Cell Type:
mice BALB/c
Citation Extract:
Gan J, Liu S, Zhang Y, He L, Bai L, Liao R, Zhao J, Guo M, Jiang W, Li J, Li Q, Mu G, Wu Y, Wang X, Zhang X, Zhou D, Lv H, Wang Z, Zhang Y, Qian C, Feng M, Chen H, Meng Q, Huang X. MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis. Exp Mol Med. 2022 Aug;54(8):1290-1305. doi: 10.1038/s12276-022-00837-6. Epub 2022 Aug 30.

A lysosomal regulatory circuit essential for the development and function of microglia

Authors:
Iyer H, Shen K, Meireles AM, Talbot WS
Citation:
Sci Adv. 2022 Sep 2;8(35):eabp8321. doi: 10.1126/sciadv.abp8321. Epub 2022 Aug 31
Epub:
Not Epub
Abstract:
As the primary phagocytic cells of the central nervous system, microglia exquisitely regulate their lysosomal activity to...
Link:
https://www.science.org/doi/10.1126/sciadv.abp8321
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer H, Shen K, Meireles AM, Talbot WS. A lysosomal regulatory circuit essential for the development and function of microglia. Sci Adv. 2022 Sep 2;8(35):eabp8321. doi: 10.1126/sciadv.abp8321. Epub 2022 Aug 31.

Optical Control of MicroRNA Function in Zebrafish Embryos

Authors:
Brown W, Bardhan A, Darrah K, Tsang M, Deiters A
Citation:
J Am Chem Soc. 2022 Sep 8. doi: 10.1021/jacs.2c04479. Online ahead of print
Epub:
Yes
Abstract:
MicroRNAs play crucial and dynamic roles in vertebrate development and diseases. Some, like miR-430, are highly expressed...
Link:
https://pubs.acs.org/doi/10.1021/jacs.2c04479
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brown W, Bardhan A, Darrah K, Tsang M, Deiters A. Optical Control of MicroRNA Function in Zebrafish Embryos. J Am Chem Soc. 2022 Sep 8. doi: 10.1021/jacs.2c04479. Online ahead of print.

Hemifacial microsomia is linked a rare homozygous variant V162I in FRK and validated in zebrafish

Authors:
Xiong J, Wang X, Fan C, Yan J, Zhu J, Cai T
Citation:
Oral Dis. 2022 Sep 7. doi: 10.1111/odi.14372. Online ahead of print
Epub:
Yes
Abstract:
Objectives: Hemifacial microsomia (HFM) is a common birth defect involving the first and second branchial arch derivatives....
Link:
https://onlinelibrary.wiley.com/doi/10.1111/odi.14372
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong J, Wang X, Fan C, Yan J, Zhu J, Cai T . Hemifacial microsomia is linked a rare homozygous variant V162I in FRK and validated in zebrafish. Oral Dis. 2022 Sep 7. doi: 10.1111/odi.14372. Online ahead of print.

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