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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins
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Citation:
Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081 Epub:
Not Epub Abstract:
Previously, we isolated jacalin-related lectins termed PPL2, PPL3 (PPL3A, 3B and 3C) and PPL4 from the mantle secretory fluid... Delivery Method:
Endo-Porter Organism or Cell Type:
Pteria penguin (oyster) Citation Extract: Ogawa T, Sato R, Naganuma T, Liu K, Sato S, Sakaue S, Osada M, Yoshimi K, Muramoto K. Diversified Biomineralization Roles of Pteria penguin Pearl Shell Lectins as Matrix Proteins. Int J Mol Sci. 2021;22(3),1081. doi:10.3390/ijms22031081. |
A recurrent missense variant in EYA3 gene is associated with oculo-auriculo-vertebral spectrum
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Citation:
Hum Genet. 2021;[Epub ahead of print] doi:s00439-021-02255-6 Epub:
Yes Abstract:
Goldenhar syndrome or oculo-auriculo-vertebral spectrum (OAVS) is a complex developmental disorder characterized by asymmetric... Organism or Cell Type:
zebrafish Citation Extract: Tingaud-Sequeira A, Trimouille A, Salaria M, Stapleton R, Claverol S, Plaisant C, Bonneu M, Lopez E, Arveiler B, Lacombe D, Rooryck C. A recurrent missense variant in EYA3 gene is associated with oculo-auriculo-vertebral spectrum. Hum Genet. 2021;[Epub ahead of print] doi:s00439-021-02255-6. |
LIM Homeobox 4 (lhx4) regulates retinal neural differentiation and visual function in zebrafish
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Citation:
Sci Rep. 2021;11:1977. doi:10.1038/s41598-021-81211-w Epub:
Not Epub Abstract:
LIM homeobox 4 (LHX4) is expressed in the photoreceptors (PRs) of the outer nuclear layer (ONL) and bipolar cells (BCs) of the... Delivery Method:
microinjection, Vivo-Morpholino (ocular injection) Organism or Cell Type:
zebrafish Citation Extract: Guo R, Ge K, Wang Y, Lu M, Li F, Tian L, Gan L, Sheng D. LIM Homeobox 4 (lhx4) regulates retinal neural differentiation and visual function in zebrafish. Sci Rep. 2021;11:1977. doi:10.1038/s41598-021-81211-w. |
Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia
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Citation:
Biomedicines. 2021;9(2):100. doi:10.3390/biomedicines9020100 Epub:
Not Epub Abstract:
Congenital eye defects represent a large class of disorders affecting roughly 21 million children worldwide. Microphthalmia and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brastrom LK, Scott CA, Wang K, Slusarski DC. Functional Role of the RNA-Binding Protein Rbm24a and Its Target sox2 in Microphthalmia. Biomedicines. 2021;9(2):100. doi:10.3390/biomedicines9020100. |
Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/483362 Epub:
Not Epub Abstract:
Shwachman-Diamond syndrome (SDS; OMIM: #260400) is caused by variants in SBDS (Shwachman-Bodian-Diamond syndrome gene), which... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee S, Shin CH, Lee J, Jeong SD, Hong CY, Kim J-D, Kim A-R, Son SJ, Kokhan O, Yoo T, Ko JS, Sohn YB, Kim O-H, Ko JM, Cho T-J, Wright NT, Seong JK, Jin S-W, Kang HJ, Kim HH, Choi M. Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome. bioRxiv. 2021;[preprint] doi:10.1101/483362. |
Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos
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Citation:
J Vis Exp. 2020;(159):e61275. doi:10.3791/61275 Epub:
Not Epub Abstract:
Antimicrobial resistance, a major consequence of diagnostic uncertainty and antimicrobial overprescription, is an increasingly... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cafora M, Forti F, Briani F, Ghisotti D, Pistocchi A. Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos. J Vis Exp. 2020;(159):e61275. doi:10.3791/61275 . |
An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy
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Citation:
Brain. 2021;[Epub ahead of print] doi:10.1093/brain/awaa420 Epub:
Yes Abstract:
The extracellular matrix comprises a network of macromolecules such as collagens, proteoglycans and glycoproteins. VWA1 (von... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pagnamenta AT, Kaiyrzhanov R, Zou Y, Da'as SI, Maroofian R, Donkervoort S, Dominik N, Lauffer M, Ferla MP, Orioli A, Giess A, Tucci A, Beetz C, Sedghi M, Ansari B, Barresi R, Basiri K, Cortese A, Elgar G, Fernandez-Garcia MA, Yip J, Foley AR, Gutowski N, Jungbluth H, Lassche S, Lavin T, Marcelis C, Marks P, Marini-Bettolo C, Medne L, Moslemi A-R, Sarkozy A, Reilly MM, Muntoni F, Millan F, Muraresku CC, Need AC, Nemeth AH, Neuhaus SB, Norwood F, O'Donnell M, O’Driscoll M, Rankin J, Yum SW, Zolkipli-Cunningham Z, Brusius I, Wunderlich G, Genomics England Research Consortium, Karakaya M, Wirth B, Fakhro KA, Tajsharghi H, Bönnemann CG, Taylor JC, Houlden H. An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy. Brain. 2021;[Epub ahead of print] doi:10.1093/brain/awaa420. |
A regulatory sub-circuit downstream of Wnt signaling controls developmental transitions in neural crest formation
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Citation:
PLoS Genet. 2021;17(1):e1009296. doi:10.1371/journal.pgen.1009296 Epub:
Not Epub Abstract:
The process of cell fate commitment involves sequential changes in the gene expression profiles of embryonic progenitors. This... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Azambuja AP, Simoes-Costa M. A regulatory sub-circuit downstream of Wnt signaling controls developmental transitions in neural crest formation. PLoS Genet. 2021;17(1):e1009296. doi:10.1371/journal.pgen.1009296. |
Systemic antisense therapeutics inhibiting DUX4 expression improves muscle function in an FSHD mouse model
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Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.01.14.426659 Epub:
Not Epub Abstract:
Aberrant expression of the double homeobox 4 (DUX4) gene in skeletal muscle causes muscle deterioration and weakness in... Delivery Method:
Endo-Porter, Vivo-Morpholino Organism or Cell Type:
cell culture, mice Citation Extract: Lu-Nguyen N, Malerba A, Dickson G, Popplewell L. Systemic antisense therapeutics inhibiting DUX4 expression improves muscle function in an FSHD mouse model. bioRxiv. 2021;[preprint] doi:10.1101/2021.01.14.426659. |
The Resistance to Host Antimicrobial Peptides in Infections Caused by Daptomycin-Resistant Staphylococcus aureus
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Citation:
Antibiotics. 2021;10(2):96. doi:10.3390/antibiotics10020096 Epub:
Not Epub Abstract:
Daptomycin is an important antibiotic for the treatment of infections caused by Staphylococcus aureus. The emergence of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhuiyan MS, Jiang J-H, Kostoulias X, Theegala R, Lieschke GJ, Peleg AY. The Resistance to Host Antimicrobial Peptides in Infections Caused by Daptomycin-Resistant Staphylococcus aureus. Antibiotics. 2021;10(2):96. doi:10.3390/antibiotics10020096. |