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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels

Authors:
Greenwood IA, Stott JB
Citation:
Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573
Epub:
Not Epub
Abstract:
Within the vasculature Kv7 channels are key regulators of basal tone and contribute to a variety of receptor mediated...
Link:
https://www.frontiersin.org/articles/10.3389/fphys.2019.01573/full
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: rat primary renal arteries
Citation Extract:
Greenwood IA, Stott JB. The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573.

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

Authors:
Cunningham CM, Bellipanni G, Habas R, Balciunas D
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211
Epub:
Not Epub
Abstract:
Two complimentary approaches are widely used to study gene function in zebrafish: induction of genetic mutations, usually using...
Link:
https://www.biorxiv.org/content/10.1101/2020.01.12.903211v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211 .

Slc7a14 Is Indispensable in Zebrafish Retinas

Authors:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB
Citation:
Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019
Epub:
Not Epub
Abstract:
Previous study has identified SLC7A14 as a new causative gene of retinitis pigmentosa (RP). However, the role of SLC7A14 has...
Link:
https://www.frontiersin.org/articles/10.3389/fcell.2019.00333/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB. Slc7a14 Is Indispensable in Zebrafish Retinas. Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019.

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Authors:
El-Maï M, Marzullo M, de Castro IP, Ferreira MG
Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603
Epub:
Not Epub
Abstract:
Progressive telomere shortening during lifespan is associated with increased genome instability, block to cell proliferation...
Link:
https://www.biorxiv.org/content/10.1101/2020.01.10.901603v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
El-Maï M, Marzullo M, de Castro IP, Ferreira MG. Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish. bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603.

Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis

Authors:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B
Citation:
FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30
Epub:
Not Epub
Abstract:
Cell morphology and tissue integrity are essential for embryogenesis. Caveolins are membrane proteins that induce the formation...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1096/fj.201901281R
Delivery Method:
microinjection
Organism or Cell Type:
Ciona sp.
Citation Extract:
Bhattachan P, Rae J, Yu H, Jung W, Wei J, Parton RG, Dong B. Ascidian caveolin induces membrane curvature and protects tissue integrity and morphology during embryogenesis. FASEB J. 2020 Jan;34(1):1345-1361. doi: 10.1096/fj.201901281R. Epub 2019 Nov 30.

METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition

Authors:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R
Citation:
Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print]
Epub:
Not Epub
Abstract:
N6-methyladenosine (m6A) is the most prevalent epigenetic modification of messenger RNA (mRNA) in higher eukaryotes; this...
Link:
https://www.tandfonline.com/doi/abs/10.1080/15384101.2019.1711324
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Sui X, Hu Y, Ren C, Cao Q, Zhou S, Cao Y, Li M, Shu W, Huo R. METTL3-mediated m6A is required for murine oocyte maturation and maternal-to-zygotic transition. Cell Cycle. 2020 Jan 9:1-14. doi: 10.1080/15384101.2019.1711324. [Epub ahead of print].

ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane

Authors:
Jung E, Choi TI, Lee JE, Kim CH, Kim J
Citation:
FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29
Epub:
Not Epub
Abstract:
Proteins specialized in the detection, generation, or stabilization of membrane curvature play important roles in establishing...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1096/fj.201901778R
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung E, Choi TI, Lee JE, Kim CH, Kim J. ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane. FASEB J. 2020 Jan;34(1):1331-1344. doi: 10.1096/fj.201901778R. Epub 2019 Nov 29.

Programmed cell death along the midline axis patterns ipsilaterality in gastrulation

Authors:
Maya-Ramos L, Mikawa T
Citation:
Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731
Epub:
Not Epub
Abstract:
Bilateral symmetry is the predominant body plan in the animal kingdom. Cells on the left and right sides remain...
Link:
https://science.sciencemag.org/content/367/6474/197
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Maya-Ramos L, Mikawa T. Programmed cell death along the midline axis patterns ipsilaterality in gastrulation. Science. 2020;367(6474):197-200. doi:10.1126/science.aaw2731 .

NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis

Authors:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437
Epub:
Not Epub
Abstract:
Terminal selectors are transcription factors that control the morphological, physiological and molecular features that...
Link:
https://www.biorxiv.org/content/10.1101/2020.01.08.898437v1
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Tournière O, Dolan D, Richards GS, Sunagar K, Columbus-Shenkar YY, Moran Y, Rentzsch F. NvPOU4/Brain3 functions as a terminal selector gene in the nervous system of the cnidarian Nematostella vectensis. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.08.898437.

Dual role of Jam3b in early hematopoietic and vascular development

Authors:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M
Citation:
Development. 2020;147(1):dev181040. doi:10.1242/dev.181040
Epub:
Not Epub
Abstract:
In order to efficiently derive hematopoietic stem cells (HSCs) from pluripotent precursors, it is crucial to understand how...
Link:
https://dev.biologists.org/content/147/1/dev181040
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M. Dual role of Jam3b in early hematopoietic and vascular development. Development. 2020;147(1):dev181040. doi:10.1242/dev.181040 .

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