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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells

Authors:
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D
Citation:
Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5
Epub:
Yes
Abstract:
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual...
Link:
https://www.nature.com/articles/s41556-019-0330-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5.

Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression

Authors:
Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y
Citation:
Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7
Epub:
Not Epub
Abstract:
CUL4A and CUL4B are closely related members in Cullin family and can each assemble a Cullin-RING E3 ligase complex (Cullin-RING...
Link:
https://www.nature.com/articles/s41419-019-1629-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y. Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression. Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7.

CiliaCarta: An integrated and validated compendium of ciliary genes

Authors:
van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA
Citation:
PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705
Epub:
Not Epub
Abstract:
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216705
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA. CiliaCarta: An integrated and validated compendium of ciliary genes. PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705.

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

Authors:
Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M
Citation:
J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890
Epub:
Yes
Abstract:
About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia...
Link:
https://www.jci.org/articles/view/98890
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M. Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890.

Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes

Authors:
Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M
Citation:
Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12
Epub:
Not Epub
Abstract:
In vertebrates, the dorso-ventral (DV) axis is defined by the combinatorial action of localised Wnt, FGF and Nodal signalling...
Link:
https://www.sciencedirect.com/science/article/pii/S0925477312000251
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M. Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12.

Ninjurin1 regulates striated muscle growth and differentiation

Authors:
Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J
Citation:
PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987
Epub:
Not Epub
Abstract:
Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216987
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J. Ninjurin1 regulates striated muscle growth and differentiation. PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987.

MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

Authors:
Watterston C, Zeng L, Onabadejo A, Childs SJ
Citation:
PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print]
Epub:
Not Epub
Abstract:
As small regulatory transcripts, microRNAs (miRs) act as genetic 'fine tuners' of posttranscriptional events, and as...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008163
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Watterston C, Zeng L, Onabadejo A, Childs SJ. MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling. PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print].

A reference map of the human binary protein interactome

Authors:
Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, et al.
Citation:
Nature. 2020 Apr;580(7803):402-408. doi: 10.1038/s41586-020-2188-x. Epub 2020 Apr 8. PMID: 32296183; PMCID: PMC7169983
Epub:
Not Epub
Abstract:
Global insights into cellular organization and genome function require comprehensive understanding of the interactome networks...
Link:
https://www.nature.com/articles/s41586-020-2188-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, et al.. A reference map of the human binary protein interactome. Nature. 2020 Apr;580(7803):402-408. doi: 10.1038/s41586-020-2188-x. Epub 2020 Apr 8. PMID: 32296183; PMCID: PMC7169983.

Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry

Authors:
Lekk I, Duboc V, Faro A, Nicolaou S, Blader P, Wilson SW
Citation:
Elife. 2019 Aug 2;8:e47376. doi: 10.7554/eLife.47376. PMID: 31373552; PMCID: PMC6677535
Epub:
Not Epub
Abstract:
Left-right asymmetries in the zebrafish habenular nuclei are dependent upon the formation of the parapineal, a unilateral group...
Link:
https://elifesciences.org/articles/47376
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lekk I, Duboc V, Faro A, Nicolaou S, Blader P, Wilson SW. Sox1a mediates the ability of the parapineal to impart habenular left-right asymmetry. Elife. 2019 Aug 2;8:e47376. doi: 10.7554/eLife.47376. PMID: 31373552; PMCID: PMC6677535.

Identification of testicular cancer driver genes by a cross‐species comparative oncology approach

Authors:
Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF
Citation:
Andrology. 2019;[Epub ahead of print] doi:10.1111/andr.12644
Epub:
Yes
Abstract:
Background: Germ cell tumors arise in the testis, ovary, or extragonadal locations and have a wide range of histopathological...
Link:
https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12644
Organism or Cell Type:
zebrafish
Citation Extract:
Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF. Identification of testicular cancer driver genes by a cross‐species comparative oncology approach. Andrology. 2019;[Epub ahead of print] doi:10.1111/andr.12644.

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