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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Acupuncture Needle-Based Transistor Neuroprobe for In Vivo Monitoring of Neurotransmitter

Authors:
Zhou Y, Liu B, Lei Y, Tang L, Li T, Yu S, Zhang GJ, Li YT
Citation:
Small. 2022 Nov 7:e2204142. doi: 10.1002/smll.202204142. Online ahead of print
Epub:
Not Epub
Abstract:
Nevertheless, in vivo real-time monitoring of neurotransmitters released in the brain, especially the electrochemically...
Organism or Cell Type:
rat
Citation Extract:
Zhou Y, Liu B, Lei Y, Tang L, Li T, Yu S, Zhang GJ, Li YT. Acupuncture Needle-Based Transistor Neuroprobe for In Vivo Monitoring of Neurotransmitter. Small. 2022 Nov 7:e2204142. doi: 10.1002/smll.202204142. Online ahead of print.

osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2

Authors:
Drummond BE, Chambers BE, Wesselman HM, Gibson S, Arceri L, Ulrich MN, Gerlach GF, Kroeger PT, Leshchiner I, Goessling W, Wingert RA
Citation:
Biomedicines. 2022;10(11):2868. doi:10.3390/biomedicines10112868
Epub:
Not Epub
Abstract:
Knowledge about the genetic pathways that control nephron development is essential for better understanding the basis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Drummond BE, Chambers BE, Wesselman HM, Gibson S, Arceri L, Ulrich MN, Gerlach GF, Kroeger PT, Leshchiner I, Goessling W, Wingert RA. osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2. Biomedicines. 2022;10(11):2868. doi:10.3390/biomedicines10112868.

Antibody-oligonucleotide conjugate achieves central nervous system delivery in animal models for spinal muscular atrophy

Authors:
Hammond SM, Abendroth F, Goli L, Stoodley J, Burrell M, Thom G, Gurrell I, Ahlskog N, Gait MJ, Wood MJ, Webster CI
Citation:
JCI Insight. 2022 Nov 8:e154142. doi: 10.1172/jci.insight.154142. Online ahead of print
Epub:
Yes
Abstract:
Antisense oligonucleotides (ASOs) have emerged as one of the most innovative new genetic drug modalities. However, their high...
Delivery Method:
antibody-linked
Organism or Cell Type:
mice
Citation Extract:
Hammond SM, Abendroth F, Goli L, Stoodley J, Burrell M, Thom G, Gurrell I, Ahlskog N, Gait MJ, Wood MJ, Webster CI. Antibody-oligonucleotide conjugate achieves central nervous system delivery in animal models for spinal muscular atrophy. JCI Insight. 2022 Nov 8:e154142. doi: 10.1172/jci.insight.154142. Online ahead of print.

Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR

Authors:
Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK
Citation:
Nat Commun. 2022 Nov 5;13(1):6681. doi: 10.1038/s41467-022-34363-w
Epub:
Not Epub
Abstract:
Transitioning from pluripotency to differentiated cell fates is fundamental to both embryonic development and adult tissue...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK. Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. Nat Commun. 2022 Nov 5;13(1):6681. doi: 10.1038/s41467-022-34363-w.

Awakening adult neural stem cells: NOX signalling as a positive regulator of quiescence to proliferation transition in the Xenopus retina

Authors:
Donval A, Puente CVH, Lainé A, Roman D, Vessely R, Leclercq J, Perron M, Locker M
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.06.515333
Epub:
Not Epub
Abstract:
Reactive oxygen species (ROS) are both harmful molecules sustaining the pathogenesis of several diseases and essential...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Donval A, Puente CVH, Lainé A, Roman D, Vessely R, Leclercq J, Perron M, Locker M. Awakening adult neural stem cells: NOX signalling as a positive regulator of quiescence to proliferation transition in the Xenopus retina. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.06.515333.

Mapping the convergence of genes for coronary artery disease onto endothelial cell programs

Authors:
Schnitzler GR, Kang H, Lee-Kim VS, Ma XR, Zeng T, Angom RS, Fang S, Vellarikkal SK, Zhou R, Guo K, Sias-Garcia O, Bloemendal A, Glen Munson, Guckelberger P, Nguyen TH, Bergman DT, Cheng N, Cleary B, Aragam K, Mukhopadhyay D, Lander ES, Finucane HK, Gupta RM, Engreitz JM
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.01.514606
Epub:
Not Epub
Abstract:
Genome-wide association studies (GWAS) have discovered thousands of risk loci for common, complex diseases, each of which could...
Organism or Cell Type:
zebrafish
Citation Extract:
Schnitzler GR, Kang H, Lee-Kim VS, Ma XR, Zeng T, Angom RS, Fang S, Vellarikkal SK, Zhou R, Guo K, Sias-Garcia O, Bloemendal A, Glen Munson, Guckelberger P, Nguyen TH, Bergman DT, Cheng N, Cleary B, Aragam K, Mukhopadhyay D, Lander ES, Finucane HK, Gupta RM, Engreitz JM. Mapping the convergence of genes for coronary artery disease onto endothelial cell programs. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.01.514606.

Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis

Authors:
Rosa JB, Nassman KY, Sagasti A
Citation:
Mol Biol Cell. 2022;[Epub ahead of print] doi:10.1091/mbc.E22-09-0396
Epub:
Not Epub
Abstract:
Epithelial cell properties are determined by the polarized distribution of membrane lipids, the cytoskeleton, and adhesive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rosa JB, Nassman KY, Sagasti A. Sensory axons induce epithelial lipid microdomain remodeling and determine the distribution of junctions in the epidermis. Mol Biol Cell. 2022;[Epub ahead of print] doi:10.1091/mbc.E22-09-0396.

Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo

Authors:
Truszkowski L, Batur D, Long H, Tarbashevich K, Vos BE, Trappmann B, Raz E
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.11.02.514858
Epub:
Not Epub
Abstract:
In both physiological processes and disease contexts, migrating cells have the ability to adapt to conditions in their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Truszkowski L, Batur D, Long H, Tarbashevich K, Vos BE, Trappmann B, Raz E. Primordial germ cells adjust their protrusion type while migrating in different tissue contexts in vivo. bioRxiv. 2022;[preprint] doi:10.1101/2022.11.02.514858.

Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development

Authors:
Aljiboury AA, Ingram E, Krishnan N, Ononiwu F, Pal D, Manikas J, Taveras C, Hall NA, Da Silva J, Freshour J, Hehnly H
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.31.514532
Epub:
Not Epub
Abstract:
An essential process for cilia formation during epithelialization is the movement of the centrosome to dock with the cell’s...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aljiboury AA, Ingram E, Krishnan N, Ononiwu F, Pal D, Manikas J, Taveras C, Hall NA, Da Silva J, Freshour J, Hehnly H. Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.31.514532.

Tamalin Function Is Required for the Survival of Neurons and Oligodendrocytes in the CNS

Authors:
Seo Y, Mo S, Kim S, Kim H, Park H-C
Citation:
Int J Mol Sci. 2022. 23:13395. doi:10.3390/ijms232113395
Epub:
Not Epub
Abstract:
Tamalin is a post-synaptic scaffolding protein that interacts with group 1 metabotropic glutamate receptors (mGluRs) and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seo Y, Mo S, Kim S, Kim H, Park H-C. Tamalin Function Is Required for the Survival of Neurons and Oligodendrocytes in the CNS. Int J Mol Sci. 2022. 23:13395. doi:10.3390/ijms232113395.

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