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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Fluid dynamics during bleb formation in migrating cells in vivo

Authors:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E
Citation:
PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699
Epub:
Not Epub
Abstract:
Blebs are cellular protrusions observed in migrating cells and in cells undergoing spreading, cytokinesis, and apoptosis. Here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E. Fluid dynamics during bleb formation in migrating cells in vivo. PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699.

The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Authors:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M
Citation:
Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print]
Epub:
Yes
Abstract:
Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M. The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis. Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print].

ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth

Authors:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X
Citation:
Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761
Epub:
Not Epub
Abstract:
Human CLCN7 encodes voltage-gated chloride channel 7 (ClC-7); mutations of CLCN7 lead to osteopetrosis which is characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X. ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761.

Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE

Authors:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Citation:
Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2
Epub:
Not Epub
Abstract:
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells. Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE. Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2.

Microinjection methods for sea urchin eggs and blastomeres

Authors:
Yaguchi J
Citation:
Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28
Epub:
Not Epub
Abstract:
Methods for microinjection into sea urchin eggs have become relatively easier because of the technical improvements by a number...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus, Temnopleurus reevesii, Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Yaguchi J. Microinjection methods for sea urchin eggs and blastomeres. Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28.

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Authors:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW
Citation:
eLife. 2019;8:e40093 doi:10.7554/eLife.40093
Epub:
Not Epub
Abstract:
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW. Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLife. 2019;8:e40093 doi:10.7554/eLife.40093.

Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function

Authors:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA
Citation:
Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081.
Epub:
Not Epub
Abstract:
Joubert syndrome (JBTS) is an inherited autosomal recessive disorder associated with cerebellum and brainstem malformation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA. Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Front Cell Neurosci. 2019 Mar 21;13:81. doi: 10.3389/fncel.2019.00081. .

Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos

Authors:
Vázquez-Diez C, Paim LMG, FitzHarris G
Citation:
Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print]
Epub:
Yes
Abstract:
Chromosome segregation errors during mammalian preimplantation development cause "mosaic" embryos comprising a...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Vázquez-Diez C, Paim LMG, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print].

BMP signaling is required for amphioxus tail regeneration

Authors:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S
Citation:
Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print]
Epub:
Yes
Abstract:
Amphioxus, a cephalochordate, is an ideal animal in which to address questions about the evolution of regenerative ability and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Branchiostoma japonicum (amphioxus)
Citation Extract:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S. BMP signaling is required for amphioxus tail regeneration. Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print].

BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish

Authors:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q
Citation:
PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996
Epub:
Not Epub
Abstract:
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q. BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996.

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