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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Histone variant dictates fate biasing of neural crest cells to melanocyte lineage

Authors:
Raja DA, Subramaniam Y, Aggarwal A, Gotherwal V, Babu A, Tanwar J, Motiani RK, Sivasubbu S, Gokhale RS, Natarajan VT
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.182576
Epub:
Yes
Abstract:
In the neural crest lineage, progressive fate-restriction and stem cell assignment are critical for both development and...
Link:
https://dev.biologists.org/content/early/2020/02/13/dev.182576
Organism or Cell Type:
zebrafish
Citation Extract:
Raja DA, Subramaniam Y, Aggarwal A, Gotherwal V, Babu A, Tanwar J, Motiani RK, Sivasubbu S, Gokhale RS, Natarajan VT. Histone variant dictates fate biasing of neural crest cells to melanocyte lineage. Development. 2020;[Epub ahead of print] doi:10.1242/dev.182576.

New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration

Authors:
Pasteuning-Vuhman S, Boertje-van der Meulen JW, Putten MV, Overzier M, Ten Dijke P, Kielbasa SM, Arindrarto W, Wolterbeek R, Lezhnina KV, Ozerov IV, Aliper AM, Hoogaars WM, Aartsma-Rus A, Loomans CJM
Citation:
FASEB J. 2017 Jan;31(1):238-255. doi: 10.1096/fj.201600675r
Epub:
Not Epub
Abstract:
Skeletal muscle fibrosis and impaired muscle regeneration are major contributors to muscle wasting in Duchenne muscular...
Link:
https://www.fasebj.org/doi/full/10.1096/fj.201600675r
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: C2C12 myoblasts, 4-wk-old male mdx or 3-mo-old male C57BL/6Jico WT mice
Citation Extract:
Pasteuning-Vuhman S, Boertje-van der Meulen JW, Putten MV, Overzier M, Ten Dijke P, Kielbasa SM, Arindrarto W, Wolterbeek R, Lezhnina KV, Ozerov IV, Aliper AM, Hoogaars WM, Aartsma-Rus A, Loomans CJM. New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration. FASEB J. 2017 Jan;31(1):238-255. doi: 10.1096/fj.201600675r.

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42

Authors:
Hung IC, Chen TM, Lin JP, Tai YL, Shen TL, Lee SJ
Citation:
Open Biol. 2020 Feb;10(2):190273. doi: 10.1098/rsob.190273. Epub 2020 Feb 26
Epub:
Not Epub
Abstract:
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and...
Link:
https://royalsocietypublishing.org/doi/full/10.1098/rsob.190273
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hung IC, Chen TM, Lin JP, Tai YL, Shen TL, Lee SJ. Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42. Open Biol. 2020 Feb;10(2):190273. doi: 10.1098/rsob.190273. Epub 2020 Feb 26.

Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces

Authors:
Ghate K, Mutalik SP, Sthanam LK, Sen S, Ghose A
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.21.959759
Epub:
Not Epub
Abstract:
Growth cone - mediated axonal outgrowth and accurate synaptic targeting are central to brain morphogenesis. Translocation of...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.21.959759v1
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick) spinal cord explants
Citation Extract:
Ghate K, Mutalik SP, Sthanam LK, Sen S, Ghose A. Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.21.959759.

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network

Authors:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KWY, Zorn AM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.19.956565
Epub:
Not Epub
Abstract:
Lineage specification depends on the integration of lineage-determining transcription factors (TFs) and signaling effectors on...
Link:
https://www.biorxiv.org/content/10.1101/2020.02.19.956565v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KWY, Zorn AM. Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.19.956565 .

Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development

Authors:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R
Citation:
Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1
Epub:
Yes
Abstract:
KIAA1429 (also known as vir-like m6A methyltransferase-associated protein (VIRMA)), a newly identified component of the RNA m6A...
Link:
https://www.nature.com/articles/s41418-020-0516-1
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R. Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development. Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1.

Identification of mecciRNAs and their roles in the mitochondrial entry of proteins

Authors:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Citation:
Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9
Epub:
Yes
Abstract:
Mammalian mitochondria have small genomes encoding very limited numbers of proteins. Over one thousand proteins and noncoding...
Link:
https://www.ncbi.nlm.nih.gov/pubmed/32048164
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: 293T
Citation Extract:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G. Identification of mecciRNAs and their roles in the mitochondrial entry of proteins. Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9.

Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio)

Authors:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY
Citation:
Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019
Epub:
Yes
Abstract:
Isotocin controls ion regulation through modulating the functions of ionocytes (also called mitochondria-rich cells or chloride...
Link:
https://journals.physiology.org/doi/abs/10.1152/ajpregu.00307.2019
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY. Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019.

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

Authors:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO
Citation:
Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9
Epub:
Not Epub
Abstract:
The sarco-endoplasmic reticulum (SR/ER) plays an important role in the development and progression of many heart diseases....
Link:
https://www.nature.com/articles/s41467-019-14143-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9.

Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits

Authors:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML
Citation:
EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print]
Epub:
Yes
Abstract:
Various species of non‐coding RNAs (ncRNAs) are enriched in specific subcellular compartments, but the mechanisms orchestrating...
Link:
https://www.embopress.org/doi/10.15252/embj.2019102513
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
Xenopus laevis embryo and cell culture
Citation Extract:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML. Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits. EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print].

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