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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk
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Citation:
Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881 Epub:
Not Epub Abstract:
Lymphatic vascular development involves specification of lymphatic endothelial progenitors that subsequently undergo sprouting... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Grimm L, Nakajima H, Chaudhury S, Bower NI, Okuda KS, Cox AG, Harvey NL, Koltowska K, Mochizuki N, Hogan BM. Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk. Elife. 2019 Apr 30;8:e42881. doi: 10.7554/eLife.42881. |
Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923 Epub:
Not Epub Abstract:
We previously identified a deletion on chromosome 16p12.1 that is mostly inherited and associated with multiple... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pizzo L, Lasser M, Yusuff T, Jensen M, Ingraham P, Huber E, Singh MD, Monahan C, Iyer J, Inshya Desai, Karthikeyan S, Dagny J. Gould DJ, Yennawar S, Weiner AT, Krishnan A, Rolls M, Lowery LA, Girirajan S. Functional assessment of the “two-hit” model for neurodevelopmental defects in Drosophila and X. laevis. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.14.295923 . |
TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit
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Citation:
FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print Epub:
Yes Abstract:
Sprouting angiogenesis is a highly coordinately process controlled by vascular endothelial growth factor receptor (VEGFR)-Notch... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wang Y, Singh AR, Zhao Y, Du T, Huang Y, Wan X, Mukhopadhyay D, Wang Y, Wang N, Zhang P. TRIM28 regulates sprouting angiogenesis through VEGFR-DLL4-Notch signaling circuit. FASEB J. 2020 Sep 12. doi: 10.1096/fj.202000186RRR. Online ahead of print. |
Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707 Epub:
Not Epub Abstract:
Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Danesin C, Darche-Gabinaud R, Escalas N, Bouguetoch V, Cochard P, Al Oustah A, Ohayon D, Glise B, Soula C. Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.20.258707. |
The N-Glycome regulates the endothelial-to-hematopoietic transition
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/602912 Epub:
Not Epub Abstract:
Hematopoietic stem and progenitor cells (HSPCs) that establish and maintain the blood system in adult vertebrates arise from... Organism or Cell Type:
zebrafish Citation Extract: Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. The N-Glycome regulates the endothelial-to-hematopoietic transition. bioRxiv. 2020;[preprint] doi:10.1101/602912 . |
Glypican4 mediates Wnt transport between germ layers via signaling filopodia
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.288613 Epub:
Not Epub Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu B, Balaraju AK, Rodriguez JJ, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican4 mediates Wnt transport between germ layers via signaling filopodia. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.08.288613. |
Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a
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Citation:
Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print Epub:
Not Epub Abstract:
Diamond Blackfan Anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wilkes MC, Siva K, Varetti G, Mercado J, Wentworth EP, Perez C, Saxena M, Kam S, Kapur S, Chen J, Narla A, Glader B, Lin S, Serrano M, Flygare J, Sakamoto KM. Metformin-induced suppression of NLK improves erythropoiesis in pre-clinical models of Diamond Blackfan Anemia through induction of miR-26a. Exp Hematol. 2020 Sep 11:S0301-472X(20)30552-X. doi: 10.1016/j.exphem.2020.09.187. Online ahead of print. |
R-spondins are BMP receptor antagonists in early embryonic development
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.09.10.287607 Epub:
Not Epub Abstract:
BMP signalling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Seidl C, Sun R, Glinka A, Niehrs C. R-spondins are BMP receptor antagonists in early embryonic development. bioRxiv. 2020;[preprint] doi:10.1101/2020.09.10.287607 . |
In vivo Pharmacokinetic and Biodistribution profile of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides
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Citation:
Poster at 2015 Oligonucleotide Therapeutics Society meeting Epub:
Not Epub Abstract:
Antisense oligonucleotide (AON) induced exon skipping is one of the most promising strategies for treating Duchene muscular... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Burki U, Blain A, Greally E, O’Donovan L, Gait M, Laval S, Straub V. In vivo Pharmacokinetic and Biodistribution profile of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides. Poster at 2015 Oligonucleotide Therapeutics Society meeting. |
Transgenerational inheritance of impaired larval T cell development in zebrafish
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Citation:
Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9 Epub:
Not Epub Abstract:
Evidence for transgenerational inheritance of epigenetic information in vertebrates is scarce. Aberrant patterns of DNA... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iwanami N, Lawir DF, Sikora K, O Meara C, Takeshita K, Schorpp M, Boehm T. Transgenerational inheritance of impaired larval T cell development in zebrafish. Nat Commun. 2020 Sep 9;11(1):4505. doi: 10.1038/s41467-020-18289-9. |