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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates

Authors:
Carroll SH, Trevino CM, Li EB, Kawasaki K, Myers N, Hallett SA, Alhazmi N, Cotney J, Carstens RP, Liao EC
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.194498
Epub:
Yes
Abstract:
Irf6 and Esrp1 are important for palate development across vertebrates. In zebrafish, we found that irf6 regulates the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carroll SH, Trevino CM, Li EB, Kawasaki K, Myers N, Hallett SA, Alhazmi N, Cotney J, Carstens RP, Liao EC. An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates. Development. 2020;[Epub ahead of print] doi:10.1242/dev.194498.

Coping with DNA Double-Strand Breaks via ATM Signaling Pathway in Bovine Oocytes

Authors:
Lili Wang L, Xu X, Teng M, Zhao G, Lei A
Citation:
Int J Molec Sci. 2020;21(23):8892. doi:10.3390/ijms21238892
Epub:
Not Epub
Abstract:
As a common injury almost all cells face, DNA damage in oocytes—especially double-strand breaks (DSBs), which occur naturally...
Delivery Method:
microinjection
Organism or Cell Type:
Bos taurus (cattle) oocytes
Citation Extract:
Lili Wang L, Xu X, Teng M, Zhao G, Lei A. Coping with DNA Double-Strand Breaks via ATM Signaling Pathway in Bovine Oocytes. Int J Molec Sci. 2020;21(23):8892. doi:10.3390/ijms21238892.

In vivo, Ex Vivo, and In Vitro Approaches to Study Intermediate Filaments in the Eye Lens

Authors:
Jarrin M, Young L, Wu W, Girkin JM, Quinlan RA
Citation:
Methods Enzymol. 2016;568:581-611 Chapter 21 doi:10.1016/bs.mie.2015.09.010
Epub:
Not Epub
Abstract:
The role of the eye lens is to focus light into the retina. To perform this unique function, the ocular lens must be...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jarrin M, Young L, Wu W, Girkin JM, Quinlan RA. In vivo, Ex Vivo, and In Vitro Approaches to Study Intermediate Filaments in the Eye Lens. Methods Enzymol. 2016;568:581-611 Chapter 21 doi:10.1016/bs.mie.2015.09.010.

SRP54 mutations induce Congenital Neutropenia via dominant-negative effects on XBP1 splicing

Authors:
Schürch C, Schaefer T, Müller JS, Hanns P, Arnone M, Dumlin A, Schärer J, Sinning I, Wild K, Skokowa J, Welte K, Carapito R, Bahram S, Konantz M, Lengerke C
Citation:
Blood (2021) 137 (10): 1340–1352. doi:10.1182/blood.2020008115
Epub:
Not Epub
Abstract:
Heterozygous de novo missense variants of SRP54 were recently identified in patients with congenital neutropenia (CN),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schürch C, Schaefer T, Müller JS, Hanns P, Arnone M, Dumlin A, Schärer J, Sinning I, Wild K, Skokowa J, Welte K, Carapito R, Bahram S, Konantz M, Lengerke C. SRP54 mutations induce Congenital Neutropenia via dominant-negative effects on XBP1 splicing. Blood (2021) 137 (10): 1340–1352. doi:10.1182/blood.2020008115.

Striatal astrocytes shape behavioral flexibility via regulation of the glutamate transporter EAAT2

Authors:
Boender AJ, Bontempi L, Nava L, Pelloux Y, Tonini R
Citation:
Biol Psychiatry. 2020;[Epub ahead of print] doi:10.1016/j.biopsych.2020.11.015
Epub:
Yes
Abstract:
Background: Striatal circuits must be modulated for behavioral flexibility – the ability to adapt to environmental changes....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Boender AJ, Bontempi L, Nava L, Pelloux Y, Tonini R. Striatal astrocytes shape behavioral flexibility via regulation of the glutamate transporter EAAT2. Biol Psychiatry. 2020;[Epub ahead of print] doi:10.1016/j.biopsych.2020.11.015.

STAT3 inhibits Myocardin induced cardiac hypertrophy

Authors:
Liao X-H, Xiang Y, Li J-P, Li H, Huang Y, Shen C, Zhang Z, Zhang T-C
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.21.392902
Epub:
Not Epub
Abstract:
Background: In order to explore the molecular mechanism of cardiomyocyte-dependent myocardial gene expression and cardiomyocyte...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liao X-H, Xiang Y, Li J-P, Li H, Huang Y, Shen C, Zhang Z, Zhang T-C. STAT3 inhibits Myocardin induced cardiac hypertrophy. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.21.392902 .

Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion

Authors:
Slováková J, Sikora M, Caballero-Mancebo S, Krens SFG, Kaufmann WA, Huljev K, Heisenberg C-P
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.20.391284
Epub:
Not Epub
Abstract:
Tension of the actomyosin cell cortex plays a key role in determining cell-cell contact growth and size. The level of cortical...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Slováková J, Sikora M, Caballero-Mancebo S, Krens SFG, Kaufmann WA, Huljev K, Heisenberg C-P. Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.20.391284.

Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity

Authors:
Cambier CJ, Banik SM, Buonomo JA, Bertozzi CR
Citation:
eLife. 2020;9:e60648 doi:10.7554/eLife.60648
Epub:
Not Epub
Abstract:
Several virulence lipids populate the outer cell wall of pathogenic mycobacteria (Jackson, 2014). Phthiocerol dimycocerosate (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cambier CJ, Banik SM, Buonomo JA, Bertozzi CR. Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity. eLife. 2020;9:e60648 doi:10.7554/eLife.60648.

Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells

Authors:
Pak B, Schmitt CE, Choi W, Kim J-D, Han O, Alsiö J, Jung D-W, Williams DR, Coppieters W, Stainier DYR, Jin S-W
Citation:
Front Cell Devel Biol. 2020;8:1306. doi:10.3389/fcell.2020.589717
Epub:
Not Epub
Abstract:
Endothelial cells appear to emerge from diverse progenitors. However, to which extent their developmental origin contributes to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pak B, Schmitt CE, Choi W, Kim J-D, Han O, Alsiö J, Jung D-W, Williams DR, Coppieters W, Stainier DYR, Jin S-W. Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells. Front Cell Devel Biol. 2020;8:1306. doi:10.3389/fcell.2020.589717 .

N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

Authors:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X
Citation:
Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8
Epub:
Not Epub
Abstract:
Background and aims: Accumulating evidence suggests that the primary and acquired resistance of hepatocellular carcinoma (HCC)...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HepG2-SR
Citation Extract:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X. N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling. Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8.

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