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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype
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Citation:
Am J Hum Genet. 2021 Oct 1:S0002-9297(21)00343-8. doi: 10.1016/j.ajhg.2021.09.007. Online ahead of print Epub:
Not Epub Abstract:
Upregulated signal flow through RAS and the mitogen-associated protein kinase (MAPK) cascade is the unifying mechanistic theme... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Motta M, Fasano G, Gredy S, Brinkmann J, Bonnard AA, Simsek-Kiper PO, Gulec EY, Essaddam L, Utine GE, Guarnetti Prandi I, Venditti M, Pantaleoni F, Radio FC, Ciolfi A, Petrini S, Consoli F, Vignal C, Hepbasli D, Ullrich M, de Boer E, Vissers LELM, Gritli S, Rossi C, De Luca A, Ben Becher S, Gelb BD, Dallapiccola B, Lauri A, Chillemi G, Schuh K, Cavé H, Zenker M, Tartaglia M. SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype. Am J Hum Genet. 2021 Oct 1:S0002-9297(21)00343-8. doi: 10.1016/j.ajhg.2021.09.007. Online ahead of print. |
Crucial role of dead end gene for primordial germ cell survival in rice field eel (Monopterus albus)
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Citation:
Theriogenology. 2021 Oct 3;176:188-193. doi: 10.1016/j.theriogenology.2021.09.036. Online ahead of print Epub:
Not Epub Abstract:
The dead end gene has been identified as a essential factor for Primordial germ cells (PGCs) migration and survival in many... Delivery Method:
microinjection Organism or Cell Type:
Monopterus albus (rice field eel) Citation Extract: Hu Q, Xiao Q, Tian H, Li D, Li Z. Crucial role of dead end gene for primordial germ cell survival in rice field eel (Monopterus albus). Theriogenology. 2021 Oct 3;176:188-193. doi: 10.1016/j.theriogenology.2021.09.036. Online ahead of print. |
Otic Neurogenesis in Xenopus laevis: Proliferation, Differentiation, and the Role of Eya1
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Citation:
Front Neuroanat. 2021 Sep 20;15:722374. doi: 10.3389/fnana.2021.722374. eCollection 2021 Epub:
Not Epub Abstract:
Using immunostaining and confocal microscopy, we here provide the first detailed description of otic neurogenesis in Xenopus... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Almasoudi SH, Schlosser G. Otic Neurogenesis in Xenopus laevis: Proliferation, Differentiation, and the Role of Eya1. Front Neuroanat. 2021 Sep 20;15:722374. doi: 10.3389/fnana.2021.722374. eCollection 2021. |
Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle
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Citation:
Int J Mol Sci. 2021;22(19):10831. doi:10.3390/ijms221910831 Epub:
Not Epub Abstract:
Circadian phase shifts in peripheral clocks induced by changes in feeding rhythm often result in insulin resistance. However,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Shiuchi T, Otsuka A, Shimizu N, Chikahisa S, Séi H. Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle. Int J Mol Sci. 2021;22(19):10831. doi:10.3390/ijms221910831. |
The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos
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Citation:
Commun Biol. 2021;4:1158. doi:10.1038/s42003-021-02688-9 Epub:
Not Epub Abstract:
The enpp ectonucleotidases regulate lipidic and purinergic signalling pathways by controlling the extracellular concentrations... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Massé K, Bhamra S, Paroissin C, Maneta-Peyret L, Boué-Grabot E, Jones EA. The enpp4 ectonucleotidase regulates kidney patterning signalling networks in Xenopus embryos. Commun Biol. 2021;4:1158. doi:10.1038/s42003-021-02688-9. |
Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers
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Citation:
JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327 Epub:
Not Epub Abstract:
Therapeutic macromolecules such as proteins and oligonucleotides can be highly efficacious but are often limited to... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa, mice Citation Extract: López-Vidal EM, Schissel CK, Mohapatra S, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers. JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327. |
Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish
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Citation:
Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782 Epub:
Not Epub Abstract:
In the zebrafish embryo, the onset of blood flow generates fluid shear stress on endocardial cells, which are specialized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paolini A, Fontana F, Pham VC, Rödel CJ, Abdelilah-Seyfried S. Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish. Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782. |
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
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Citation:
eLife. 2021;10:e66588 doi:10.7554/eLife.66588 Epub:
Not Epub Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know... Delivery Method:
electroporation Organism or Cell Type:
Coturnix japonica (quail) Citation Extract: Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B. Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny. eLife. 2021;10:e66588 doi:10.7554/eLife.66588. |
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
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Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022 Epub:
Not Epub Abstract:
Actin-rich cellular protrusions direct versatile biological processes from cancer cell invasion to dendritic spine development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J. SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022. |
The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration
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Citation:
Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940 Epub:
Not Epub Abstract:
Warm-blooded vertebrates regenerate lost limbs and their parts in general much worse than fishes and amphibians. We previously... Delivery Method:
microinjection, Vivo-Morpholino Organism or Cell Type:
Xenopus laevis Citation Extract: Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG. The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940. |