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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Hallmarks of primary neurulation are conserved in the zebrafish forebrain

Authors:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster RM
Citation:
Commun Biol. 2021 Jan 29;4(1):147. doi: 10.1038/s42003-021-01655-8
Epub:
Not Epub
Abstract:
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster RM. Hallmarks of primary neurulation are conserved in the zebrafish forebrain. Commun Biol. 2021 Jan 29;4(1):147. doi: 10.1038/s42003-021-01655-8.

Protein 14-3-3 eta (YWHAH) is essential for normal meiotic spindle assembly during in vitro maturation of mouse oocytes

Authors:
De S, Davis S, Letwin D, Mozena C, Kline D
Citation:
Am Soc Cell Bio Conference. 2012;Poster 1967
Epub:
Not Epub
Abstract:
The 14-3-3 (YWHA) proteins are known to be central mediators in various cellular signaling pathways regulating...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
De S, Davis S, Letwin D, Mozena C, Kline D. Protein 14-3-3 eta (YWHAH) is essential for normal meiotic spindle assembly during in vitro maturation of mouse oocytes. Am Soc Cell Bio Conference. 2012;Poster 1967.

Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function

Authors:
Nommick A, Boutin C, Rosnet O, Bazellieres E, Thome V, Loiseau E, Viallat A, Kodjabachian L
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.30.428946
Epub:
Not Epub
Abstract:
Ciliated epithelia perform a variety of essential functions across animal evolution, ranging from locomotion of marine...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nommick A, Boutin C, Rosnet O, Bazellieres E, Thome V, Loiseau E, Viallat A, Kodjabachian L. Lrrcc1 and Ccdc61 are conserved effectors of multiciliated cell function. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.30.428946.

Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m6A methylation level to cause lipid metabolism disorder in zebrafish

Authors:
Sun L, Gao M, Qian Q, Guo Z, Zhu P, Wang X, Wang H
Citation:
Sci Total Environ. 2021 Jan 22;770:145285. doi: 10.1016/j.scitotenv.2021.145285. Online ahead of print
Epub:
Not Epub
Abstract:
Chronic exposure of triclosan (TCS) to zebrafish triggers high incidence of fatty liver and hepatitis; however, the underlying...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun L, Gao M, Qian Q, Guo Z, Zhu P, Wang X, Wang H. Triclosan-induced abnormal expression of miR-30b regulates fto-mediated m6A methylation level to cause lipid metabolism disorder in zebrafish. Sci Total Environ. 2021 Jan 22;770:145285. doi: 10.1016/j.scitotenv.2021.145285. Online ahead of print.

Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome

Authors:
Lu JY, Chang L, Li T, Wang T, Yin Y, Zhan G, Han X, Zhang K, Tao Y, Percharde M, Wang L, Peng Q, Yan P, Zhang H, Bi X, Shao W, Hong Y, Wu Z, Ma R, Wang P, Li We, Zhang J, Chang Z, Hou Y, Zhu B, Ramalho-Santos M, Li P, Xie W, Na J, Sun Y, Shen X
Citation:
Cell Res. 2021. doi:10.1038/s41422-020-00466-6
Epub:
Not Epub
Abstract:
Organization of the genome into euchromatin and heterochromatin appears to be evolutionarily conserved and relatively stable...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Lu JY, Chang L, Li T, Wang T, Yin Y, Zhan G, Han X, Zhang K, Tao Y, Percharde M, Wang L, Peng Q, Yan P, Zhang H, Bi X, Shao W, Hong Y, Wu Z, Ma R, Wang P, Li We, Zhang J, Chang Z, Hou Y, Zhu B, Ramalho-Santos M, Li P, Xie W, Na J, Sun Y, Shen X. Homotypic clustering of L1 and B1/Alu repeats compartmentalizes the 3D genome. Cell Res. 2021. doi:10.1038/s41422-020-00466-6.

