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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice
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Citation:
Nucleic Acids Res. 2022 Aug 10:gkac641. doi: 10.1093/nar/gkac641. Online ahead of print Epub:
Yes Abstract:
Current therapies for Duchenne muscular dystrophy (DMD) use phosphorodiamidate morpholino oligomers (PMO) to induce exon... Delivery Method:
FORCE antigen-binding conjugate Organism or Cell Type:
mice Citation Extract: Desjardins CA, Yao M, Hall J, O'Donnell E, Venkatesan R, Spring S, Wen A, Hsia N, Shen P, Russo R, Lan B, Picariello T, Tang K, Weeden T, Zanotti S, Subramanian R, Ibraghimov-Beskrovnaya O. Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice. Nucleic Acids Res. 2022 Aug 10:gkac641. doi: 10.1093/nar/gkac641. Online ahead of print. |
AUF-1 knock down in mice overarches butyrate driven hypo-cholesteraemia by conjuring AUF-1-Dicer-1-miR122 hierarchy.
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.496022 Epub:
Not Epub Abstract:
This discourse probes the mechanistic molecular details of butyrate action in maintaining host-cholesterol balance. Hepatic... Delivery Method:
guanidinium-Morpholino GMO-PMO Organism or Cell Type:
mice Citation Extract: Das O, Kundu J, Ghosh A, Gautam A, Ghosh S, Chakraborty M, Masid A, Gauri SS, Mitra D, Dutta M, Mukherjee B, Sinha S, Bhaumik M. AUF-1 knock down in mice overarches butyrate driven hypo-cholesteraemia by conjuring AUF-1-Dicer-1-miR122 hierarchy. . bioRxiv. 2022;[preprint] doi:10.1101/2022.06.13.496022 . |
CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1
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Citation:
Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print Epub:
Not Epub Abstract:
Circular RNAs (circRNAs) play critical roles in clear cell renal cell carcinoma (ccRCC). However, their involvement in... Delivery Method:
electroporation Organism or Cell Type:
cell culture Citation Extract: Zhang MX, Wang JL, Mo CQ, Mao XP, Feng ZH, Li JY, Lin HS, Song HD, Xu QH, Wang YH, Lu J, Wei JH, Han H, Chen W, Mao HP, Luo JH, Chen ZH. CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1. Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print. |
Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression
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Citation:
Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623 Epub:
Not Epub Abstract:
Silencing the expression of the double homeobox 4 (DUX4) gene offers great potential for the treatment of facioscapulohumeral... Delivery Method:
Vivo-Morpholino i.p. injection Organism or Cell Type:
mice Citation Extract: Lu-Nguyen N, Dickson G, Malerba A, Popplewell L. Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression. Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623. |
Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish
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Citation:
Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7 Epub:
Not Epub Abstract:
Zebrafish irf2bp2a, an ortholog of human IRF2BP2, is specifically expressed in the developing liver at growth stage. As a multi... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan L, Gao S, Zhu J, Zhou J. Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish. Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7. |
Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina
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Citation:
Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611 Epub:
Not Epub Abstract:
Btg3-associated nuclear protein (Banp) was originally identified as a nuclear matrix-associated region (MAR)-binding protein... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Babu S, Takeuchi Y, Masai I. Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina. Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611. |
Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1
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Citation:
Biochem Biophys Res Commun. 2022 Jul 31;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Online ahead of print Epub:
Not Epub Abstract:
Autosomal recessive primary microcephaly (MCPH) is a rare congenital disorder characterized by a below average brain volume at... Organism or Cell Type:
zebrafish Citation Extract: Apridita Sebastian W, Shiraishi H, Shimizu N, Umeda R, Lai S, Ikeuchi M, Morisaki I, Yano S, Yoshimura A, Hanada R, Hanada T. Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1. Biochem Biophys Res Commun. 2022 Jul 31;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Online ahead of print. |
Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish
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Citation:
Neural Regen Res. 2023 Feb;18(2):445-450. doi: 10.4103/1673-5374.346550 Epub:
Not Epub Abstract:
The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development. However, its... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Song K, Lin Z, Cao L, Lu B, Chen Y, Zhang S, Lu J, Xu H. Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish. Neural Regen Res. 2023 Feb;18(2):445-450. doi: 10.4103/1673-5374.346550. |
Quantification of Idua Enzymatic Activity Combined with Observation of Phenotypic Change in Zebrafish Embryos Provide a Preliminary Assessment of Mutated idua Correlated with Mucopolysaccharidosis Type I
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Citation:
J Pers Med. 2022 Jul 23;12(8):1199. doi: 10.3390/jpm12081199 Epub:
Not Epub Abstract:
Mucopolysaccharidosis type I (MPS I) is an inherited autosomal recessive disease resulting from mutation of the α-l-Iduronidase... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin CY, Lin HY, Chuang CK, Zhang PH, Tu YR, Lin SP, Tsai HJ. Quantification of Idua Enzymatic Activity Combined with Observation of Phenotypic Change in Zebrafish Embryos Provide a Preliminary Assessment of Mutated idua Correlated with Mucopolysaccharidosis Type I. J Pers Med. 2022 Jul 23;12(8):1199. doi: 10.3390/jpm12081199. |
The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development
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Citation:
J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029 Epub:
Not Epub Abstract:
Mandibulofacial dysostosis (MFD) is a human congenital disorder characterized by hypoplastic neural-crest-derived craniofacial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Park BY, Tachi-Duprat M, Ihewulezi C, Devotta A, Saint-Jeannet JP. The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development. J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029. |