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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom

Authors:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer SA, Reitzel AM, Moran Y
Citation:
Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117
Epub:
Yes
Abstract:
The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model for characterizing the evolution of genes...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer SA, Reitzel AM, Moran Y. Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom. Proc Natl Acad Sci U S A. 2020;[Epub ahead of print] doi:10.1073/pnas.2011120117.

Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish

Authors:
Okamoto R, Goto I,Nishimura Y, Kobayashi I, Hashizume R, Yoshida Y, Ito R, Kobayashi Y, Nishikawa M, Ali Y, Saito S, Tanaka T, Sawa Y, Ito M, Dohi K
Citation:
PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129
Epub:
Not Epub
Abstract:
We examined a patient and her older brother who both presented with complicated severe hypertrophic cardiomyopathy (HCM) and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okamoto R, Goto I,Nishimura Y, Kobayashi I, Hashizume R, Yoshida Y, Ito R, Kobayashi Y, Nishikawa M, Ali Y, Saito S, Tanaka T, Sawa Y, Ito M, Dohi K. Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish. PLoS ONE. 2020;15(10):e0240129. doi:10.1371/journal.pone.0240129.

Respiratory responses to external ammonia in zebrafish (Danio rerio)

Authors:
Porteus C, Kumai Y, Abdallah SJ, Yew HM, Kwong RWM, Pan Y, Milsom WK, Perry SF
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822
Epub:
Yes
Abstract:
The effects of high external ammonia (HEA) exposure on breathing and the potential involvement of ammonia transporting Rh...
Organism or Cell Type:
zebrafish
Citation Extract:
Porteus C, Kumai Y, Abdallah SJ, Yew HM, Kwong RWM, Pan Y, Milsom WK, Perry SF. Respiratory responses to external ammonia in zebrafish (Danio rerio). Comp Biochem Physiol A Mol Integr Physiol. 2020;[Epub] doi:10.1016/j.cbpa.2020.110822.

The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior

Authors:
Venturini V, Pezzano F, Castro FC, Häkkinen H-M, Jiménez-Delgado S, Colomer-Rosell M, Marro M, Tolosa-Ramon Q, Paz-López S, Valverde MA, Weghuber J, Loza-Alvarez P, Krieg M, Wieser S, Ruprecht V
Citation:
Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644
Epub:
Yes
Abstract:
The physical microenvironment regulates cell behavior during tissue development and homeostasis. How single cells decode...
Organism or Cell Type:
zebrafish
Citation Extract:
Venturini V, Pezzano F, Castro FC, Häkkinen H-M, Jiménez-Delgado S, Colomer-Rosell M, Marro M, Tolosa-Ramon Q, Paz-López S, Valverde MA, Weghuber J, Loza-Alvarez P, Krieg M, Wieser S, Ruprecht V. The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior. Science. 2020;370(6514) [Epub ahead of print] doi:10.1126/science.aba2644.

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

Authors:
Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW
Citation:
J Neurosci. 2020;[Epub ahead of print] doi:10.1523/JNEUROSCI.2666-19.2020
Epub:
Yes
Abstract:
Relapse to drug use can be initiated by drug-associated cues. The intensity of cue-induced drug seeking in rodent models...
Delivery Method:
catheter to brain nucleus accumbans core (NAcore)
Organism or Cell Type:
Rat
Citation Extract:
Garcia-Keller C, Scofield MD, Neuhofer D, Varanasi S, Reeves MT, Hughes B, Anderson E, Richie CT, Mejias-Aponte C, Pickel J, Hope BT, Harvey BK, Cowan CW, Kalivas PW . Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons. J Neurosci. 2020;[Epub ahead of print] doi:10.1523/JNEUROSCI.2666-19.2020.

Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer

Authors:
Li Y, Gao X, Wei C, Guo R, Xu H, Bai Z, Zhou J, Zhu J, Wang W, Wu Y, Li J, Zhang Z, Xie X
Citation:
Aging. 2020;12. doi:10.18632/aging.103766
Epub:
Not Epub
Abstract:
Splicing dysregulation, which leads to apoptosis resistance, has been recognized as a major hallmark for tumorigenesis and...
Delivery Method:
Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
cell culture: gastric cancer lines MKN-28, SGC-7901, and MKN-45; xenograft mice
Citation Extract:
Li Y, Gao X, Wei C, Guo R, Xu H, Bai Z, Zhou J, Zhu J, Wang W, Wu Y, Li J, Zhang Z, Xie X. Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer. Aging. 2020;12. doi:10.18632/aging.103766.

Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1

Authors:
Ichikawa T, Stuckenholz C, Davidson LA
Citation:
Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y
Epub:
Not Epub
Abstract:
Classical cadherins are well-known adhesion molecules responsible for physically connecting neighboring cells and signaling...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1. Sci Rep. 2020;10:17326. doi:10.1038/s41598-020-73862-y.

β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors

Authors:
Nishiwaki Y, Masai I
Citation:
Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x
Epub:
Not Epub
Abstract:
BNip1, which functions as a t-SNARE component of the syntaxin18 complex, is localized on the ER membrane and regulates...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nishiwaki Y, Masai I. β-SNAP activity in the outer segment growth period is critical for preventing BNip1-dependent apoptosis in zebrafish photoreceptors. Sci Rep. 2020;10:17379. doi:10.1038/s41598-020-74360-x.

Zebrafish hhatla is involved in cardiac hypertrophy

Authors:
Shi X, Zhang Y, Gong Y, Chen M, Brand‐Arzamendi K, Liu X, Wen X-Y
Citation:
J Cell Physiol. 2020;[Epub ahead of print] doi:10.1002/jcp.30106
Epub:
Yes
Abstract:
Cardiac hypertrophy is a compensatory response to pathological stimuli, ultimately progresses to cardiomyopathy, heart failure...
Organism or Cell Type:
zebrafish
Citation Extract:
Shi X, Zhang Y, Gong Y, Chen M, Brand‐Arzamendi K, Liu X, Wen X-Y. Zebrafish hhatla is involved in cardiac hypertrophy. J Cell Physiol. 2020;[Epub ahead of print] doi:10.1002/jcp.30106.

Identification and characterisation of highly fluorescent pigment cells in embryos of the Arabian killifish (Aphanius dispar)

Authors:
Hamied A, Alnedawy Q, Correia A, Hacker C, Ramsdale M, Hashimoto H, Kudoh T
Citation:
iScience. 2020 Oct 13;23(11):101674. doi: 10.1016/j.isci.2020.101674. eCollection 2020 Nov 20.
Epub:
Not Epub
Abstract:
The Arabian Killifish, Aphanius dispar, is a small tropical teleost fish living in wide range of habitats in sea water and...
Delivery Method:
microinjection
Organism or Cell Type:
Aphanius dispar (Arabian killifish)
Citation Extract:
Hamied A, Alnedawy Q, Correia A, Hacker C, Ramsdale M, Hashimoto H, Kudoh T. Identification and characterisation of highly fluorescent pigment cells in embryos of the Arabian killifish (Aphanius dispar). iScience. 2020 Oct 13;23(11):101674. doi: 10.1016/j.isci.2020.101674. eCollection 2020 Nov 20..

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