A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa

Authors:
Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda K-H, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T
Citation:
Commun Biol. 2021;4:140. doi:10.1038/s42003-021-01662-9
Epub:
Not Epub
Abstract:
The genetic basis of Japanese autosomal recessive retinitis pigmentosa (ARRP) remains largely unknown. Herein, we applied a 2-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishiguchi KM, Miya F, Mori Y, Fujita K, Akiyama M, Kamatani T, Koyanagi Y, Sato K, Takigawa T, Ueno S, Tsugita M, Kunikata H, Cisarova K, Nishino J, Murakami A, Abe T, Momozawa Y, Terasaki H, Wada Y, Sonoda K-H, Rivolta C, Tsunoda T, Tsujikawa M, Ikeda Y, Nakazawa T. A hypomorphic variant in EYS detected by genome-wide association study contributes toward retinitis pigmentosa. Commun Biol. 2021;4:140. doi:10.1038/s42003-021-01662-9.

ELOVL5 Participates in Embryonic Lipid Determination of Cellular Membranes and Cytoplasmic Droplets

Authors:
Lanzarini F, Pereira FA, de Camargo J, Oliveira AM, Belaz KRA, Melendez-Perez JJ, Eberlin MN, Brum MCS, Mesquita FS, Sudano MJ
Citation:
Int J Mol Sci. 2021;22(3):1311. doi:10.3390/ijms22031311
Epub:
Not Epub
Abstract:
Embryonic lipids are crucial for the formation of cellular membranes and dynamically participate in metabolic pathways. Cells...
Delivery Method:
Endo-Porter
Organism or Cell Type:
Bos taurus (cattle) embryo
Citation Extract:
Lanzarini F, Pereira FA, de Camargo J, Oliveira AM, Belaz KRA, Melendez-Perez JJ, Eberlin MN, Brum MCS, Mesquita FS, Sudano MJ. ELOVL5 Participates in Embryonic Lipid Determination of Cellular Membranes and Cytoplasmic Droplets. Int J Mol Sci. 2021;22(3):1311. doi:10.3390/ijms22031311 .

TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish

Authors:
Campanari ML, Marian A, Ciura S, Kabashi E
Citation:
Cells. 2021 Jan 22;10(2):221. doi: 10.3390/cells10020221
Epub:
Not Epub
Abstract:
The "distal axonopathy" hypothesis in amyotrophic lateral sclerosis (ALS) proposes that pathological changes occur at...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Campanari ML, Marian A, Ciura S, Kabashi E. TDP-43 Regulation of AChE Expression Can Mediate ALS-Like Phenotype in Zebrafish. Cells. 2021 Jan 22;10(2):221. doi: 10.3390/cells10020221.

The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning

Authors:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ
Citation:
Genes. 2021;12(2):170. https://doi.org/10.3390/genes12020170
Epub:
Not Epub
Abstract:
Precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm establishes the left–right...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ. The Axenfeld–Rieger Syndrome Gene FOXC1 Contributes to Left–Right Patterning. Genes. 2021;12(2):170. https://doi.org/10.3390/genes12020170 .

CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants

Authors:
Zarate YA, Uehara T, Abe K, Oginuma M, Harako S, Ishitani S, Lehesjoki A-E, Bierhals T, Kloth K, Ehmke N, Horn D, Holtgrewe M, Anderson K, Viskochil D, Edgar-Zarate CL, Sacoto MJG, Schnur RE, Morrow MM, Sanchez-Valle A, Pappas J, Rabin R, Muona M, Anttonen A-K, Platzer K, Luppe J, Gburek-Augustat J, Kaname T, Okamoto N, Mizuno S, Kaido Yusaku, Ohkuma Y, Hirose Y, Ishitani T, Kosaki K
Citation:
Genet Med. 2021;[Epub ahead of print] doi:10.1038/s41436-020-01091-9
Epub:
Yes
Abstract:
Purpose: To expand the recent description of a new neurodevelopmental syndrome related to alterations in CDK19. Methods:...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zarate YA, Uehara T, Abe K, Oginuma M, Harako S, Ishitani S, Lehesjoki A-E, Bierhals T, Kloth K, Ehmke N, Horn D, Holtgrewe M, Anderson K, Viskochil D, Edgar-Zarate CL, Sacoto MJG, Schnur RE, Morrow MM, Sanchez-Valle A, Pappas J, Rabin R, Muona M, Anttonen A-K, Platzer K, Luppe J, Gburek-Augustat J, Kaname T, Okamoto N, Mizuno S, Kaido Yusaku, Ohkuma Y, Hirose Y, Ishitani T, Kosaki K. CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants. Genet Med. 2021;[Epub ahead of print] doi:10.1038/s41436-020-01091-9.

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