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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
N-Fluoroalkylated Morpholinos - a New Class of Nucleoside Analogues
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Citation:
Chemistry. 2022 Nov 27. doi: 10.1002/chem.202203248. Online ahead of print. PMID: 36437234 Epub:
Not Epub Abstract:
The first concise and efficient synthesis of some fluorine-containing morpholino nucleosides analogs has been developed. One... Citation Extract: Debreczeni N, Hotzi J, Bege M, Lovas M, Mező E, Bereczki I, Herczegh P, Kiss L, Borbás A. N-Fluoroalkylated Morpholinos - a New Class of Nucleoside Analogues. Chemistry. 2022 Nov 27. doi: 10.1002/chem.202203248. Online ahead of print. PMID: 36437234 . |
Use of vivo-morpholinos for gene knockdown in the postnatal shark retina
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Citation:
Exp Eye Res. 2022 Nov 24:109333. doi: 10.1016/j.exer.2022.109333. Online ahead of print Epub:
Yes Abstract:
Work in the catshark Scyliorhinus canicula has shown that the evolutionary origin of postnatal neurogenesis in vertebrates is... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Scyliorhinus canicula (catshark) Citation Extract: Rodríguez-Arrizabalaga M, Hernández-Núñez I, Candal E, Barreiro-Iglesias A. Use of vivo-morpholinos for gene knockdown in the postnatal shark retina. Exp Eye Res. 2022 Nov 24:109333. doi: 10.1016/j.exer.2022.109333. Online ahead of print. |
Loss of Apical Sodium Bile Acid Transporter Disrupts Bile Acid Circulation and Reduces Biliary Damage in Cholangitis
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Citation:
Am J Physiol Gastrointest Liver Physiol. 2022 Nov 21. doi: 10.1152/ajpgi.00112.2022. Online ahead of print Epub:
Yes Abstract:
Background: Primary Sclerosing Cholangitis (PSC) is characterized by increased ductular reaction (DR), liver fibrosis, hepatic... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Meadows V, Marakovits C, Ekser B, Kundu D, Zhou T, Kyritsi K, Pham L, Chen L, Kennedy L, Ceci L, Wu N, Carpino G, Zhang W, Isidan A, Meyer A, Owen T, Gaudio E, Onori P, Alpini GD, Francis H. Loss of Apical Sodium Bile Acid Transporter Disrupts Bile Acid Circulation and Reduces Biliary Damage in Cholangitis. Am J Physiol Gastrointest Liver Physiol. 2022 Nov 21. doi: 10.1152/ajpgi.00112.2022. Online ahead of print. |
Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP
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Citation:
Nucleic Acids Res. 2022 Nov 18:gkac1054. doi: 10.1093/nar/gkac1054. Online ahead of print Epub:
Yes Abstract:
The enteroviral 2C protein is a therapeutic target, but the absence of a mechanistic framework for this enzyme limits our... Citation Extract: Yeager C, Carter G, Gohara DW, Yennawar NH, Enemark EJ, Arnold JJ, Cameron CE. Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP. Nucleic Acids Res. 2022 Nov 18:gkac1054. doi: 10.1093/nar/gkac1054. Online ahead of print. |
Hnf1b renal expression directed by a distal enhancer responsive to Pax8
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Citation:
Sci Rep. 2022 Nov 19;12(1):19921. doi: 10.1038/s41598-022-21171-x Epub:
Not Epub Abstract:
Xenopus provides a simple and efficient model system to study nephrogenesis and explore the mechanisms causing renal... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Goea L, Buisson I, Bello V, Eschstruth A, Paces-Fessy M, Le Bouffant R, Chesneau A, Cereghini S, Riou JF, Umbhauer M. Hnf1b renal expression directed by a distal enhancer responsive to Pax8. Sci Rep. 2022 Nov 19;12(1):19921. doi: 10.1038/s41598-022-21171-x. |
Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells
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Citation:
EMBO Rep. 2022 Nov 21:e54984. doi: 10.15252/embr.202254984. Online ahead of print Epub:
Not Epub Abstract:
Spinal cord injury (SCI) can cause long-lasting disability in mammals due to the lack of axonal regrowth together with the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Zhu P, Zheng P, Kong X, Wang S, Cao M, Zhao C. Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells. EMBO Rep. 2022 Nov 21:e54984. doi: 10.15252/embr.202254984. Online ahead of print. |
The effect and underlying mechanism of yeast β-glucan on antiviral resistance of zebrafish against spring viremia of carp virus infection
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Citation:
Front Immunol. 2022 Nov 3;13:1031962. doi: 10.3389/fimmu.2022.1031962. eCollection 2022 Epub:
Not Epub Abstract:
β-glucan has been used as immunostimulant for fish. However, the effect of yeast β-glucan on viral infections has been less... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
zebrafish Citation Extract: Liang H, Li Y, Li M, Zhou W, Chen J, Zhang Z, Yang Y, Ran C, Zhou Z. The effect and underlying mechanism of yeast β-glucan on antiviral resistance of zebrafish against spring viremia of carp virus infection. Front Immunol. 2022 Nov 3;13:1031962. doi: 10.3389/fimmu.2022.1031962. eCollection 2022. |
Developing Therapeutic Splice-Correcting Antisense Oligomers for Adult-Onset Pompe Disease with c.-32-13T>G Mutation
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Citation:
Methods Mol Biol. 2023;2587:239-251. doi: 10.1007/978-1-0716-2772-3_14 Epub:
Not Epub Abstract:
The mutation c.-32-13T>G in the GAA gene impacts normal exon 2 splicing and is found in two-thirds of late-onset Pompe... Organism or Cell Type:
cell culture: fibroblast, forced-myogenic cells Citation Extract: Ham KA, Johnsen RD, Tchan M, Wilton SD, Aung-Htut MT. Developing Therapeutic Splice-Correcting Antisense Oligomers for Adult-Onset Pompe Disease with c.-32-13T>G Mutation. Methods Mol Biol. 2023;2587:239-251. doi: 10.1007/978-1-0716-2772-3_14. |
Peptide-Conjugated PMOs for the Treatment of Myotonic Dystrophy
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Citation:
Methods Mol Biol. 2023;2587:209-237. doi: 10.1007/978-1-0716-2772-3_13 Epub:
Not Epub Abstract:
Antisense oligonucleotides (ASOs) have shown great therapeutic potential in the treatment of many neuromuscular diseases... Delivery Method:
peptide-linked Organism or Cell Type:
mice Citation Extract: Stoodley J, Miraz DS, Jad Y, Fischer M, Wood MJA, Varela MA. Peptide-Conjugated PMOs for the Treatment of Myotonic Dystrophy. Methods Mol Biol. 2023;2587:209-237. doi: 10.1007/978-1-0716-2772-3_13. |
Morpholino-Mediated Exons 28-29 Skipping of Dysferlin and Characterization of Multiexon-skipped Dysferlin using RT-PCR
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Citation:
Immunoblotting, and Membrane Wounding Assay. Methods Mol Biol. 2023;2587:183-196. doi: 10.1007/978-1-0716-2772-3_11 Epub:
Not Epub Abstract:
Dysferlinopathies are a group of disabling muscular dystrophies that includes limb girdle muscular dystrophy type 2B (LGMD2B),... Citation Extract: Anwar S, Yokota T. Morpholino-Mediated Exons 28-29 Skipping of Dysferlin and Characterization of Multiexon-skipped Dysferlin using RT-PCR. Immunoblotting, and Membrane Wounding Assay. Methods Mol Biol. 2023;2587:183-196. doi: 10.1007/978-1-0716-2772-3_11. |