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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity

Authors:
Xia J, Liu M, Zhu C, Liu S, Ai L, Ma D, Zhu P, Wang L, Liu F
Citation:
Cell Res. 2023 Apr 4. doi: 10.1038/s41422-023-00797-0. Online ahead of print
Epub:
Yes
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are considered as a heterogeneous population, but precisely when, where and how...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia J, Liu M, Zhu C, Liu S, Ai L, Ma D, Zhu P, Wang L, Liu F. Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity. Cell Res. 2023 Apr 4. doi: 10.1038/s41422-023-00797-0. Online ahead of print.

Characterization of regeneration initiating cells during Xenopus laevis tail regeneration

Authors:
Radek S, Pavel A, Daniel Z, Ravindra N, Daniel K, Jiri N, Karel Jr. S, Lacina L, Beduya EB, Jiri N, Martin P, Mikael K
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.30.534908
Epub:
Not Epub
Abstract:
Embryos are regeneration and wound healing masters. They not only rapidly close their wounds, remodel injured tissue without a...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Radek S, Pavel A, Daniel Z, Ravindra N, Daniel K, Jiri N, Karel Jr. S, Lacina L, Beduya EB, Jiri N, Martin P, Mikael K. Characterization of regeneration initiating cells during Xenopus laevis tail regeneration. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.30.534908 .

Colec12 and Trail signaling confine cranial neural crest cell trajectories and promote collective cell migration

Authors:
McLennan R, Giniunaite R, Hildebrand K, Teddy JM, Kasemeier-Kulesa JC, Bolanos L, Baker RE, Maini PK, Kulesa PM
Citation:
Dev Dyn. 2023 Jan 24. doi:10.1002/dvdy.569. Online ahead of print
Epub:
Yes
Abstract:
Background: Collective and discrete neural crest cell (NCC) migratory streams are crucial to vertebrate head patterning....
Delivery Method:
microinjection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, Giniunaite R, Hildebrand K, Teddy JM, Kasemeier-Kulesa JC, Bolanos L, Baker RE, Maini PK, Kulesa PM. Colec12 and Trail signaling confine cranial neural crest cell trajectories and promote collective cell migration. Dev Dyn. 2023 Jan 24. doi:10.1002/dvdy.569. Online ahead of print.

Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation

Authors:
Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z
Citation:
J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print
Epub:
Not Epub
Abstract:
Background: Although retinitis pigmentosa (RP) is the most common type of hereditary retinal dystrophy, approximately 25%-45%...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z. Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation. J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print.

Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling

Authors:
Liang F, Lu X, Wu B, Yang Y, Qin W
Citation:
Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538
Epub:
Not Epub
Abstract:
Ribosomes are the vital molecular machine for protein translation in a cell. Defects in several nucleolar proteins have been...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liang F, Lu X, Wu B, Yang Y, Qin W. Nucleolar Protein 56 Deficiency in Zebrafish Leads to Developmental Abnormalities and Anemia via p53 and JAK2-STAT3 Signaling. Biology. 2023; 12(4):538. https://doi.org/10.3390/biology12040538.

Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length

Authors:
Tang L, Qiu W, Zhang S, Wang J, Yang X, Xu B, Magnuson JT, Xu EG, Wu M, Zheng C
Citation:
Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print
Epub:
Not Epub
Abstract:
Previous studies have reported the immunotoxicity of per- and polyfluoroalkyl substances (PFASs), but it remains a significant...
Organism or Cell Type:
zebrafish
Citation Extract:
Tang L, Qiu W, Zhang S, Wang J, Yang X, Xu B, Magnuson JT, Xu EG, Wu M, Zheng C. Poly- and Perfluoroalkyl Substances Induce Immunotoxicity via the TLR Pathway in Zebrafish: Links to Carbon Chain Length. Environ Sci Technol. 2023;57(15): 6139–49. doi:10.1021/acs.est.2c09716. Online ahead of print.

BDNF signaling in correlation-dependent structural plasticity in the developing visual system

Authors:
Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES
Citation:
PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070
Epub:
Not Epub
Abstract:
During development, patterned neural activity instructs topographic map refinement. Axons with similar patterns of neural...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kutsarova E, Schohl A, Munz M, Wang A, Zhang YY, Bilash OM, Ruthazer ES. BDNF signaling in correlation-dependent structural plasticity in the developing visual system. PLoS Biol. 2023;21(4):e3002070. doi:10.1371/journal.pbio.3002070.

Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis

Authors:
Montealegre S, de Calbiac H, Straube M, Debruge H, Chentout L, Ciura S, Imbard A, Le Guillou E, Marian A, Goudin N, Caccavelli L, Fabrega S, Hubas A, van Endert P, Dupont N, Diana J, Kabashi E, de Lonlay P
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.29.534583
Epub:
Not Epub
Abstract:
Patients with pathogenic variants in the TANGO2 gene suffer from severe and recurrent rhabdomyolysis (RM) episodes precipitated...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montealegre S, de Calbiac H, Straube M, Debruge H, Chentout L, Ciura S, Imbard A, Le Guillou E, Marian A, Goudin N, Caccavelli L, Fabrega S, Hubas A, van Endert P, Dupont N, Diana J, Kabashi E, de Lonlay P. Abnormal autophagy is a critical mechanism in TANGO2-related rhabdomyolysis. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.29.534583.

Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation

Authors:
Buglak DB, Bougaran P, Kulikauskas MR, Liu Z, Monaghan-Benson E, Gold AL, Marvin AP, Burciu A, Tanke NT, Oatley M, Ricketts SN, Kinghorn K, Johnson BN, Shiau CE, Rogers S, Guilluy C, Bautch VL
Citation:
eLife. 2023;12:e83652. doi:10.7554/eLife.83652
Epub:
Not Epub
Abstract:
Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Buglak DB, Bougaran P, Kulikauskas MR, Liu Z, Monaghan-Benson E, Gold AL, Marvin AP, Burciu A, Tanke NT, Oatley M, Ricketts SN, Kinghorn K, Johnson BN, Shiau CE, Rogers S, Guilluy C, Bautch VL. Nuclear SUN1 stabilizes endothelial cell junctions via microtubules to regulate blood vessel formation. eLife. 2023;12:e83652. doi:10.7554/eLife.83652.

Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture

Authors:
Prescott M, Moulton H, Pastey M
Citation:
SSRN. 2022:[preprint] doi:10.2139/ssrn.4057449
Epub:
Not Epub
Abstract:
Influenza is a global health issue causing substantial health and economic burdens in affected populations. Routine, annual...
Citation Extract:
Prescott M, Moulton H, Pastey M. Inhibition of Interferon Alpha by a Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer Increases Influenza Virus Replication in Chicken Embryo Fibroblast (DF-1) Cells; An Alternative Strategy to Increasing Vaccine Production in Cell Culture. SSRN. 2022:[preprint] doi:10.2139/ssrn.4057449.

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