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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish
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Citation:
Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229 Epub:
Not Epub Abstract:
Hereditary hearing loss is a highly genetically heterogeneous disorder. More than 150 genes have been identified to link to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li Y, Ning G, Kang B, Zhu J, Wang X-Y, Wang Q, Cai T. A novel recessive mutation in OXR1 is identified in patient with hearing loss recapitulated by the knockdown zebrafish. Hum Molec Genet. 2022;ddac229. doi:10.1093/hmg/ddac229. |
Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish
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Citation:
Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7 Epub:
Not Epub Abstract:
Clockwise rotation of the primitive heart tube, a process regulated by restricted left-sided Nodal signaling, is the first... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kidokoro H, Saijoh Y, Schoenwolf GC. Nodal signaling regulates asymmetric cellular behaviors, driving clockwise rotation of the heart tube in zebrafish. Commun Biol. 2022;5:996. doi:10.1038/s42003-022-03826-7. |
Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish
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Citation:
Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6 Epub:
Not Epub Abstract:
Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Niescierowicz K, Pryszcz L, Navarrete C, Tralle E, Sulej A, Abu NK, Kasprzyk ME, Misztal K, Pateria A, Pakuła A, Bochtler M, Winata C. Adar-mediated A-to-I editing is required for embryonic patterning and innate immune response regulation in zebrafish. Nat Commun. 2022;13:5520. doi:10.1038/s41467-022-33260-6. |
Single-cell transcriptomics identifies conserved regulators of neuroglandular lineages
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Citation:
Cell Rep. 2022;40(12):111370. doi:j.celrep.2022.111370 Epub:
Not Epub Abstract:
Communication in bilaterian nervous systems is mediated by electrical and secreted signals; however, the evolutionary origin... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Steger J, Cole AG, Denner A, Lebedeva T, Genikhovich G, Ries A, Reischl R, Taudes E, Lassnig M, Technau U. Single-cell transcriptomics identifies conserved regulators of neuroglandular lineages. Cell Rep. 2022;40(12):111370. doi:j.celrep.2022.111370. |
Dynamic Fibronectin Assembly and Remodeling by Leader Neural Crest Cells Prevents Jamming in Collective Cell Migration
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Citation:
arXiv. 2022;[preprint] doi:10.48550/arXiv.2209.07794 Epub:
Not Epub Abstract:
Collective cell migration plays an essential role in vertebrate development, yet the extent to which dynamically changing... Delivery Method:
injection Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Martinson WD, McLennan R, Teddy JM, McKinney MC, Davidson LA, Baker RE, Byrne HM, Kulesa PM, Maini PK. Dynamic Fibronectin Assembly and Remodeling by Leader Neural Crest Cells Prevents Jamming in Collective Cell Migration. arXiv. 2022;[preprint] doi:10.48550/arXiv.2209.07794. |
Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio
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Citation:
J Exp Biol. 2022;jeb.244279. doi:10.1242/jeb.244279 Epub:
Not Epub Abstract:
Ammonia excretion in fish excretory epithelia is a complex interplay of multiple membrane transport proteins and mechanisms.... Organism or Cell Type:
zebrafish Citation Extract: Zhouyao H, Zimmer AM, Fehsenfeld S, Liebenstein T, Richter DO, Begemann G, Eck P, Perry SF, Weihrauch D. Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio. J Exp Biol. 2022;jeb.244279. doi:10.1242/jeb.244279. |
Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue
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Citation:
Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0 Epub:
Not Epub Abstract:
In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage, dysregulation of repair, fibro-fatty... Organism or Cell Type:
mice, human Citation Extract: Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC. Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue. Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0. |
De novo disruptive heterozygous MMP21 variants are potential predisposing genetic risk factors in Chinese Han heterotaxy children
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Citation:
Hum Genomics. 2022;16:41. doi:10.1186/s40246-022-00409-9 Epub:
Not Epub Abstract:
Background: Heterotaxy syndrome (HTX) is caused by aberrant left-right patterning early in embryonic development, which results... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Qin X-j, Xu M-m, Ye J-j, Niu Y-w, Wu Y-r, Xu R, Li F, Fu Q-h, Chen S, Sun K, Xu Y-j. De novo disruptive heterozygous MMP21 variants are potential predisposing genetic risk factors in Chinese Han heterotaxy children. Hum Genomics. 2022;16:41. doi:10.1186/s40246-022-00409-9. |
RIOK3 and Its Alternatively Spliced Isoform Have Disparate Roles in the Innate Immune Response to Rift Valley Fever Virus (MP12) Infection
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Citation:
Viruses. 2022;14(9):2064. doi:10.3390/v14092064 Epub:
Not Epub Abstract:
Rift Valley fever virus (RVFV) is a pathogenic human and livestock RNA virus that poses a significant threat to public health... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK 293 Citation Extract: Bisom TC, White LA, Lanchy J-M, Lodmell JS. RIOK3 and Its Alternatively Spliced Isoform Have Disparate Roles in the Innate Immune Response to Rift Valley Fever Virus (MP12) Infection. Viruses. 2022;14(9):2064. doi:10.3390/v14092064 . |
Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.14.507817 Epub:
Not Epub Abstract:
After fertilization, maternally contributed factors to the egg initiate the transition to pluripotency to give rise to... Organism or Cell Type:
Xenopus laevis Citation Extract: Phelps WA, Hurton MD, Ayers TN, Carlson AE, Rosenbaum JC, Lee MT. Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.14.507817. |