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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
There are 12152 scientific papers returned from the database with the search filters currently being used below.
DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells
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Citation:
Elife. 2022 May 30;11:e72302. doi: 10.7554/eLife.72302. PMID: 35635436; PMCID: PMC9197390 Epub:
Not Epub Abstract:
In a previous study, it was reported that Yap1 and Wwtr1 in zebrafish regulates the morphogenesis of the posterior body and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lai JKH, Toh PJY, Cognart HA, Chouhan G, Saunders TE. DNA-damage induced cell death in yap1;wwtr1 mutant epidermal basal cells. Elife. 2022 May 30;11:e72302. doi: 10.7554/eLife.72302. PMID: 35635436; PMCID: PMC9197390. |
Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy
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Citation:
Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904 Epub:
Not Epub Abstract:
Spinal Muscular Atrophy (SMA) is a progressive neurodegenerative disease affecting lower motor neurons that is caused by a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Koh A, Sarusie MV, Ohmer J, Fischer U, Winkler C and Wohland T. Fluorescence Correlation Spectroscopy Reveals Survival Motor Neuron Oligomerization but No Active Transport in Motor Axons of a Zebrafish Model for Spinal Muscular Atrophy. Front Cell Dev Biol. 2021;9:639904. doi:10.3389/fcell.2021.639904. |
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
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Citation:
Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6 Epub:
Not Epub Abstract:
The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed in endothelial cells (ECs), where it finely... Delivery Method:
Endo-Porter, microinjection Organism or Cell Type:
cell culture: HUVEC/TERT2, zebrafish Citation Extract: Pradella D, Deflorian G, Pezzotta A, Di Matteo A, Belloni E, Campolungo D, Paradisi A, Bugatti M, Vermi W, Campioni M, Chiapparino A, Scietti L, Forneris F, Giampietro C, Volf N, Rehman M, Zacchigna S, Paronetto MP, Pistocchi A, Eichmann A, Mehlen P, Ghigna C. A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis. Nat Comm. 2021;12(1):4872. doi:10.1038/s41467-021-24998-6. |
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation
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Citation:
Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021 Epub:
Not Epub Abstract:
In anamniote embryos, the major wave of zygotic genome activation starts during the mid-blastula transition. However, some... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, Finaurini S, Gustincich S, Sanges R, Burgess S, Beggs A, Müller F. The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation. Dev Cell. 2023 Jan 23;58(2):155-170.e8. doi: 10.1016/j.devcel.2022.12.007. PMID: 36693321; PMCID: PMC9904021. |
Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process
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Citation:
Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733 Epub:
Not Epub Abstract:
Organ laterality refers to the left-right asymmetry in disposition and conformation of internal organs and is established... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tessadori F, Tsingos E, Colizzi ES, Kruse F, van den Brink SC, van den Boogaard M, Christoffels VM, Merks RM, Bakkers J. Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process. Elife. 2021 Aug 10;10:e61733. doi: 10.7554/eLife.61733. |
Who is the best surrogate for germ stem cell transplantation in fish?
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Citation:
Aquaculture, Volume 549, 2022, 737759, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2021.737759 Epub:
Not Epub Abstract:
Surrogate broodstock technology in fishes has potential for aquaculture as well as endangered species conservation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. Aquaculture, Volume 549, 2022, 737759, ISSN 0044-8486, https://doi.org/10.1016/j.aquaculture.2021.737759. |
Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development
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Citation:
PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698 Epub:
Not Epub Abstract:
Hirschsprung disease (HSCR) is a complex genetic disease characterized by absence of ganglia in the intestine. HSCR etiology... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuil LE, MacKenzie KC, Tang CS, Windster JD, Le TL, Karim A, de Graaf BM, van der Helm R, van Bever Y, Sloots CEJ, Meeussen C, Tibboel D, de Klein A, Wijnen RMH, Amiel J, Lyonnet S, Garcia-Barcelo M-M, Tam PKH, Alves MM, Brooks AS, Hofstra RMW, Brosens E. Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development. PLoS Genet. 2021;17(8):e1009698. doi:10.1371/journal.pgen.1009698. |
Deep learning to design nuclear-targeting abiotic miniproteins
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Citation:
Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3 Epub:
Not Epub Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space... Delivery Method:
protein-linked Organism or Cell Type:
cell culture Citation Extract: Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep learning to design nuclear-targeting abiotic miniproteins. Nat Chem. 2021;[Epub ahead of print] doi:10.1038/s41557-021-00766-3. |
Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury
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Citation:
Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print Epub:
Yes Abstract:
In strong contrast to limited repair within the mammalian central nervous system, the spinal cord of adult zebrafish is capable... Organism or Cell Type:
zebrafish Citation Extract: Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ. Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury. Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print. |
Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish
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Citation:
PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693 Epub:
Not Epub Abstract:
The ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gao S, Wang Z, Wang L, Wang H, Yuan H, Liu X, Chen S, Chen Z, de Thé H, Zhang W, Zhang Y, Zhu J, Zhou J. Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish. PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693. |