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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep
Citation:
Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021 Epub:
Not Epub Abstract:
As a major protein of the polyhedral coat of coated pits and vesicles, clathrin molecules have been shown to play a... Delivery Method:
microinjection Organism or Cell Type:
Ovis aries (sheep oocytes) Citation Extract: Han Z, Hao X, Zhou CJ, Wang J, Wen X, Wang XY, Zhang DJ, Liang CG. Clathrin Heavy Chain 1 Plays Essential Roles During Oocyte Meiotic Spindle Formation and Early Embryonic Development in Sheep. Front Cell Dev Biol. 2021 Feb 25;9:609311. doi:10.3389/fcell.2021.609311. eCollection 2021. |
kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434917 Epub:
Not Epub Abstract:
Anterograde melanosome transport is essential for adaptive skin tanning response. However, the molecular components involved,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Subramaniam Y, Murthy D, Raja DA, Ramkumar A, Sivasubbu S, McEwan DG, Gokhale RS, Natarajan VT. kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434917. |
Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434829 Epub:
Not Epub Abstract:
Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xiao Y, Hoodless LJ, Petrucco L, Portugues R, Czopka T. Oligodendrocyte Precursor Cells Sculpt the Visual System by Regulating Axonal Remodeling. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.11.434829. |
miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury
Citation:
Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print Epub:
Not Epub Abstract:
This study aims to examine whether miR-31 promotes endogenous NSC proliferation and be used for spinal cord injury management.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li X, Gao Y, Tian F, Du R, Yuan Y, Li P, Liu F, Wang C. miR-31 promotes neural stem cell proliferation and restores motor function after spinal cord injury. Exp Biol Med (Maywood). 2021 Mar 9:1535370221997071. doi: 10.1177/1535370221997071. Online ahead of print. |
Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury
Citation:
bioRxiv. 2021;[preprint] doi:/10.1101/2021.03.11.435053 Epub:
Not Epub Abstract:
Unlike mammals, zebrafish can regenerate a damaged retina. Key to this regenerative response are Müller glia (MG) that divide... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Goldman D, Sahu A, Devi S, Jui J. Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury. bioRxiv. 2021;[preprint] doi:/10.1101/2021.03.11.435053. |
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome
Citation:
Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4 Epub:
Yes Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare, invariably fatal childhood premature aging disorder caused by a pre-... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Puttaraju M, Jackson M, Klein S, Shilo A, Bennett CF, Gordon L, Rigo F, Misteli T. Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome. Nat Med. 2021;[Epub ahead of print] doi:10.1038/s41591-021-01262-4. |
A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome
Citation:
Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11. Epub:
Not Epub Abstract:
Hutchinson–Gilford progeria syndrome (HGPS) is a rare accelerated aging disorder characterized by premature death from... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: human progeric fibroblasts, mice Citation Extract: Erdos MR, Cabral WA, Tavarez UL, Cao K, Gvozdenovic-Jeremic J, Narisu N, Zerfas PM, Crumley S, Boku Y, Hanson G, Mourich DV, Kole R, Eckhaus MA, Gordon LB, Collins FS. A targeted antisense therapeutic approach for Hutchinson–Gilford progeria syndrome. Nat Med. 2021 Mar;27(3):536-545. doi: 10.1038/s41591-021-01274-0. Epub 2021 Mar 11.. |
Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.03.10.434727 Epub:
Not Epub Abstract:
During early vertebrate heart development, the heart transitions from a linear tube to a complex asymmetric structure. This... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Derrick CJ, Pollitt EJG, Uruchurtu ASS, Hussein F, Noel ES. Lamb1a regulates atrial growth by limiting excessive, contractility-dependent second heart field addition during zebrafish heart development. bioRxiv. 2021;[preprint] doi:10.1101/2021.03.10.434727 . |
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients
Citation:
EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328 Epub:
Not Epub Abstract:
DMD is a rare disorder characterized by progressive muscle degeneration and premature death. Therapy development is delayed by... Delivery Method:
i.v. injection Organism or Cell Type:
mice mdx Citation Extract: Signorelli M, Ebrahimpoor M, Veth O, Hettne K, Verwey N, García‐Rodríguez R, Tanganyika‐deWinter CL, Lopez Hernandez LB, Cedillo RE, Díaz BG, Magnusson OT, Mei H, Tsonaka R, Aartsma‐Rus A, Spitali P. Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients. EMBO Mol Med. 2021;e13328. doi:10.15252/emmm.202013328. |
Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families
Citation:
Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061 Epub:
Not Epub Abstract:
Isolated Microspherophakia (MSP) is an autosomal recessive disorder characterised by a smaller than normal spherical lens. Till... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Madhangi M, Dutta D, Show S, Bhat VK, Rather MI, Tiwari A, Singh N, Duvvari MR, Murthy GJ, Kumar A, Nongthomba U. Exome sequencing and functional studies in zebrafish identify WDR8 as the causative gene for isolated Microspherophakia in Indian families. Hum Mol Genet. 2021;ddab061. doi:10.1093/hmg/ddab061. |