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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton
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Citation:
Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409 Epub:
Not Epub Abstract:
The regulated expansion of chondrocytes within growth plates and joints ensures proper skeletal development through adulthood.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Smeeton J, Natarajan N, Naveen Kumar A, Miyashita T, Baddam P, Fabian P, Graf D, Crump JG. Zebrafish model for spondylo-megaepiphyseal-metaphyseal dysplasia reveals post-embryonic roles of Nkx3.2 in the skeleton. Development. 2021 Jan 25;148(2):dev193409. doi: 10.1242/dev.193409. |
Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos
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Citation:
Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012 Epub:
Not Epub Abstract:
The ascidian larval tail contains muscle cells for swimming. Most of these muscle cells differentiate autonomously. The genetic... Organism or Cell Type:
Ascidian Citation Extract: Yu D, Iwamura Y, Satou Y, Oda-Ishii I. Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos. Dev Biol. 2021;[Epub] doi:10.1016/j.ydbio.2021.12.012. |
Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011 Epub:
Not Epub Abstract:
Epithelial cell properties are determined by the polarized distribution of membrane lipids, the cytoskeleton, and adhesive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rosa JB, Nassman KY, Sagasti A. Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.23.474011. |
Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos
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Citation:
Cells. 2022;11(1):44. doi:10.3390/cells11010044 Epub:
Not Epub Abstract:
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE)... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yoon J, Kumar V, Goutam RS, Kim S-C, Park S, Lee U, Kim J. Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos. Cells. 2022;11(1):44. doi:10.3390/cells11010044. |
Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.21.473736 Epub:
Not Epub Abstract:
Aim: Tissue factor (TF), an initiator of the extrinsic coagulation pathway, is crucial for embryogenesis, as mice lacking TF... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.21.473736. |
Molecular mechanisms of embryonic tail development in the self-fertilizing mangrove killifish Kryptolebias marmoratus
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Citation:
Development. 2021 Dec 15;148(24):dev199675. doi: 10.1242/dev.199675. Epub 2021 Dec 24 Epub:
Not Epub Abstract:
Using the self-fertilizing mangrove killifish, we characterized two mutants, shorttail (stl) and balltail (btl). These mutants... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Saud HA, O'Neill PA, Ono Y, Verbruggen B, Van Aerle R, Kim J, Lee JS, Ring BC, Kudoh T. Molecular mechanisms of embryonic tail development in the self-fertilizing mangrove killifish Kryptolebias marmoratus. Development. 2021 Dec 15;148(24):dev199675. doi: 10.1242/dev.199675. Epub 2021 Dec 24. |
Methylmercury-induced hair cell loss requires hydrogen peroxide production and leukocytes in zebrafish embryos
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Citation:
Toxicol Lett. 2021 Dec 23:S0378-4274(21)00918-8. doi: 10.1016/j.toxlet.2021.12.012. Online ahead of print Epub:
Yes Abstract:
Hearing impairment and deafness is frequently observed as one of the neurological signs in patients with Minamata disease... Organism or Cell Type:
zebrafish Citation Extract: Luo Z, Guo S, Ho NY, Takamiya M, Strähle U, Yang L. Methylmercury-induced hair cell loss requires hydrogen peroxide production and leukocytes in zebrafish embryos. Toxicol Lett. 2021 Dec 23:S0378-4274(21)00918-8. doi: 10.1016/j.toxlet.2021.12.012. Online ahead of print. |
Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish
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Citation:
Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258 Epub:
Yes Abstract:
Cytochrome P45011A1, encoded by Cyp11a1, converts cholesterol to pregnenolone (P5), the first and rate-limiting step in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Ye D, Zhang F, Zhang R, Zhu J, Wang H, He M, Sun Y. Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 2021;[epub] doi:10.1210/endocr/bqab258. |
Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs
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Citation:
Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858 Epub:
Not Epub Abstract:
Marked epigenetic reprogramming is essential to convert terminally differentiated gametes to totipotent embryos. It remains... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu X, Zhang H, Zhang B, Zhang Y, Wang Q, Shen W, Wu X, Li L, Xia W, Nakamura R, Liu B, Liu F, Takeda H, Meng A, Xie W. Methylome inheritance and enhancer dememorization reset an epigenetic gate safeguarding embryonic programs. Sci Adv. 2021;7(52):eabl3858 doi:10.1126/sciadv.abl3858. |
Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis
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Citation:
Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025 Epub:
Not Epub Abstract:
How tissues acquire complex shapes is a fundamental question in biology and regenerative medicine. Zebrafish semicircular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Munjal A, Hannezo A, Tsai TY-C, Mitchison TJ, Megason SG. Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis. Cell. 2021;184(26):6313-25. doi:10.1016/j.cell.2021.11.025. |