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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
There are 12176 scientific papers returned from the database with the search filters currently being used below.
Left-right symmetry of zebrafish embryos requires somite surface tension
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Citation:
Nature. 2022;[Epub ahead of print] doi:10.1038/s41586-022-04646-9 Epub:
Yes Abstract:
The body axis of vertebrate embryos is periodically segmented into bilaterally symmetric pairs of somites2. The anteroposterior... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Naganathan SR, Popović M, Oates AC. Left-right symmetry of zebrafish embryos requires somite surface tension. Nature. 2022;[Epub ahead of print] doi:10.1038/s41586-022-04646-9. |
FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells
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Citation:
Blood Adv. 2023 Apr 11;7(7):1077-1091. doi: 10.1182/bloodadvances.2022007910. PMID: 36322817; PMCID: PMC10111352 Epub:
Not Epub Abstract:
Noncanonical exon usage plays many important roles in cellular phenotypes, but its contribution to human B-cell development... Delivery Method:
electroporation Organism or Cell Type:
cell culture: REH from B-Cell Acute Lymphoblastic Leukemia patients Citation Extract: Yang SY, Hayer KE, Fazelinia H, Spruce LA, Asnani M, Black KL, Naqvi AS, Pillai V, Barash Y, Elenitoba-Johnson KSJ, Thomas-Tikhonenko A. FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells. Blood Adv. 2023 Apr 11;7(7):1077-1091. doi: 10.1182/bloodadvances.2022007910. PMID: 36322817; PMCID: PMC10111352. |
Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health
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Citation:
Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748 Epub:
Not Epub Abstract:
Zebrafish larvae, especially gene-specific mutants and transgenic lines, are increasingly used to study vertebrate skeletal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Sojan JM, Raman R, Muller M, Carnevali O, Renn J. Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health. Int J Mol Sci. 2022; 23(9):4748. doi:10.3390/ijms23094748. |
Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish
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Citation:
Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110 Epub:
Not Epub Abstract:
Background: Colony-stimulating factor 3 (CSF3), more commonly known as granulocyte colony-stimulating factor (G-CSF), acts via... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Meier AB, Basheer F, Sertori R, Laird M, Liongue C, Ward AC. Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish. Front Biosci (Landmark Ed). 2022 Mar 28;27(4):110. doi: 10.31083/j.fbl2704110. |
Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells
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Citation:
Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print Epub:
Not Epub Abstract:
Cellular metabolism plays both an active and passive role in embryonic development, pluripotency, and cell-fate decisions.... Delivery Method:
cell culture: murine embryonic stem cells Citation Extract: Dierolf JG, Hunter HLM, Watson AJ, Betts DH. Modulation of PKM1/2 levels by steric blocking morpholinos alters the metabolic and pluripotent state of murine pluripotent stem cells. Stem Cells Dev. 2022 Apr 25. doi: 10.1089/scd.2021.0347. Online ahead of print. |
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
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Citation:
Cell Death Discov. 2023 Jul 5;9(1):226. doi: 10.1038/s41420-023-01507-w. PMID: 37407568; PMCID: PMC10323006 Epub:
Not Epub Abstract:
STAT3 and HIF1α are two fundamental transcription factors involved in many merging processes, like angiogenesis, metabolism,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Dinarello A, Betto RM, Diamante L, Tesoriere A, Ghirardo R, Cioccarelli C, Meneghetti G, Peron M, Laquatra C, Tiso N, Martello G, Argenton F. STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia. Cell Death Discov. 2023 Jul 5;9(1):226. doi: 10.1038/s41420-023-01507-w. PMID: 37407568; PMCID: PMC10323006. |
Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket
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Citation:
iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280 Epub:
Yes Abstract:
In the mammalian intestine, stem cells (ISCs) replicate in basal crypts, translocate along the villus, and undergo cell death.... Delivery Method:
Vivo-Morphoino intestinal gavage Organism or Cell Type:
zebrafish Citation Extract: Tavakoli S, Zhu S, Matsudaira P. Cell Clusters Containing Intestinal Stem Cells Line the Zebrafish Intestine Intervillus Pocket. iScience. 2022;104280 [Epub]. doi:10.1016/j.isci.2022.104280. |
VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway
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Citation:
Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3 Epub:
Not Epub Abstract:
The voltage-dependent anion channel 1 (VDAC1) was first described as a mitochondrial porin that mediates the flux of... Delivery Method:
subretinal injection Organism or Cell Type:
male and female Long Evans rats (Rattus norvegicus) Citation Extract: de Sousa E, Móvio MI, de Lima-Vasconcellos TH, Dos Santos GB, Dos Santos Gomes T, Walter LT, da Silva DA, Rodrigues T, Cerchiaro G, Kihara AH. VDAC1 regulates neuronal cell loss after retinal trauma injury by a mitochondria-independent pathway. Cell Death Dis. 2022 Apr 21;13(4):393. doi: 10.1038/s41419-022-04755-3. |
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio
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Citation:
Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119 Epub:
Not Epub Abstract:
Hypocretin (Hcrt), also known as orexin, neuropeptide signaling stabilizes sleep and wakefulness in all vertebrates. A lack of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holm A, Possovre M-L, Bandarabadi M, Moseholm KF, Justinussen JL, Bozic I, Lemcke R, Arribat Y, Amati F, Silahtaroglu A, Juventin M, Adamantidis A, Tafti M, Kornum BR. The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio. Proc Nat Acad Sci USA. 2022;117(17):e2112225119 [Epub] doi:10.1073/pnas.2112225119. |
Therapeutic Potential of CKD-504, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Zebrafish Model of Neuromuscular Junction Disorders
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Citation:
Mol Cells. 2022;45(4):231-42. doi:10.14348/molcells.2022.5005 Epub:
Not Epub Abstract:
The neuromuscular junction (NMJ), which is a synapse for signal transmission from motor neurons to muscle cells, has emerged as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jeong HS, Kim HJ, Kim D-H, Chung KW, Choi B-O, Lee JE. Therapeutic Potential of CKD-504, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Zebrafish Model of Neuromuscular Junction Disorders. Mol Cells. 2022;45(4):231-42. doi:10.14348/molcells.2022.5005. |