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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Wnt11 regulates cardiac chamber development and disease during perinatal maturation
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Citation:
JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7 Epub:
Not Epub Abstract:
Ventricular chamber growth and development during perinatal circulatory transition is critical for functional adaptation of the... Delivery Method:
maternal i.v. for embryo delivery, Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Touma M, Kang X, Gao F, Zhao Y, Cass AA, Biniwale R, Xiao X, Eghbali M, Coppola G, Reemtsen B, Wang Y. Wnt11 regulates cardiac chamber development and disease during perinatal maturation. JCI Insight. 2017 Sep 7;2(17). pii: 94904. doi: 10.1172/jci.insight.94904. eCollection 2017 Sep 7. |
Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish
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Citation:
Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print] Epub:
Yes Abstract:
High throughput in vitro, in silico, and computational approaches have identified numerous environmental chemicals that... Organism or Cell Type:
zebrafish Citation Extract: Walter KM, Miller GW, Chen X, Harvey DJ, Puschner B, Lein PJ. Changes in Thyroid Hormone Activity Disrupt Photomotor Behavior of Larval Zebrafish. Neurotoxicology. 2019 May 20. pii: S0161-813X(19)30048-8. doi: 10.1016/j.neuro.2019.05.008. [Epub ahead of print]. |
AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo
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Citation:
ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print] Epub:
Yes Abstract:
Overexpression of bacterial efflux pumps are a driver of increasing antibiotic resistance in gram-negative pathogens. The AcrAB... Delivery Method:
peptide-linked Organism or Cell Type:
Enterobacteriaceae strains, Klebsiella pneumoniae, Pseudomonas aeruginosa Citation Extract: Sturge CR, Felder-Scott CF, Pifer R, Pybus C, Jain R, Geller B, Greenberg D. AcrAB-TolC Inhibition by Peptide-conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in vitro and in vivo. ACS Infect Dis. 2019 May 23. doi: 10.1021/acsinfecdis.9b00123. [Epub ahead of print]. |
EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo
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Citation:
Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051 Epub:
Yes Abstract:
Innate immunity is regulated by phagocytic cells and is critical for host control of bacterial infection. In many bacteria, the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q. EvpP inhibits neutrophils recruitment via Jnk-caspy inflammasome signaling in vivo. Fish & Shellfish Immunol. 2019;[Epub ahead of print] doi:10.1016/j.fsi.2019.05.051. |
Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish
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Citation:
Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print] Epub:
Yes Abstract:
Fertility and endocrine function rely on a tightly regulated synchronicity within the hypothalamic-pituitary gonadal (HPG) axis... Delivery Method:
microinjection Organism or Cell Type:
Oryzias latipes (medaka) Citation Extract: Guo H, Du X, Zhang Y, Wu J, Wang C, Li M, Hua X, Zhang XA, Yan J. Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal rejuvenation in zebrafish. Stem Cells. 2019 May 22. doi: 10.1002/stem.3040. [Epub ahead of print]. |
Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia
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Citation:
Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print] Epub:
Yes Abstract:
ABCD4, a member of the ATP-binding cassette transporter superfamily, is associated with the transport of vitamin B12 which is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Choi YM, Kim YI, Choi JH, Bhandari S, Nam IK, Hong K, Kwak S, So HS, Park DS, Kim CH, Choi TY, Choe SK. Loss of abcd4 in zebrafish leads to vitamin B12-deficiency anemia. Biochem Biophys Res Commun. 2019 May 18. pii: S0006-291X(19)30979-9. doi: 10.1016/j.bbrc.2019.05.099. [Epub ahead of print]. |
Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation
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Citation:
J Neurochem. 2018 Dec 17. doi: 10.1111/jnc.14645. [Epub ahead of print] Epub:
Yes Abstract:
MicroRNAs (miRNAs) released from the activated microglia upon neurotropic virus infection may exacerbate the neuronal damage.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice (brain) Citation Extract: Mukherjee S, Akbar I, Kumari B, Vrati S, Basu A, Banerjee A. Japanese Encephalitis Virus-induced let-7a/b interacted with the NOTCH-TLR7 pathway in microglia and facilitated neuronal death via caspase activation. J Neurochem. 2018 Dec 17. doi: 10.1111/jnc.14645. [Epub ahead of print]. |
Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis
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Citation:
Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5 Epub:
Not Epub Abstract:
Lymphatic endothelial cells arise from the venous endothelial cells in embryonic lymphatic development. However, the molecular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y. Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis. Sci Rep. 2019;9(1):7650 doi:10.1038/s41598-019-44095-5. |
Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse
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Citation:
Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497 Epub:
Not Epub Abstract:
Background: Mitral valve prolapse (MVP) is a common heart valve disease, the most frequent indication for valve repair or... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yu M, Georges A, Tucker NR, Kyryachenko S, Toomer K, Schott JJ, Delling FN, Fernandez-Friera L, Solis J, Ellinor PT, Levine RA, Slaugenhaupt SA, Hagège AA, Dina C, Jeunemaitre X, Milan DJ, Norris RA, Bouatia-Naji N. Genome-Wide Association Study-Driven Gene-Set Analyses, Genetic, and Functional Follow-Up Suggest GLIS1 as a Susceptibility Gene for Mitral Valve Prolapse. Circ Genom Precis Med. 2019 May;12(5):e002497. doi: 10.1161/CIRCGEN.119.002497. |
The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose
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Citation:
Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004 Epub:
Not Epub Abstract:
In this issue of Developmental Cell, Paraiso and colleagues report that antisense morpholino oligomers (MOs), frequently used... Organism or Cell Type:
Xenopus Citation Extract: Gentsch GE, Spruce T, Owens NDL, Monteiro RS, Smith JC. The Innate Immune Response of Frog Embryos to Antisense Morpholino Oligomers Depends on Developmental Stage, GC Content and Dose. Dev Cell. 2019;49(4):506-7. doi:10.1016/j.devcel.2019.05.004. |