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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish
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Citation:
Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20 Epub:
Not Epub Abstract:
The sex-determining region Y-box 2 (Sox2) is related not only to pluripotency, but also to cell proliferation. Zebrafish can... Organism or Cell Type:
zebrafish Citation Extract: Ogai K, Nakatani K, Hisano S, Sugitani K, Koriyama Y, Kato S. Function of Sox2 in ependymal cells of lesioned spinal cords in adult zebrafish. Neurosci Res. 2014 Nov;88:84-7. doi: 10.1016/j.neures.2014.07.010. Epub 2014 Aug 20. |
Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation
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Citation:
Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30 Epub:
Not Epub Abstract:
In vertebrates that have been examined to date, the sexual identity of germ cells is determined by the sex of gonadal somatic... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Nishimura T, Herpin A, Kimura T, Hara I, Kawasaki T, Nakamura S, Yamamoto Y, Saito TL, Yoshimura J, Morishita S, Tsukahara T, Kobayashi S, Naruse K, Shigenobu S, Sakai N, Schartl M, Tanaka M. Analysis of a novel gene, Sdgc, reveals sex chromosome-dependent differences of medaka germ cells prior to gonad formation. Development. 2014 Sep;141(17):3363-9. doi: 10.1242/dev.106864. Epub 2014 Jul 30. |
Interpretable Deep Learning for De Novo Design of Cell-Penetrating Abiotic Polymers
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.10.036566 Epub:
Not Epub Abstract:
There are more amino acid permutations within a 40-residue sequence than atoms on Earth. This vast chemical search space... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa, human renal proximal tublule epithelial cells, mice Citation Extract: Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gomez-Bombarelli R, Pentelute BL.. Interpretable Deep Learning for De Novo Design of Cell-Penetrating Abiotic Polymers. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.10.036566. |
Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6
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Citation:
Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print] Epub:
Yes Abstract:
Skin pigmentation is a highly heterogeneous trait with diverse consequences worldwide. SLC24A5, encoding a potent K+ -dependent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yousaf S, Sethna S, Chaudhary MA, Shaikh RS, Riazuddin S, Ahmed ZM. Molecular characterization of SLC24A5 variants and evaluation of Nitisinone treatment efficacy in a zebrafish model of OCA6. Pigment Cell Melanoma Res. 2020 Apr 9. doi: 10.1111/pcmr.12879. [Epub ahead of print]. |
Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization
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Citation:
J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print] Epub:
Not Epub Abstract:
Reciprocal changes in histone lysine methylation/demethylation of M(LPS + IFN-γ)/M(IL-10) genes is one of the factors that... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Parmar N, Chandrakar P, Kar S. Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization. J Immunol. 2020;204 (10) 2762-2778. doi: 10.4049/jimmunol.1900251. [Epub ahead of print]. |
Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling
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Citation:
PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696 Epub:
Not Epub Abstract:
It is well known that various developmental signals play diverse roles in hematopoietic stem and progenitor cell (HSPC)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Heng J, Lv P, Zhang Y, Cheng X, Wang L, Ma D, Liu F. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling. PLoS Biol. 2020;18(4):e3000696. doi:10.1371/journal.pbio.3000696. |
Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B
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Citation:
PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690 Epub:
Not Epub Abstract:
Loss-of-function mutations in the human coagulation factor 9 (F9) gene lead to hemophilia B. Here, we dissected the... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Krooss S, Werwitzke S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B. PLoS Genet. 2020;16(4):e1008690. doi:10.1371/journal.pgen.1008690. |
The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I
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Citation:
Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969 Epub:
Not Epub Abstract:
During mitotic prophase, cohesins are removed from chromosome arms by Wapl to ensure faithful sister chromatid separation.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Zhou C, Miao Y, Cui Z, ShiYang X, Zhang Y, Xiong B. The cohesin release factor Wapl interacts with Bub3 to govern SAC activity in female meiosis I. Sci Adv. 2020;6(15):eaax3969. doi:10.1126/sciadv.aax3969. |
Piezo1 and outflow tract and aortic valve development
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Citation:
J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013 Epub:
Yes Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Collod-Béroud G, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 and outflow tract and aortic valve development. J Molec Cell Cardiol. 2020;[Epub] doi:10.1016/j.yjmcc.2020.03.013. |
Alternative splicing is a developmental switch for hTERT expression
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022087 Epub:
Not Epub Abstract:
High telomerase activity is restricted to the blastocyst stage of embryonic development when telomere length is reset, and is... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Penev A, Bazley A, Shen M, Boeke JD, Savage SA, Sfeir A. Alternative splicing is a developmental switch for hTERT expression. bioRxiv. 2020;[preprint] doi:10.1101/2020.04.02.022087. |