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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336 Epub:
Not Epub Abstract:
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Jiang L, Wang H, Wen Z, Yao Z, Wu Z. Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336. |
The Shape of the Jaw-Zebrafish Col11a1a Regulates Meckel's Cartilage Morphogenesis and Mineralization
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Citation:
J Dev Biol. 2022 Sep 22;10(4):40. doi: 10.3390/jdb10040040 Epub:
Not Epub Abstract:
The expression of the col11a1a gene is essential for normal skeletal development, affecting both cartilage and bone. Loss of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reeck JC, Oxford JT. The Shape of the Jaw-Zebrafish Col11a1a Regulates Meckel's Cartilage Morphogenesis and Mineralization. J Dev Biol. 2022 Sep 22;10(4):40. doi: 10.3390/jdb10040040. |
Biallelic mutations of TTC12 and TTC21B were identified in Chinese patients with multisystem ciliopathy syndromes
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Citation:
Hum Genomics. 2022 Oct 22;16(1):48. doi: 10.1186/s40246-022-00421-z Epub:
Not Epub Abstract:
Background: Abnormalities in cilia ultrastructure and function lead to a range of human phenotypes termed ciliopathies. Many... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen W, Wang F, Zeng W, Zhang X, Shen L, Zhang Y, Zhou X. Biallelic mutations of TTC12 and TTC21B were identified in Chinese patients with multisystem ciliopathy syndromes. Hum Genomics. 2022 Oct 22;16(1):48. doi: 10.1186/s40246-022-00421-z. |
Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia
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Citation:
Curr Biol. 2022 Oct 19:S0960-9822(22)01603-7. doi:10.1016/j.cub.2022.09.061. Online ahead of print Epub:
Yes Abstract:
Comb plates are large ciliary structures uniquely seen in comb jellies (ctenophores).1-3 A comb plate is constructed from tens... Citation Extract: Jokura K, Sato Y, Shiba K, Inaba K. Two distinct compartments of a ctenophore comb plate provide structural and functional integrity for the motility of giant multicilia. Curr Biol. 2022 Oct 19:S0960-9822(22)01603-7. doi:10.1016/j.cub.2022.09.061. Online ahead of print. |
Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
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Citation:
Molec Cell. 2022;82(20):3840-3855.e8. doi:10.1016/j.molcel.2022.09.036 Epub:
Not Epub Abstract:
The use of alternative promoters, splicing, and cleavage and polyadenylation (APA) generates mRNA isoforms that expand the... Delivery Method:
transfection Organism or Cell Type:
cell culture: HeLa Citation Extract: Malka Y, Alkan F, Ju S, Körner P-R, Pataskar A, Shulman E, Loayza-Puch F, Champagne J, Wenzel C, Faller WJ, Elkon R, Lee C, Agami R. Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential. Molec Cell. 2022;82(20):3840-3855.e8. doi:10.1016/j.molcel.2022.09.036. |
Patterning of phase-separated condensates by Dnd1 controls cell fate
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.20.512863 Epub:
Not Epub Abstract:
Germ granules, condensates of phase-separated RNA and protein, are essential for germline development, but how these molecules... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Westerich KJ, Tarbashevich K, Gupta A, Zhu M, Hull K, Daniel Romo, Gross-Thebing T, Raz E. Patterning of phase-separated condensates by Dnd1 controls cell fate. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.20.512863 . |
Alternative splicing of apoptosis genes promotes human T cell survival
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Citation:
eLife. 2022;11:e80953. doi:10.7554/eLife.80953 Epub:
Not Epub Abstract:
Alternative splicing occurs in the vast majority of human genes, giving rise to distinct mRNA and protein isoforms. We, and... Delivery Method:
electroporation Organism or Cell Type:
cell culture: Jurkat Citation Extract: Blake D, Radens CM, Ferretti MB, Gazzara MR, Lynch KW. Alternative splicing of apoptosis genes promotes human T cell survival. eLife. 2022;11:e80953. doi:10.7554/eLife.80953. |
Lmo7 recruits myosin II heavy chain to regulate actomyosin contractility and apical domain size in Xenopus ectoderm
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Citation:
Development. 2022 May 15;149(10):dev200236. doi: 10.1242/dev.200236. Epub 2022 May 16 Epub:
Not Epub Abstract:
Apical constriction, or a reduction in size of the apical domain, underlies many morphogenetic events during development.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Matsuda M, Chu CW, Sokol SY. Lmo7 recruits myosin II heavy chain to regulate actomyosin contractility and apical domain size in Xenopus ectoderm. Development. 2022 May 15;149(10):dev200236. doi: 10.1242/dev.200236. Epub 2022 May 16. |
Functional testing of BMP pathway variants identified on whole exome sequencing in a patient with delayed-onset fibrodysplasia ossificans progressiva (FOP) using ACVR1R206H -specific human cellular and zebrafish models
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Citation:
J Bone Miner Res. 2022 Sep 25. doi: 10.1002/jbmr.4711. Online ahead of print Epub:
Not Epub Abstract:
Bone morphogenetic protein (BMP) signaling is critical in skeletal development. Over-activation can trigger heterotopic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wentworth KL, Lalonde RL, Groppe JC, Brewer N, Moody T, Hansberry S, Taylor K, Shore EM, Kaplan FS, Pignolo RJ, Yelick PC, Hsiao EC. Functional testing of BMP pathway variants identified on whole exome sequencing in a patient with delayed-onset fibrodysplasia ossificans progressiva (FOP) using ACVR1R206H -specific human cellular and zebrafish models. J Bone Miner Res. 2022 Sep 25. doi: 10.1002/jbmr.4711. Online ahead of print. |
Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona
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Citation:
Development. 2022;149(21):dev200215. doi:10.1242/dev.200215 Epub:
Not Epub Abstract:
Ventral tail bending, which is transient but pronounced, is found in many chordate embryos and constitutes an interesting model... Delivery Method:
microinjection Organism or Cell Type:
Ciona robusta (ascidian) Citation Extract: Kogure YS, Muraoka H, Koizumi WC, Gelin-alessi R, Godard B, Oka K, Heisenberg C-P, Hotta K. Admp regulates tail bending by controlling ventral epidermal cell polarity via phosphorylated myosin localization in Ciona. Development. 2022;149(21):dev200215. doi:10.1242/dev.200215. |