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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane

Authors:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y
Citation:
Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008
Epub:
Yes
Abstract:
A new nanopore array/Au electrode was fabricated and applied to the detection of microRNA. The electrode was prepared via...
Citation Extract:
Li C, He L, Jiang S, Mo R, Yan X, Qian Z-J, Zhou C, Sun S, Hong P, Huang Y. Ultrasensitive detection of microRNA using an array of Au nanowires deposited within the channels of a porous anodized alumina membrane. Elecrochem Comm. 2019;[Epub ahead of print] doi:10.1016/j.elecom.2019.03.008.

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly

Authors:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A
Citation:
Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w
Epub:
Not Epub
Abstract:
A failure in optic fissure fusion during development can lead to blinding malformations of the eye. Here, we report a syndrome...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lahrouchi N, George A, Ratbi I, Schneider R, Elalaoui SC, Moosa S, Bharti S, Sharma R, Abu-Asab M, Onojafe F, Adadi N, Lodder EM, Laarabi F-Z, Lamsyah Y, Elorch H, Chebbar I, Postma AV, Lougaris V, Plebani A, Altmueller J, Kyrieleis H, Meiner V, McNeill H, Bharti K, Lyonnet S, Wollnik B, Henrion-Caude A, Berraho A, Hildebrandt F, Bezzina CR, Brooks BP, Sefiani A. Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. Nat Comm. 2019;10:1180. doi:10.1038/s41467-019-08547-w.

Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer

Authors:
Umali J, Hawkey-Noble A, French CR
Citation:
Vision Res. 2019 Mar;156:66-72. doi: 10.1016/j.visres.2019.01.008. Epub 2019 Feb 2
Epub:
Not Epub
Abstract:
Mutation of FOXC1 causes Axenfeld-Rieger Syndrome (ARS) with early onset or congenital glaucoma. We assessed retinal ganglion...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Umali J, Hawkey-Noble A, French CR. Loss of foxc1 in zebrafish reduces optic nerve size and cell number in the retinal ganglion cell layer. Vision Res. 2019 Mar;156:66-72. doi: 10.1016/j.visres.2019.01.008. Epub 2019 Feb 2.

Proteasomal inhibition attenuates craniofacial malformations in a zebrafish model of Treacher Collins Syndrome

Authors:
Rosas MG, Lorenzatti A, de Peralta MSP, Calcatera NB, Coux G
Citation:
Biochem Pharmacol. 2019 Mar 5. pii: S0006-2952(19)30091-7. doi: 10.1016/j.bcp.2019.03.005. [Epub ahead of print]
Epub:
Yes
Abstract:
Treacher Collins Syndrome (TCS) is a congenital disease characterized by defects in the craniofacial skeleton and absence of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosas MG, Lorenzatti A, de Peralta MSP, Calcatera NB, Coux G. Proteasomal inhibition attenuates craniofacial malformations in a zebrafish model of Treacher Collins Syndrome. Biochem Pharmacol. 2019 Mar 5. pii: S0006-2952(19)30091-7. doi: 10.1016/j.bcp.2019.03.005. [Epub ahead of print].

Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride

Authors:
Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y
Citation:
Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a severe muscle disorder characterised by mutations in the DMD gene. Recently, we have...
Delivery Method:
Endo-Porter
Organism or Cell Type:
human MYOD1-urine-derived cells and MYOD1-converted fibroblasts
Citation Extract:
Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y. Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride. Sci Rep. 2019;9(1):3807. doi:10.1038/s41598-019-40421-z.

bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish

Authors:
Ghersi JJ, Mahony CB, Bertrand JY
Citation:
Development. 2019;dev.164103. doi:10.1242/dev.164103
Epub:
Not Epub
Abstract:
Hematopoiesis maintains the entire blood system and dysregulation of this process can lead to malignancies (leukemia),...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ghersi JJ, Mahony CB, Bertrand JY. bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development. 2019;dev.164103. doi:10.1242/dev.164103.

Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos

Authors:
Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C
Citation:
Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y
Epub:
Not Epub
Abstract:
VEGFA signaling controls physiological and pathological angiogenesis and hematopoiesis. Although many context-dependent...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li L, Rispoli R, Patient R, Ciau-Uitz A, Porcher C. Etv6 activates vegfa expression through positive and negative transcriptional regulatory networks in Xenopus embryos. Nat Commun. 2019 Mar 6;10(1):1083. doi: 10.1038/s41467-019-09050-y.

L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing

Authors:
Linneberg C, Toft CLF, Kjaer-Sorensen K, Laursen LS
Citation:
Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x
Epub:
Not Epub
Abstract:
Normal brain development depends on tight temporal and spatial regulation of connections between cells. Mutations in L1cam, a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Linneberg C, Toft CLF, Kjaer-Sorensen K, Laursen LS. L1cam-mediated developmental processes of the nervous system are differentially regulated by proteolytic processing. Sci Rep. 2019 Mar 6;9(1):3716. doi: 10.1038/s41598-019-39884-x.

Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation

Authors:
Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ
Citation:
Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1
Epub:
Not Epub
Abstract:
The mechanisms underlying zebrafish pancreatic islet vascularization have not been well characterized. We sought to determine...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Toselli CM, Wilkinson BM, Paterson J, Kieffer TJ. Vegfa/vegfr2 signaling is necessary for zebrafish islet vessel development, but is dispensable for beta-cell and alpha-cell formation. Sci Rep. 2019 Mar 5;9(1):3594. doi: 10.1038/s41598-019-40136-1.

Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1

Authors:
Poganik JR, Long MJC, Disare MT, Liu X, Chang S-H, Hla T, Aye Y
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/565937
Epub:
Not Epub
Abstract:
The Nrf2-driven antioxidant response (AR) is a target of covalent drugs and bioactive native electrophiles. However, much of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Poganik JR, Long MJC, Disare MT, Liu X, Chang S-H, Hla T, Aye Y. Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1. bioRxiv. 2019;[preprint] doi:10.1101/565937.

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