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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis
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Citation:
Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019 Epub:
Not Epub Abstract:
It has recently been reported that a common side effect of translation-blocking morpholino antisense oligonucleotides is the... Organism or Cell Type:
Xenopus Citation Extract: Paraiso KD, Blitz IL, Zhou JJ, Cho KWY. Morpholinos Do Not Elicit an Innate Immune Response during Early Xenopus Embryogenesis. Dev Cell. 2019;49(4):643-50. doi:10.1016/j.devcel.2019.04.019. |
Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio)
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Citation:
Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1 Epub:
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Thyroid hormones (THs) are important regulators of gene expression during vertebrate development. In teleosts, early embryos... Organism or Cell Type:
zebrafish Citation Extract: Walpita CN, Crawford AD, Darras VM. Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio). Gen Comp Endocrinol. 2010 Mar 1;166(1):134-41. doi: 10.1016/j.ygcen.2009.09.011. Epub 2009 Oct 1. |
EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells
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Citation:
Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5 Epub:
Yes Abstract:
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a–Fzd9b signalling specificity in haematopoietic stem cells. Nat Cell Biol. 2019;[Ebut ahead of print] doi:10.1038/s41556-019-0330-5. |
Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression
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Citation:
Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7 Epub:
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CUL4A and CUL4B are closely related members in Cullin family and can each assemble a Cullin-RING E3 ligase complex (Cullin-RING... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y. Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression. Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7. |
CiliaCarta: An integrated and validated compendium of ciliary genes
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Citation:
PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705 Epub:
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The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA. CiliaCarta: An integrated and validated compendium of ciliary genes. PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705. |
Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis
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Citation:
J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890 Epub:
Yes Abstract:
About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M. Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890. |
Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes
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Citation:
Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12 Epub:
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In vertebrates, the dorso-ventral (DV) axis is defined by the combinatorial action of localised Wnt, FGF and Nodal signalling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M. Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12. |
Ninjurin1 regulates striated muscle growth and differentiation
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Citation:
PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987 Epub:
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Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J. Ninjurin1 regulates striated muscle growth and differentiation. PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987. |
MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling
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Citation:
PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print] Epub:
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As small regulatory transcripts, microRNAs (miRs) act as genetic 'fine tuners' of posttranscriptional events, and as... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Watterston C, Zeng L, Onabadejo A, Childs SJ. MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling. PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print]. |
Quantitative measurements of chromatin modification dynamics during zygotic genome activation
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Citation:
bioRxiv. 2019;[preprint] doi:10.1101/601393 Epub:
Not Epub Abstract:
Histone posttranslational modifications (PTMs) are key gene expression regulators, but their rapid dynamics during development... Organism or Cell Type:
zebrafish Citation Extract: Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew T-L, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Hiroshi Kimura H. Quantitative measurements of chromatin modification dynamics during zygotic genome activation. bioRxiv. 2019;[preprint] doi:10.1101/601393. |