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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity

Authors:
Cambier CJ, Banik SM, Buonomo JA, Bertozzi CR
Citation:
eLife. 2020;9:e60648 doi:10.7554/eLife.60648
Epub:
Not Epub
Abstract:
Several virulence lipids populate the outer cell wall of pathogenic mycobacteria (Jackson, 2014). Phthiocerol dimycocerosate (...
Link:
https://elifesciences.org/articles/60648
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cambier CJ, Banik SM, Buonomo JA, Bertozzi CR. Spreading of a mycobacterial cell surface lipid into host epithelial membranes promotes infectivity. eLife. 2020;9:e60648 doi:10.7554/eLife.60648.

Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells

Authors:
Pak B, Schmitt CE, Choi W, Kim J-D, Han O, Alsiö J, Jung D-W, Williams DR, Coppieters W, Stainier DYR, Jin S-W
Citation:
Front Cell Devel Biol. 2020;8:1306. doi:10.3389/fcell.2020.589717
Epub:
Not Epub
Abstract:
Endothelial cells appear to emerge from diverse progenitors. However, to which extent their developmental origin contributes to...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2020.589717/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pak B, Schmitt CE, Choi W, Kim J-D, Han O, Alsiö J, Jung D-W, Williams DR, Coppieters W, Stainier DYR, Jin S-W. Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells. Front Cell Devel Biol. 2020;8:1306. doi:10.3389/fcell.2020.589717 .

N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling

Authors:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X
Citation:
Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8
Epub:
Not Epub
Abstract:
Background and aims: Accumulating evidence suggests that the primary and acquired resistance of hepatocellular carcinoma (HCC)...
Link:
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-020-01281-8
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HepG2-SR
Citation Extract:
Xu J, Wan Z, Tang M, Lin Z, Jiang S, Ji L, Gorshkov K, Mao Q, Xia S, Cen D, Zheng J, Liang X, Cai X. N6-methyladenosine-modified CircRNA-SORE sustains sorafenib resistance in hepatocellular carcinoma by regulating β-catenin signaling. Mol Cancer. 2020:19(1):163. doi:10.1186/s12943-020-01281-8.

Transcriptional regulation of EMT by nuclear MMP28

Authors:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544
Epub:
Not Epub
Abstract:
Epithelial-Mesenchymal Transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.19.389544v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gouignard N, Bibonne A, Saint-Jeannet J-P, Theveneau E. Transcriptional regulation of EMT by nuclear MMP28. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.19.389544 .

Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h

Authors:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y
Citation:
Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7
Epub:
Yes
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) have been the focus of developmental and regenerative studies, yet our...
Link:
https://www.nature.com/articles/s41556-020-00604-7
Organism or Cell Type:
zebrafish
Citation Extract:
Espanola SG, Song H, Ryu E, Saxena A, Kim E-S, Manegold JE, Nasamran CA, Sahoo D, Oh C-K, Bickers C, Shin U, Grainger S, Park YH, Pandolfo L, Kang M-S, Kang S, Myung K, Cooper KL, Yelon D, Traver D, Lee Y. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nat Cell Biol. 2020;[Epub ahead of print] doi:10.1038/s41556-020-00604-7.

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells

Authors:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK
Citation:
Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6
Epub:
Not Epub
Abstract:
Alternative splicing (AS) is involved in cell fate decisions and embryonic development. However, regulation of these processes...
Link:
https://www.nature.com/articles/s41467-020-19698-6
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Jin L, Chen Y, Crossman DK, Datta A, Vu T, Mobley JA, Basu MK, Scarduzio M, Wang H, Chang C, Datta PK. STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells. Nat Comm. 2020;11(1):5941. doi:10.1038/s41467-020-19698-6.

PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA

Authors:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM
Citation:
Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021
Epub:
Yes
Abstract:
Duchenne Muscular Dystrophy (DMD) is a severe genetic disorder caused by mutations in the DMD gene. Absence of dystrophin...
Link:
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(20)30619-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lambert MR, Spinazzola JM, Widrick JJ, Pakula A, Conner JR, Chin JE, Owens JM, Kunkel LM. PDE10A inhibition reduces the manifestation of pathology in DMD zebrafish and represses the genetic modifier PITPNA. Mol Ther. 2020;[Epub ahead of print] doi:10.1016/j.ymthe.2020.11.021.

The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network

Authors:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827
Epub:
Yes
Abstract:
\Understanding how complex organ systems are assembled from simple embryonic tissues is a major challenge. Across the animal...
Link:
https://dev.biologists.org/content/early/2020/11/15/dev.185827
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
cell culture: Gallus gallus (chick) somite tissue
Citation Extract:
Grocott T, Lozano-Velasco E, Mok GF, Münsterberg AE. The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network. Development. 2020;[Epub ahead of print] doi:10.1242/dev.185827.

Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis

Authors:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P
Citation:
Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363
Epub:
Not Epub
Abstract:
Gastrulation drives the establishment of three germ layers and embryonic axes during frog embryonic development. Mesodermal...
Link:
https://www.mdpi.com/2073-4425/11/11/1363/htm
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Huang X, Zhang L, Yang S, Zhang Y, Wu M, Chen P. Hes5.9 Coordinate FGF and Notch Signaling to Modulate Gastrulation via Regulating Cell Fate Specification and Cell Migration in Xenopus tropicalis. Genes. 2020:11(11):2073-4425. doi:10.3390/genes11111363.

Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching

Authors:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099
Epub:
Not Epub
Abstract:
Interstitial collateral branching of axons is a critical component in the development of functional neural circuits. Axon...
Link:
https://www.biorxiv.org/content/10.1101/2020.11.16.384099v1
Organism or Cell Type:
cell culture: chick spinal neurons
Citation Extract:
Kundu T, Das SS, Kumar DS, Sewatkar LK, Ghose A. Antagonistic activities of Fmn2 and ADF regulate axonal F-actin patch dynamics and the initiation of collateral branching. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.16.384099.

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