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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12179 scientific papers returned from the database with the search filters currently being used below.

Tissue-Specific Requirement for the GINS Complex During Zebrafish Development

Authors:
Varga M, Csályi K, Bertyák I, Menyhárd DK, Poole RJ, Cerveny KL, Kövesdi D, Barátki B, Rouse H, Vad Z, Hawkins TA, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW
Citation:
Front Cell Dev Biol. 2020;8:373. doi:10.3389/fcell.2020.00373
Epub:
Not Epub
Abstract:
Efficient and accurate DNA replication is particularly critical in stem and progenitor cells for successful proliferation and...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2020.00373/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Varga M, Csályi K, Bertyák I, Menyhárd DK, Poole RJ, Cerveny KL, Kövesdi D, Barátki B, Rouse H, Vad Z, Hawkins TA, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW. Tissue-Specific Requirement for the GINS Complex During Zebrafish Development. Front Cell Dev Biol. 2020;8:373. doi:10.3389/fcell.2020.00373.

Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta

Authors:
Yvernogeau L, Klaus A, Maas J, Morin-Poulard I, Weijts B, Schulte-Merker S, Berezikov E, Junker JP, Robin C
Citation:
Blood. 2020;136(7):831-844. doi:10.1182/blood.2019004446
Epub:
Not Epub
Abstract:
The defined location of a stem cell within a niche regulates its fate, behavior and molecular identity via a complex extrinsic...
Link:
https://ashpublications.org/blood/article-abstract/doi/10.1182/blood.2019004446/457791/Multispecies-RNA-tomography-reveals-regulators-of
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yvernogeau L, Klaus A, Maas J, Morin-Poulard I, Weijts B, Schulte-Merker S, Berezikov E, Junker JP, Robin C. Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta. Blood. 2020;136(7):831-844. doi:10.1182/blood.2019004446.

Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain

Authors:
Liu D, Yang F, Liu Z, Wang J, Huang W, Meng W, Billadeau DD, Sun Q, Mo X, Jia D
Citation:
PLoS Biol. 2020;18(5):e3000746. doi:10.1371/journal.pbio.3000746
Epub:
Not Epub
Abstract:
Members of the Tre2-Bub2-Cdc16 (TBC) family often function to regulate membrane trafficking and to control signaling...
Link:
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000746
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu D, Yang F, Liu Z, Wang J, Huang W, Meng W, Billadeau DD, Sun Q, Mo X, Jia D. Structure of TBC1D23 N-terminus reveals a novel role for rhodanese domain. PLoS Biol. 2020;18(5):e3000746. doi:10.1371/journal.pbio.3000746.

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development

Authors:
Wolf EJ, Miles A, Lee ES, Nabeel-Shah S, Greenblatt JF, Palazzo AF, Tropepe V, Emili A
Citation:
Cell Rep. 2020;31(8):107693. doi:10.1016/j.celrep.2020.107693
Epub:
Not Epub
Abstract:
The mammalian mRNA nuclear export process is thought to terminate at the cytoplasmic face of the nuclear pore complex through...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30646-X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wolf EJ, Miles A, Lee ES, Nabeel-Shah S, Greenblatt JF, Palazzo AF, Tropepe V, Emili A. MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development. Cell Rep. 2020;31(8):107693. doi:10.1016/j.celrep.2020.107693.

Safety, Tolerability, and Efficacy of Viltolarsen in Boys With Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping

Authors:
Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, Smith EC, McDonald CM, Zaidman CM, Morgenroth LP, Osaki H, Satou Y, Yamashita T, Hoffman EP, for the CINRG DNHS Investigators
Citation:
JAMA Neurology. 2020;[Epub] doi:10.1001/jamaneurol.2020.1264
Epub:
Yes
Abstract:
Importance: An unmet need remains for safe and efficacious treatments for Duchenne muscular dystrophy (DMD). To date, there...
Link:
https://jamanetwork.com/journals/jamaneurology/fullarticle/2766519
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, Smith EC, McDonald CM, Zaidman CM, Morgenroth LP, Osaki H, Satou Y, Yamashita T, Hoffman EP, for the CINRG DNHS Investigators. Safety, Tolerability, and Efficacy of Viltolarsen in Boys With Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping. JAMA Neurology. 2020;[Epub] doi:10.1001/jamaneurol.2020.1264.

Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos

Authors:
Xiong KM, Peterson RE, Heideman W
Citation:
Mol Pharmacol. 2008 Dec;74(6):1544-53. doi:10.1124/mol.108.050435
Epub:
Not Epub
Abstract:
Exposure to environmental contaminants can disrupt normal development of the early vertebrate skeleton. 2,3,7,8-...
Link:
http://molpharm.aspetjournals.org/content/74/6/1544.short
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiong KM, Peterson RE, Heideman W. Aryl hydrocarbon receptor-mediated down-regulation of sox9b causes jaw malformation in zebrafish embryos. Mol Pharmacol. 2008 Dec;74(6):1544-53. doi:10.1124/mol.108.050435.

Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks

Authors:
Zhou Q, Perovic T, Fechner I, Edgar LT, Hoskins PR, Gerhardt H, Krüger T, Bernabeu MO
Citation:
J R Soc Interface. 2021 Jun;18(179):20210113. doi: 10.1098/rsif.2021.0113. Epub 2021 Jun 23. PMID: 34157895; PMCID: PMC8220266
Epub:
Not Epub
Abstract:
Sprouting angiogenesis is an essential vascularization mechanism consisting of sprouting and remodelling. The remodelling phase...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8220266/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Q, Perovic T, Fechner I, Edgar LT, Hoskins PR, Gerhardt H, Krüger T, Bernabeu MO. Association between erythrocyte dynamics and vessel remodelling in developmental vascular networks. J R Soc Interface. 2021 Jun;18(179):20210113. doi: 10.1098/rsif.2021.0113. Epub 2021 Jun 23. PMID: 34157895; PMCID: PMC8220266.

Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function

Authors:
Stanicek L, Lozano-Vidal N, Bink DI, Hooglugt A, Yao W, Wittig I, van Rijssel J, van Buul JD, van Bergen A, Klems A, Ramms AS, Le Noble F, Hofmann P, Szulcek R, Wang S, Offermanns S, Ercanoglu MS, Kwon H-B, Stainier D, Huveneers S, Kurian L, Dimmeler S, Boon RA
Citation:
Commun Biol. 3030;3:265 doi:10.1038/s42003-020-0987-0
Epub:
Not Epub
Abstract:
Blood vessels are constantly exposed to shear stress, a biomechanical force generated by blood flow. Normal shear stress...
Link:
https://www.nature.com/articles/s42003-020-0987-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stanicek L, Lozano-Vidal N, Bink DI, Hooglugt A, Yao W, Wittig I, van Rijssel J, van Buul JD, van Bergen A, Klems A, Ramms AS, Le Noble F, Hofmann P, Szulcek R, Wang S, Offermanns S, Ercanoglu MS, Kwon H-B, Stainier D, Huveneers S, Kurian L, Dimmeler S, Boon RA. Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function. Commun Biol. 3030;3:265 doi:10.1038/s42003-020-0987-0.

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

Authors:
Langevin C, Aleksejeva E, Houel A, Briolat V, Torhy C, Lunazzi A, Levraud J-P, Boudinot P
Citation:
Front Immunol. 2017;8:617. doi: 10.3389/fimmu.2017.00617
Epub:
Not Epub
Abstract:
Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate...
Link:
https://www.frontiersin.org/articles/10.3389/fimmu.2017.00617/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Langevin C, Aleksejeva E, Houel A, Briolat V, Torhy C, Lunazzi A, Levraud J-P, Boudinot P. FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection. Front Immunol. 2017;8:617. doi: 10.3389/fimmu.2017.00617.

Behavioral And Physiological Analysis In A Zebrafish Model Of Epilepsy

Authors:
de Calbiac H, Dabacan A, Muresan R, Kabashi E, Ciura S
Citation:
J Vis Exp. 2021 Oct 19;(176). doi: 10.3791/58837
Epub:
Not Epub
Abstract:
Epilepsy represents one of the most common neurological disorders, affecting an estimated 50 million people worldwide. Recent...
Link:
hhttps://www.jove.com/v/58837/behavioral-and-physiological-analysis-in-a-zebrafish-model-of-epilepsy
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Calbiac H, Dabacan A, Muresan R, Kabashi E, Ciura S. Behavioral And Physiological Analysis In A Zebrafish Model Of Epilepsy. J Vis Exp. 2021 Oct 19;(176). doi: 10.3791/58837.

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