You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia

Authors:
Kim J, Park EA, Shin MY, Park SJ
Citation:
Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print
Epub:
Not Epub
Abstract:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that control the eukaryotic cell cycle. Limited information is...
Link:
https://journals.asm.org/doi/10.1128/spectrum.04919-22
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Kim J, Park EA, Shin MY, Park SJ. Functional Differentiation of Cyclins and Cyclin-Dependent Kinases in Giardia lamblia. Microbiol Spectr. 2023 Mar 6:e0491922. doi: 10.1128/spectrum.04919-22. Online ahead of print.

YULINK regulates vascular formation in zebrafish and HUVECs

Authors:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J
Citation:
Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8
Epub:
Not Epub
Abstract:
Background: The distinct arterial and venous cell fates are dictated by a combination of various genetic factors which form...
Link:
https://biolres.biomedcentral.com/articles/10.1186/s40659-023-00415-8
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin HH, Kuo MW, Fan TC, Yu AL, Yu J. YULINK regulates vascular formation in zebrafish and HUVECs. Biol Res. 2023;56(7). doi:10.1186/s40659-023-00415-8.

In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery

Authors:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL
Citation:
ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print
Epub:
Yes
Abstract:
Peptide-mediated delivery of macromolecules in cells has significant potential therapeutic benefits, but no therapy employing...
Link:
https://pubs.acs.org/doi/10.1021/acschembio.2c00920
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Schissel CK, Farquhar CE, Loas A, Malmberg AB, Pentelute BL. In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery. ACS Chem Biol. 2023 Mar 1. doi: 10.1021/acschembio.2c00920. Online ahead of print.

Mob4 is required for neurodevelopment in zebrafish

Authors:
Florindo C, Mimoso JM, Palma SL, Gonçalves C, Silvestre D, Campinho M, Tavares A
Citation:
microPublication Biology. 2023. 10.17912/micropub.biology.000762
Epub:
Not Epub
Abstract:
Mob4 is an essential evolutionary conserved protein shown to play roles in cell division and neural development. Mob4 is a core...
Link:
https://www.micropublication.org/journals/biology/micropub-biology-000762
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Florindo C, Mimoso JM, Palma SL, Gonçalves C, Silvestre D, Campinho M, Tavares A. Mob4 is required for neurodevelopment in zebrafish. microPublication Biology. 2023. 10.17912/micropub.biology.000762.

U1 AMO (antisense morpholino oligo) disrupts U1 snRNP structure to promote intronic premature cleavage and polyadenylation (PCPA)

Authors:
Feng Q, Lin Z, Deng Y, Ran Y, Xiang AP, Ye C, Yao C
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.24.529985
Epub:
Not Epub
Abstract:
Functional depletion of U1 snRNP with a 25 nt U1 AMO (antisense morpholino oligonucleotides) may lead to intronic premature...
Link:
https://www.biorxiv.org/content/10.1101/2023.02.24.529985v1
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Feng Q, Lin Z, Deng Y, Ran Y, Xiang AP, Ye C, Yao C. U1 AMO (antisense morpholino oligo) disrupts U1 snRNP structure to promote intronic premature cleavage and polyadenylation (PCPA). bioRxiv. 2023;[preprint] doi:10.1101/2023.02.24.529985.

Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish

Authors:
Khatri D, Putoux A, Cologne A, Kaltenbach S, Besson A, Bertiaux E, Guguin J, Fendler A, Dupont MA, Benoit-Pilven C, Qebibo L, Ahmed-Elie S, Audebert-Bellanger S, Blanc P, Rambaud T, Castelle M, Cornen G, Grotto S, Guët A, Guibaud L, Michot C, Odent S, Ruaud L, Sacaze E, Hamel V, Bordonné R, Leutenegger AL, Edery P, Burglen L, Attié-Bitach T, Mazoyer S, Delous M
Citation:
Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21
Epub:
Not Epub
Abstract:
In the human genome, about 750 genes contain one intron excised by the minor spliceosome. This spliceosome comprises its own...
Link:
https://www.pnas.org/doi/10.1073/pnas.2102569120
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Khatri D, Putoux A, Cologne A, Kaltenbach S, Besson A, Bertiaux E, Guguin J, Fendler A, Dupont MA, Benoit-Pilven C, Qebibo L, Ahmed-Elie S, Audebert-Bellanger S, Blanc P, Rambaud T, Castelle M, Cornen G, Grotto S, Guët A, Guibaud L, Michot C, Odent S, Ruaud L, Sacaze E, Hamel V, Bordonné R, Leutenegger AL, Edery P, Burglen L, Attié-Bitach T, Mazoyer S, Delous M. Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2102569120. doi: 10.1073/pnas.2102569120. Epub 2023 Feb 21.

Quantifying endothelial cell proliferation in the zebrafish embryo

Authors:
Bowley G, Chico TJ, Serbanovic-Canic J, Evans PC
Citation:
F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021
Epub:
Not Epub
Abstract:
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and...
Link:
https://f1000research.com/articles/10-1032/v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bowley G, Chico TJ, Serbanovic-Canic J, Evans PC. Quantifying endothelial cell proliferation in the zebrafish embryo. F1000Res. 2021 Oct 11;10:1032. doi: 10.12688/f1000research.73130.1. eCollection 2021.

Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

Authors:
Ang Z, Hayer KE, Diz MT, Schmidt C, Zheng S, Xu F, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Schuster SJ, Thomas-Tikhonenko A
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123
Epub:
Not Epub
Abstract:
CD20-directed immunotherapies, such as rituximab, are mainstays of clinical management of mature B-cell neoplasms, previously...
Link:
https://www.biorxiv.org/content/10.1101/2023.02.19.529123v1
Delivery Method:
electroporation of standard Morpholino; Vivo-Morpholino
Organism or Cell Type:
cell culture: OCI-Ly8, Raji and MEC-1
Citation Extract:
Ang Z, Hayer KE, Diz MT, Schmidt C, Zheng S, Xu F, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Schuster SJ, Thomas-Tikhonenko A. Alternative splicing of its 5' untranslated region controls CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123.

Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney

Authors:
Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA
Citation:
Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666
Epub:
Not Epub
Abstract:
Despite significant advances in understanding nephron segment patterning, many questions remain about the underlying genes and...
Link:
https://www.mdpi.com/2073-4409/12/4/666
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wesselman HM, Gatz AE, Pfaff MR, Arceri L, Wingert RA. Estrogen Signaling Influences Nephron Segmentation of the Zebrafish Embryonic Kidney. Cells. 2023 Feb 20;12(4):666. doi:10.3390/cells12040666.

USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling

Authors:
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E
Citation:
Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7
Epub:
Not Epub
Abstract:
The Wnt-β-catenin signal transduction pathway is essential for embryonic development and adult tissue homeostasis. Wnt...
Link:
https://www.science.org/doi/10.1126/scisignal.abn8372
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7.

Pages