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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.07.05.451064 Epub:
Not Epub Abstract:
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis – a critical... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Saraswathy VM, Sharma P, Kurup AJ, Polès S, Poulain M, Fürthauer M. The E3 Ubiquitin Ligase Mindbomb1 controls zebrafish Planar Cell Polarity. bioRxiv. 2021;[preprint] doi:10.1101/2021.07.05.451064 . |
Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy
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Citation:
Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons that is caused by a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koh A, Sarusie MV, Ohmer J, Fischer U, Winkler C and Wohland T. Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy. Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904. |
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
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Citation:
Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6 Epub:
Not Epub Abstract:
The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed in endothelial cells (ECs), where it finely... Delivery Method:
Endo-Porter, microinjection Organism or Cell Type:
cell culture: HUVEC/TERT2, zebrafish Citation Extract: Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C. A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6. |
The miR-430 locus with extreme promoter density is a transcription body organizer, which facilitates long range regulation in zygotic genome activation
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455629 Epub:
Not Epub Abstract:
In anamniote embryos the major wave of zygotic genome activation (ZGA) starts during the mid-blastula transition. This major... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, Gustincich S, Sanges R, Burgess SM, Beggs AD, Mueller FD. The miR-430 locus with extreme promoter density is a transcription body organizer, which facilitates long range regulation in zygotic genome activation. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455629. |
Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
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Citation:
Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733 Epub:
Not Epub Abstract:
Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tessadori F, Tsingos E, Colizzi ES, Kruse F, van den Brink SC, van den Boogaard M, Christoffels VM, Merks RM, Bakkers J. Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733. |
Who is the best surrogate for germ stem cell transplantation in fish?
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455047 Epub:
Not Epub Abstract:
Surrogate reproduction technology in fish has potential for aquaculture as well as endangered species preservation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.09.455047. |
Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing
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Citation:
Development. 2021 Aug 10:dev.199771. doi: 10.1242/dev.199771. Online ahead of print Epub:
Yes Abstract:
The Krüppel-like factor (Klf) gene family encodes for transcription factors that play an important role in the regulation of... Organism or Cell Type:
Mnemiopsis leidyi (ctenophore) Citation Extract: Presnell JS, Browne WE. Krüppel-like factor gene function in the ctenophore Mnemiopsis leidyi assessed by CRISPR/Cas9-mediated genome editing. Development. 2021 Aug 10:dev.199771. doi: 10.1242/dev.199771. Online ahead of print. |
Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development
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Citation:
PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698 Epub:
Not Epub Abstract:
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo M-M, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E. Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development. PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698. |
Deep learning to design nuclear-targeting abiotic miniproteins
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Citation:
Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3 Epub:
Not Epub Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space... Delivery Method:
protein-linked Organism or Cell Type:
cell culture Citation Extract: Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep learning to design nuclear-targeting abiotic miniproteins. Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3. |
Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446 Epub:
Not Epub Abstract:
The deep-branching eukaryote Giardia lamblia is an extracellular parasite that attaches to the host intestine via a microtubule... Delivery Method:
electroporation Organism or Cell Type:
Giardia lamblia Citation Extract: Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446. |