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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Investigating the Impact of Delivery Routes for Exon Skipping Therapies in the CNS of DMD Mouse Models
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Citation:
Cells. 2023;12(6):908. doi:10.3390/cells12060908 Epub:
Not Epub Abstract:
Nucleic acid-based therapies have demonstrated great potential for the treatment of monogenetic diseases, including neurologic... Delivery Method:
intraperitoneal (ip), intracerebroventricular (icv), intra-cisterna magna (icm), osmotic pump Organism or Cell Type:
mice Citation Extract: Saoudi A, Fergus C, Gileadi T, Montanaro F, Morgan JE, Kelly VP, Tensorer T, Garcia L, Vaillend C, Muntoni F, Goyenvalle A. Investigating the Impact of Delivery Routes for Exon Skipping Therapies in the CNS of DMD Mouse Models. Cells. 2023;12(6):908. doi:10.3390/cells12060908. |
Genetic mapping and molecular mechanism behind color variation in the Asian vine snake
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Citation:
Genome Biol. 2023 Mar 9;24(1):46. doi: 10.1186/s13059-023-02887-z Epub:
Not Epub Abstract:
Background: Reptiles exhibit a wide variety of skin colors, which serve essential roles in survival and reproduction. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Tang CY, Zhang X, Xu X, Sun S, Peng C, Song MH, Yan C, Sun H, Liu M, Xie L, Luo SJ, Li JT. Genetic mapping and molecular mechanism behind color variation in the Asian vine snake. Genome Biol. 2023 Mar 9;24(1):46. doi: 10.1186/s13059-023-02887-z. |
Diflovidazin damages the hematopoietic stem cells to zebrafish embryos via the TLR4/ NF-κB/ p53 pathway
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Citation:
Fish Shellfish Immunol. 2023 Mar 7:108672. doi: 10.1016/j.fsi.2023.108672. Online ahead of print Epub:
Yes Abstract:
Exposure to environmental contaminants frequently induces the occurrence of blood diseases, but the underlying molecular... Organism or Cell Type:
zebrafish Citation Extract: Jia K, Xiong H, Yuan W, Huang L, Xu J, Lu C, Hu Y, Huang K, Luo Q, Ma J, Lu H. Diflovidazin damages the hematopoietic stem cells to zebrafish embryos via the TLR4/ NF-κB/ p53 pathway. Fish Shellfish Immunol. 2023 Mar 7:108672. doi: 10.1016/j.fsi.2023.108672. Online ahead of print. |
Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP
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Citation:
Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073 Epub:
Not Epub Abstract:
In order to report clinically actionable incidental findings in genetic testing, the American College of Medical Genetics and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Elfatih A, Da'as SI, Abdelrahman D, Mbarek H, Mohammed I, Hasan W, Fakhro KA; The Qatar Genome Program Research Consortium; Estivill X, Mifsud B. Analysis of incidental findings in Qatar genome participants reveals novel functional variants in LMNA and DSP. Hum Mol Genet. 2022 Aug 23;31(16):2796-2809. doi: 10.1093/hmg/ddac073. |
Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin
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Citation:
J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546 Epub:
Not Epub Abstract:
Current therapies have limited treatment effect on cancer. Combinational delivery of multiple therapeutics has been commonly... Delivery Method:
nanoparticle Organism or Cell Type:
cell culture: breast cancer Citation Extract: Tunc CU, Culha M. Gold nanoparticles conjugated DNA-tile nanomaterials for simultaneous delivery of morpholino antisense oligonucleotides and doxorubicin. J Drug Deliv Sci Technol. 2022;74:103546. doi:10.1016/j.jddst.2022.103546. |
Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance
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Citation:
Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5 Epub:
Not Epub Abstract:
The nucleolus is the most prominent membraneless condensate in the nucleus. It comprises hundreds of proteins with distinct... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shan L, Xu G, Yao R-W, Luan P-F, Huang Y, Zhang P-H, Pan Y-H, Zhang L, Gao X, Li Y, Cao S-M, Gao S-X, Yang Z-H, Li S, Yang L-Z, Wang Y, Wong CCL, Yu L, Li J, Yang L, Chen L-L. Nucleolar URB1 ensures 3′ ETS rRNA removal to prevent exosome surveillance. Nature. 2023;[Epub ahead of orint]. doi:10.1038/s41586-023-05767-5. |
Mucociliary Wnt signaling promotes cilia biogenesis and beating
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Citation:
Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2 Epub:
Not Epub Abstract:
It is widely thought that Wnt/Lrp6 signaling proceeds through the cytoplasm and that motile cilia are signaling-inert... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Mucociliary Wnt signaling promotes cilia biogenesis and beating. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2. |
Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis
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Citation:
Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y Epub:
Not Epub Abstract:
Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Murayama E, Vivier C, Schmidt A, Herbomel P. Alcam-a and Pdgfr-α are essential for the development of sclerotome-derived stromal cells that support hematopoiesis. Nat Commun. 2023 Mar 1;14(1):1171. doi: 10.1038/s41467-023-36612-y. |
Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.28.530560 Epub:
Not Epub Abstract:
Vertebrate pigmentation is an outcome of an interplay of several signaling pathways that result in immense diversity of pigment... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Subramaniam Y, Sharma B, Aggarwal A, Raja DA, Gupta I, Ghazi M, Sivasubbu S, Natarajan VT. Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.28.530560 . |
Temporal single-cell transcriptomic analysis of the sox1a:eGFP transgenic line identified the lateral floor plate progenitor cells as the origin of intraspinal serotonergic neurons
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.01.530240 Epub:
Not Epub Abstract:
The Sox family of transcription factors plays a crucial role in the development of the vertebrate nervous system. In the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen F, Köhler M, Cucun G, Takamiya M, Kizil C, Cosacak MI, Rastegar S. Temporal single-cell transcriptomic analysis of the sox1a:eGFP transgenic line identified the lateral floor plate progenitor cells as the origin of intraspinal serotonergic neurons. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.01.530240. |