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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Asymmetric Hapln1a drives regionalized cardiac ECM expansion and promotes heart morphogenesis in zebrafish development
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Citation:
Cardiovasc Res. 2021;cvab004. doi:10.1093/cvr/cvab004 Epub:
Not Epub Abstract:
Aims: Vertebrate heart development requires the complex morphogenesis of a linear tube to form the mature organ, a process... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Derrick CJ, Sánchez-Posada J, Hussein F, Tessadori F, Pollitt EJG, Savage AM, Wilkinson RN, Chico TJ, van Eeden FJ, Bakkers J, Noël ES. Asymmetric Hapln1a drives regionalized cardiac ECM expansion and promotes heart morphogenesis in zebrafish development. Cardiovasc Res. 2021;cvab004. doi:10.1093/cvr/cvab004. |
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy
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Citation:
J Cell Sci. 2021;134:jcs256255 doi:10.1242/jcs.256255 Epub:
Not Epub Abstract:
Mitophagy, the selective recycling of mitochondria through autophagy, is a crucial metabolic process induced by cellular stress... Organism or Cell Type:
zebrafish Citation Extract: Wrighton PJ, Shwartz A, Heo J-M, Quenzer ED, LaBella KA, Harper JW, Goessling W. Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy. J Cell Sci. 2021;134:jcs256255 doi:10.1242/jcs.256255. |
EPHA2 Segregates with Microphthalmia and Congenital Cataracts in Two Unrelated Families
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Citation:
Int J Mol Sci. 2021;22(4):2190. doi:10.3390/ijms22042190 Epub:
Not Epub Abstract:
EPHA2 is a transmembrane tyrosine kinase receptor that, when disrupted, causes congenital and age-related cataracts. Cat-Map... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Harding P, Toms M, Schiff E, Owen N, Bell S, Lloyd IC, Moosajee M. EPHA2 Segregates with Microphthalmia and Congenital Cataracts in Two Unrelated Families. Int J Mol Sci. 2021;22(4):2190. doi:10.3390/ijms22042190. |
A 50 kdyne contusion spinal cord injury with or without the drug SS‐31 was not associated with major changes in muscle mass or gene expression 14 d after injury in young male mice
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Citation:
Physiol Rep. 2021;9(4)e14751 doi:/10.14814/phy2.14751 Epub:
Not Epub Abstract:
Spinal cord injury (SCI) leads to rapid muscle atrophy due to paralysis/paresis and subsequent disuse. SS‐31 is a mitochondrial... Organism or Cell Type:
cell culture: C2C12 Citation Extract: Graham ZA, DeBerry JJ, Cardozo CP, Bamman MM. A 50 kdyne contusion spinal cord injury with or without the drug SS‐31 was not associated with major changes in muscle mass or gene expression 14 d after injury in young male mice. Physiol Rep. 2021;9(4)e14751 doi:/10.14814/phy2.14751. |
Visualization of Transcriptional Activity in Early Zebrafish Primordial Germ Cells
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Citation:
Methods Mol Biol. 2021;2218:185-194. doi: 10.1007/978-1-0716-0970-5_15 Epub:
Not Epub Abstract:
Here, we describe a fast and straightforward methodology to in vivo detect transcriptional activity in the early zebrafish germ... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D'Orazio FM, Jasiulewicz A, Hadzhiev Y, Müller F. Visualization of Transcriptional Activity in Early Zebrafish Primordial Germ Cells. Methods Mol Biol. 2021;2218:185-194. doi: 10.1007/978-1-0716-0970-5_15. |
In Vitro Induction of Teleost PGCs
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Citation:
Methods Mol Biol. 2021;2218:75-83. doi:10.1007/978-1-0716-0970-5_7 Epub:
Not Epub Abstract:
Primordial germ cells (PGCs) are unique cells in an embryo. These cells contain all genetic information and therefore represent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Robles V, Valcarce DG, Riesco MF. In Vitro Induction of Teleost PGCs. Methods Mol Biol. 2021;2218:75-83. doi:10.1007/978-1-0716-0970-5_7. |
Antisense Oligonucleotide Treatment in a Humanized Mouse Model of Duchenne Muscular Dystrophy and Highly Sensitive Detection of Dystrophin Using Western Blotting
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Citation:
Methods Mol Biol. 2021;2224:203-214. doi: 10.1007/978-1-0716-1008-4_15 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a devastating X-linked muscle disorder affecting many children. The disease is caused by... Delivery Method:
injection Organism or Cell Type:
mice Citation Extract: Maruyama R, Yokota T. Antisense Oligonucleotide Treatment in a Humanized Mouse Model of Duchenne Muscular Dystrophy and Highly Sensitive Detection of Dystrophin Using Western Blotting. Methods Mol Biol. 2021;2224:203-214. doi: 10.1007/978-1-0716-1008-4_15. |
Heterochromatin protein 1 beta (HP1β) regulates neural and neural crest development by repressing pluripotency-associated gene pou5f3.2/oct25 in Xenopus
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Citation:
Dev Dyn. 2021 Feb 17. doi: 10.1002/dvdy.319. Online ahead of print Epub:
Yes Abstract:
Background: Heterochromatin protein 1 (HP1) is associated with and plays a role in compact chromatin conformation, but the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tien CL, Mohammadparast S, Chang C. Heterochromatin protein 1 beta (HP1β) regulates neural and neural crest development by repressing pluripotency-associated gene pou5f3.2/oct25 in Xenopus. Dev Dyn. 2021 Feb 17. doi: 10.1002/dvdy.319. Online ahead of print. |
Using linkage logic theory to control dynamics of a gene regulatory network of a chordate embryo
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Citation:
Sci Rep. 2021;11(1):4001. doi:10.1038/s41598-021-83045-y Epub:
Not Epub Abstract:
Linkage logic theory provides a mathematical criterion to control network dynamics by manipulating activities of a subset of... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Kobayashi K, Maeda K, Tokuoka M, Mochizuki A, Satou Y. Using linkage logic theory to control dynamics of a gene regulatory network of a chordate embryo. Sci Rep. 2021;11(1):4001. doi:10.1038/s41598-021-83045-y. |
A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2
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Citation:
Bio Open. 2021;bio.058542 doi:10.1242/bio.058542 Epub:
Not Epub Abstract:
Protein Kinase D2 belongs to a family of evolutionarily conserved enzymes regulating several biological processes. In a forward... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Giardoglou P, Bournele D, Park M, Kanoni S, Dedoussis GV, Steinberg SF, Deloukas P, Beis D. A Zebrafish Forward Genetic Screen Identifies an Indispensible Threonine Residue in the Kinase Domain of PRKD2. Bio Open. 2021;bio.058542 doi:10.1242/bio.058542. |