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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling
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Citation:
Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print Epub:
Not Epub Abstract:
Background: Retinol binding protein 1 (Rbp1) acts as an intracellular regulator of vitamin A metabolism and retinoid transport... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Flach H, Basten T, Schreiner C, Dietmann P, Greco S, Nies L, Roßmanith N, Walter S, Kühl M, Kühl SJ. Retinol Binding Protein 1 Affects Xenopus Anterior Neural Development via All-trans Retinoic Acid Signalling. Dev Dyn. 2021 Feb 11. doi: 10.1002/dvdy.313. Online ahead of print. |
sGC activity and regulation of blood flow in a Zebrafish model system
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Citation:
Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171 Epub:
Yes Abstract:
Soluble guanylyl cyclase (sGC) protein is a heterodimer formed by two subunits encoded by the GUCY1A1 and GUCY1B1 genes. The... Organism or Cell Type:
zebrafish Citation Extract: Vishnolia KK, Rakovic A, Hoene C, Tarhbalouti K, Aherrahrou Z, Erdmann J. sGC activity and regulation of blood flow in a Zebrafish model system. Front Physiol. 2021;[provisional] doi: 10.3389/fphys.2021.633171. |
Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.02.10.430654 Epub:
Not Epub Abstract:
Wall shear stress (WSS) in micro-vasculature contributes to biomechanical cues to regulate mechanotransduction underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Roustaei M, Baek KI, Wang Z, Cavallero S, Satta S, Lai A, O'Donnell R, Vedula V, Ding Y, Marsden AL, Hsiai T. Computational Simulation of 4-D Micro-Circular Network in Zebrafish Tail Amputation and Regeneration. bioRxiv. 2021;[preprint] doi:10.1101/2021.02.10.430654 . |
Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning
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Citation:
Nat Methods. 2021. doi:10.1038/s41592-021-01058-x Epub:
Not Epub Abstract:
Light-field microscopy has emerged as a technique of choice for high-speed volumetric imaging of fast biological processes.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Z, Zhu L, Zhang H, Li G, Yi C, Li Y, Yang Y, Ding Y, Zhen M, Gao S, Hsiai TK, Fei P. Real-time volumetric reconstruction of biological dynamics with light-field microscopy and deep learning. Nat Methods. 2021. doi:10.1038/s41592-021-01058-x. |
Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish
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Citation:
Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409 Epub:
Not Epub Abstract:
Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid... Delivery Method:
injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Sengupta A, Padhan DK, Ganguly A, Sen M. Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish. Front Cell Devel Biol. 2021;9:34. doi:10.3389/fcell.2021.627409. |
Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation
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Citation:
Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w Epub:
Not Epub Abstract:
Neurofibromatosis Type 1 (NF1) is a genetic condition affecting approximately 1:3500 persons worldwide. The NF1 gene codes for... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: PC12 Citation Extract: Biayna J, Mazuelas H, Gel B, Terribas E, Dumbovic G, Rosas I, Fernández-Rodriguez J, Blanco I, Castellanos E, Carrió M, Lazaro C, Serra E. Using antisense oligonucleotides for the physiological modulation of the alternative splicing of NF1 exon 23a during PC12 neuronal differentiation. Sci Rep. 2021;11(1):3661. doi:10.1038/s41598-021-83152-w. |
Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides
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Citation:
Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disease caused by frameshift or nonsense mutations in the DMD gene... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture:CXMDJ immortalized myoblasts Citation Extract: Tone Y, Mamchaoui K, Tsoumpra MK, Hashimoto Y, Terada R, Maruyama R, Gait MJ, Arzumanov AA, McClorey G, Imamura M, Takeda S, Yokota T, Wood MJA, Mouly V, Aoki Y. Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides. Nucleic Acid Ther. 2021 Feb 9. doi: 10.1089/nat.2020.0907. Online ahead of print. |
Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation
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Citation:
Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693 Epub:
Not Epub Abstract:
Integrated molecular signals regulate cell fate decisions in the embryonic aortic endothelium to drive hematopoietic stem cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maglitto A, Mariani SA, de Pater E, Rodriguez-Seoane C, Vink CS, Piao X, Lukke M-L, Dzierzak E. Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation. Blood Adv. 2021;5(3):829–842. doi:10.1182/bloodadvances.2020003693. |
Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386 Epub:
Not Epub Abstract:
The atrioventricular canal (AVC) is an essential feature of the heart, which separates the atrium from the ventricle. During... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Abu NK, Migdał M, Quinn TA, Poon K-L, Łapinski M, Sulej A, Pawlak M, Bugajski Ł, Piwocka K, Brand T, Kohl P, Korzh V, Winata C. Transcriptome profile of the zebrafish atrioventricular canal reveals molecular signatures of pacemaker and valve mesenchyme. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.27.428386. |
Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405 Epub:
Not Epub Abstract:
Convergent extension is an evolutionarily conserved collective cell movement that elongates the body axis of all animals and is... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Weng S, Huebner RJ, Wallingford JB. Convergent extension requires adhesion-dependent biomechanical integration of cell crawling and junction contraction. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.12.426405 . |