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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance
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Citation:
Sci Rep. 2021;11:1604. doi:10.1038/s41598-021-81222-7 Epub:
Not Epub Abstract:
Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle... Delivery Method:
intramuscular i.m. or intravenous i.v. injection Organism or Cell Type:
mice C57/Bl6 Citation Extract: Eilers W, Cleasby M, Foster K. Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance. Sci Rep. 2021;11:1604. doi:10.1038/s41598-021-81222-7. |
Stimulation of hepatocarcinogenesis by activated cholangiocytes via Il17a/f1 pathway in kras transgenic zebrafish model
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Citation:
Sci Rep. 2021;11:1372. doi:10.1038/s41598-020-80621-6 Epub:
Not Epub Abstract:
It has been well known that tumor progression is dependent on secreted factors not only from tumor cells but also from other... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Helal M, Yan C, Gong Z. Stimulation of hepatocarcinogenesis by activated cholangiocytes via Il17a/f1 pathway in kras transgenic zebrafish model. Sci Rep. 2021;11:1372. doi:10.1038/s41598-020-80621-6. |
Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo
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Citation:
mBio. 2021;12(1):e02411-20. doi:10.1128/mBio.02411-20 Epub:
Not Epub Abstract:
Most antimicrobials currently in the clinical pipeline are modifications of existing classes of antibiotics and are considered... Delivery Method:
peptide-linked Organism or Cell Type:
Pseudomonas aeruginosa as biofilm or murine pneumonial infection Citation Extract: Moustafa DA, Wu AW, Zamora D, Daly SM, Sturge CR, Pybus C, Geller BL, Goldberg JB, Greenberg DE. Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo. mBio. 2021;12(1):e02411-20. doi:10.1128/mBio.02411-20. |
Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
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Citation:
Sci Rep. 2021;11:118 doi:10.1038/s41598-020-80455-2 Epub:
Not Epub Abstract:
Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C. Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. Sci Rep. 2021;11:118 doi:10.1038/s41598-020-80455-2. |
The tight junction protein Claudin-5 limits endothelial cell motility
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Citation:
J Cell Sci. 2021;134:jcs248237 doi:10.1242/jcs.248237 Epub:
Not Epub Abstract:
Steinberg's differential adhesion hypothesis suggests that adhesive mechanisms are important for sorting of cells and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Krudewig A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J. The tight junction protein Claudin-5 limits endothelial cell motility. J Cell Sci. 2021;134:jcs248237 doi:10.1242/jcs.248237. |
Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio)
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Citation:
Am J Physiol Regul Integr Comp Physiol. 2021;320(1):R55-R68. doi:10.1152/ajpregu.00215.2020 Epub:
Not Epub Abstract:
In fishes, branchial cytosolic carbonic anhydrase (CA) plays an important role in ion and acid-base regulation. The Ca17a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF. Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2021;320(1):R55-R68. doi:10.1152/ajpregu.00215.2020. |
Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Fibrinogen Disorders
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Citation:
Int J Molec Sci. 2021;22(2):1422-0067 doi:10.3390/ijms22020655 Epub:
Not Epub Abstract:
Venous thrombosis occurs in patients with quantitative and qualitative fibrinogen disorders. Injury-induced thrombosis in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fish RJ, Freire C, Di Sanza C, Neerman-Arbez M. Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Fibrinogen Disorders. Int J Molec Sci. 2021;22(2):1422-0067 doi:10.3390/ijms22020655. |
The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos
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Citation:
Front Cell Dev Biol. 2020 Dec 23;8:596069. doi: 10.3389/fcell.2020.596069. eCollection 2020 Epub:
Not Epub Abstract:
Mitochondrial membrane Protein Associated Neurodegeneration (MPAN) is a rare genetic disorder due to mutations in C19orf12 gene... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mignani L, Zizioli D, Borsani G, Monti E, Finazzi D. The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos. Front Cell Dev Biol. 2020 Dec 23;8:596069. doi: 10.3389/fcell.2020.596069. eCollection 2020. |
Yulink, predicted from evolutionary analysis, is involved in cardiac function
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Citation:
J Biomed Sci. 2021 Jan 11;28(1):7. doi: 10.1186/s12929-020-00701-7 Epub:
Not Epub Abstract:
Background: The comparative evolutionary genomics analysis was used to study the functions of novel Ka/Ks-predicted human exons... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kuo MW, Tsai HH, Wang SH, Chen YY, Yu AL, Yu J. Yulink, predicted from evolutionary analysis, is involved in cardiac function. J Biomed Sci. 2021 Jan 11;28(1):7. doi: 10.1186/s12929-020-00701-7. |
NF-Y is critical for the proper growth of zebrafish embryonic heart and its cardiomyocyte proliferation
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Citation:
Genesis. 2021 Jan 8:e23408. doi: 10.1002/dvg.23408. Online ahead of print Epub:
Yes Abstract:
The ubiquitous NF-Y gene regulates the expression of different genes in various signaling pathways. However, the function of NF... Organism or Cell Type:
zebrafish Citation Extract: Chen J. NF-Y is critical for the proper growth of zebrafish embryonic heart and its cardiomyocyte proliferation. Genesis. 2021 Jan 8:e23408. doi: 10.1002/dvg.23408. Online ahead of print. |