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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.101071 Epub:
Not Epub Abstract:
Genetic variants associated with type 2 diabetes (T2D) risk affect gene regulation in metabolically relevant tissues, such as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.101071 . |
Cadherin-11 is required for neural crest determination and survival
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.066613 Epub:
Not Epub Abstract:
Neural crest (NC) cells are multipotent embryonic cells that form melanocytes, craniofacial bone and cartilage, and the... Delivery Method:
injection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Manohar S, Camacho-Magallanes A, Rogers CD. Cadherin-11 is required for neural crest determination and survival. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.066613. |
Zygotic Vsx1 Plays a Key Role in Defining V2a Interneuron Sub-Lineage by Directly Repressing tal1 Transcription in Zebrafish
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Citation:
Int J Mol Sci. 2020;21(10):2020. doi:10.3390/ijms21103600 Epub:
Not Epub Abstract:
In the spinal cord, excitatory V2a and inhibitory V2b interneurons are produced together by the final division of common P2... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang Q, Xu H, Zhao W, Zheng J, Sun L, Luo C. Zygotic Vsx1 Plays a Key Role in Defining V2a Interneuron Sub-Lineage by Directly Repressing tal1 Transcription in Zebrafish. Int J Mol Sci. 2020;21(10):2020. doi:10.3390/ijms21103600. |
Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism
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Citation:
Horm Res Paediatr. 2020;[Epub aheaed of print] doi:10.1159/000507114 Epub:
Yes Abstract:
Background: Congenital primary hypothyroidism (CH) is the most common endocrine disorder in neonates. Methods: To identify... Organism or Cell Type:
Xenopus laevis Citation Extract: Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M. Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism. Horm Res Paediatr. 2020;[Epub aheaed of print] doi:10.1159/000507114. |
Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish
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Citation:
eLife. 2020;9:e54935. doi:10.7554/eLife.54935 Epub:
Not Epub Abstract:
Progressive telomere shortening during lifespan is associated with restriction of cell proliferation, genome instability and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: El Maï M, Marzullo M, de Castro IP, Ferreira MG. Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. eLife. 2020;9:e54935. doi:10.7554/eLife.54935. |
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome
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Citation:
Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print Epub:
Yes Abstract:
We report truncating de novo variants in specific exons of FBRSL1 in three unrelated children with an overlapping syndromic... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmüller J, Nürnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S. De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome. Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print. |
The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology
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Citation:
Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096 Epub:
Yes Abstract:
Mutations of the RNA-granule component TDRD7 (OMIM: 611258) cause pediatric cataract. We applied an integrated approach to... Organism or Cell Type:
Xenopus tropicalis Citation Extract: Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096. |
RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function
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Citation:
Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2 Epub:
Not Epub Abstract:
Background: Vertebrate early embryogenesis is initially directed by a set of maternal RNAs and proteins, yet the mechanisms... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, Sun B-F, Yang Y, Zhang N, Zhao Y-L, Wang H-L, Liu F, Zhang QC, Yang Y-G. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2. |
Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012 Epub:
Not Epub Abstract:
Asymmetric cell division (ACD), which produces two daughters with different fates, is fundamental for generating cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao X, Tong K, Chen X, Yang B, Li Q, Dai Z, Shi X, Seiple I, Huang B, Guo S. Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012 . |
Mycobacteria inhibit neutrophil recruitment to avoid neutrophil-assisted killing by macrophages
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Citation:
bioRxiv, 2020;[preprint] doi:10.1101/2020.05.14.096032 Epub:
Not Epub Abstract:
Neutrophils migrate rapidly to sites of bacterial infection where they mount critical first-line defenses. Puzzlingly,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramakrishnan L, Candel S. Mycobacteria inhibit neutrophil recruitment to avoid neutrophil-assisted killing by macrophages. bioRxiv, 2020;[preprint] doi:10.1101/2020.05.14.096032. |