You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Simultaneous imaging of calcium and contraction in the beating heart of zebrafish larvae

Authors:
Salgado-Almario J, Vicente M, Molina Y, Martinez-Sielva A, Vincent P, Domingo B, Llopis J
Citation:
Theranostics. 2022 Jan 1;12(3):1012-1029. doi: 10.7150/thno.64734. eCollection 2022
Epub:
Not Epub
Abstract:
In vivo models of cardiac function maintain the complex relationship of cardiomyocytes with other heart cells, as well as the...
Link:
https://www.thno.org/v12p1012.htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Salgado-Almario J, Vicente M, Molina Y, Martinez-Sielva A, Vincent P, Domingo B, Llopis J. Simultaneous imaging of calcium and contraction in the beating heart of zebrafish larvae. Theranostics. 2022 Jan 1;12(3):1012-1029. doi: 10.7150/thno.64734. eCollection 2022.

Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans

Authors:
Forst CV, Martin-Sancho L, Tripathi S, Wang G, Dos Anjos Borges LG, Wang M, Geber A, Lashua L, Ding T, Zhou X, Carter CE, Metreveli G, Rodriguez-Frandsen A, Urbanowski MD, White KM, Stein DA, Moulton H, Chanda SK, Pache L, Shaw ML, Ross TM, Ghedin E, García-Sastre A, Zhang B
Citation:
Sci Adv. 2022 Oct 7;8(40):eabm5859. doi: 10.1126/sciadv.abm5859. Epub 2022 Oct 5
Epub:
Not Epub
Abstract:
Molecular responses to influenza A virus (IAV) infections vary between mammalian species. To identify conserved and species-...
Link:
https://www.science.org/doi/10.1126/sciadv.abm5859
Delivery Method:
peptide-linked
Organism or Cell Type:
mice
Citation Extract:
Forst CV, Martin-Sancho L, Tripathi S, Wang G, Dos Anjos Borges LG, Wang M, Geber A, Lashua L, Ding T, Zhou X, Carter CE, Metreveli G, Rodriguez-Frandsen A, Urbanowski MD, White KM, Stein DA, Moulton H, Chanda SK, Pache L, Shaw ML, Ross TM, Ghedin E, García-Sastre A, Zhang B. Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans. Sci Adv. 2022 Oct 7;8(40):eabm5859. doi: 10.1126/sciadv.abm5859. Epub 2022 Oct 5.

Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo

Authors:
Moore RE, Pop S, Alleyne C, Clarke JDW
Citation:
EMBO Rep. 2022 Oct 4:e52493. doi: 10.15252/embr.202152493. Online ahead of print
Epub:
Not Epub
Abstract:
Our understanding of the cell behaviours and cytoskeletal requirements of axon formation is largely derived from in vitro...
Link:
https://www.embopress.org/doi/full/10.15252/embr.202152493
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore RE, Pop S, Alleyne C, Clarke JDW. Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo. EMBO Rep. 2022 Oct 4:e52493. doi: 10.15252/embr.202152493. Online ahead of print.

Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy

Authors:
Becette OB, Marino JP, Brinson RG
Citation:
Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print
Epub:
Yes
Abstract:
Purpose: Antisense oligonucleotide (ASO) therapeutics are an emerging class of biopharmaceuticals to treat and prevent diseases...
Link:
https://pubmed.ncbi.nlm.nih.gov/36195820/
Citation Extract:
Becette OB, Marino JP, Brinson RG. Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy. Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print.

Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development

Authors:
Williams AL, Bohnsack BL
Citation:
J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042
Epub:
Not Epub
Abstract:
Most cases of Stickler syndrome are due to autosomal-dominant COL2A1 gene mutations leading to abnormal type II collagen....
Link:
https://www.mdpi.com/2221-3759/10/4/42
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Williams AL, Bohnsack BL. Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development. J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042.

An FGF Timer for Zygotic Genome Activation

Authors:
Treen N, Chavarria E, Weaver CJ, Brangwynne CF, Levine M
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450
Epub:
Not Epub
Abstract:
Zygotic genome activation has been extensively studied in a variety of systems including flies, frogs, and mammals. However,...
Link:
https://www.biorxiv.org/content/10.1101/2022.10.01.510450v1
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Treen N, Chavarria E, Weaver CJ, Brangwynne CF, Levine M. An FGF Timer for Zygotic Genome Activation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450.

RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification

Authors:
Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME
Citation:
Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600
Epub:
Not Epub
Abstract:
While neural crest development is known to be transcriptionally controlled via sequential activation of gene regulatory...
Link:
https://elifesciences.org/articles/63600
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600.

Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos

Authors:
Kumar A, Rhee M
Citation:
Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print
Epub:
Yes
Abstract:
Background: Molecular networks associated with dopaminergic (DA) neurogenesis remain undefined within mammalian models. To...
Link:
https://link.springer.com/article/10.1007/s13258-022-01317-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumar A, Rhee M. Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos. Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print.

Cyclin B3 implements timely vertebrate oocyte arrest for fertilization

Authors:
Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU
Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005
Epub:
Not Epub
Abstract:
To ensure successful offspring ploidy, vertebrate oocytes must halt the cell cycle in meiosis II until sperm entry. Emi2 is...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1534580722006359
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU. Cyclin B3 implements timely vertebrate oocyte arrest for fertilization. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005.

Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells

Authors:
Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M
Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006
Epub:
Not Epub
Abstract:
Yamanaka factors are essential for establishing pluripotency in embryonic stem cells, but their function in multipotent stem...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1534580722006360
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M. Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006.

Pages