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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Cohesin components Stag1 and Stag2 differentially influence haematopoietic mesoderm development in zebrafish embryos
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.19.346122 Epub:
Not Epub Abstract:
Cohesin is a multiprotein complex made up of core subunits Smc1, Smc3 and Rad21, and either Stag1 or Stag2. Normal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ketharnathan S, Labudina A, Horsfield JA. Cohesin components Stag1 and Stag2 differentially influence haematopoietic mesoderm development in zebrafish embryos. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.19.346122. |
RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.14.338715 Epub:
Not Epub Abstract:
Neural crest development is transcriptionally controlled via sequential activation of gene regulatory networks (GRNs). Recent... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hutchins EJ, Chacon J, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.14.338715 . |
hox13 genes are required for mesoderm formation and axis elongation during early zebrafish development
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Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.185298 Epub:
Yes Abstract:
The early vertebrate embryo extends from anterior to posterior due to the addition of neural and mesodermal cells from a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ye Z, Kimelman D. hox13 genes are required for mesoderm formation and axis elongation during early zebrafish development. Development. 2020;[Epub ahead of print] doi:10.1242/dev.185298. |
Traditional African remedies induce hemolysis in a glucose-6-phopshate dehydrogenase deficient zebrafish model
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Citation:
Sci Rep. 2020;10(1):19172 doi:10.1038/s41598-020-75823-x Epub:
Not Epub Abstract:
Traditional remedies are widely used throughout Africa in routine care for infants. However, such remedies could have... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Arogbokun O, Shevik M, Slusher T, Farouk Z, Elfstrum A, Weber J, Cusick SE, Lund T. Traditional African remedies induce hemolysis in a glucose-6-phopshate dehydrogenase deficient zebrafish model. Sci Rep. 2020;10(1):19172 doi:10.1038/s41598-020-75823-x. |
A serpin is required for ectomesoderm, a hallmark of spiralian development
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Citation:
Dev Biol. 2020 Oct 24:S0012-1606(20)30282-7. doi: 10.1016/j.ydbio.2020.10.011. Online ahead of print Epub:
Yes Abstract:
Among animals, diploblasts contain two germ layers, endoderm and ectoderm, while triploblasts have a distinct third germ layer... Delivery Method:
microinjection Organism or Cell Type:
Tritia obsoleta (previously Ilyanassa obsoleta) gastropod Citation Extract: Wu L, Lambert JD. A serpin is required for ectomesoderm, a hallmark of spiralian development. Dev Biol. 2020 Oct 24:S0012-1606(20)30282-7. doi: 10.1016/j.ydbio.2020.10.011. Online ahead of print. |
R-spondins are BMP receptor antagonists in Xenopus early embryonic development
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Citation:
Nat Commun. 2020;11:5570. doi:10.1038/s41467-020-19373-w Epub:
Not Epub Abstract:
BMP signaling plays key roles in development, stem cells, adult tissue homeostasis, and disease. How BMP receptors are... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lee H, Seidl C, Sun R, Glinka A, Niehrs C. R-spondins are BMP receptor antagonists in Xenopus early embryonic development. Nat Commun. 2020;11:5570. doi:10.1038/s41467-020-19373-w. |
Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency
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Citation:
PLoS Genet. 2020 Nov 2;16(11):e1009088. doi: 10.1371/journal.pgen.1009088. eCollection 2020 Nov Epub:
Not Epub Abstract:
Mutations in the molecular co-chaperone Bcl2-associated athanogene 3 (BAG3) are found to cause dilated cardiomyopathy (DCM),... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Diofano F, Weinmann K, Schneider I, Thiessen KD, Rottbauer W, Just S. Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency. PLoS Genet. 2020 Nov 2;16(11):e1009088. doi: 10.1371/journal.pgen.1009088. eCollection 2020 Nov. |
TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.27.356782 Epub:
Not Epub Abstract:
Trimethylguanosine synthase 1 (TGS1) is a highly conserved enzyme that converts the 5’ mono-methylguanosine cap of snRNAs to a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Hammerschmidt M, De Pittà C, Gabriele Sales G, Salzman J, Pellizzoni L, Wirth B, Di Schiavi E, Gatti M, Artandi SE, Raffa GD. TGS1 controls snRNA 3’ end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.27.356782. |
Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification
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Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.10.30.362541 Epub:
Not Epub Abstract:
The Wnt pathway activates target genes by controlling the b-catenin-T-cell factor (TCF) transcriptional complex during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Reis AH, Sokol SY. Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification. bioRxiv. 2020;[preprint] doi:/10.1101/2020.10.30.362541 . |
Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.11.01.362053 Epub:
Not Epub Abstract:
Mesendodermal specification is one of the earliest events in embryogenesis, where cells first acquire distinct identities. Cell... Organism or Cell Type:
Xenopus Citation Extract: Jansen C, Paraiso K, Zhou J, Blitz IL, Fish M, Charney R, Cho JS, Yasuoka Y, Sudou N, Bright AR, Wlizla M, Veenstra GJC, Taira M, Zorn A, Mortazavi A, Cho KWY. Uncovering the mesendoderm gene regulatory network through multi-omic data integration. bioRxiv. 2020;[preprint] doi:10.1101/2020.11.01.362053. |