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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
The microbiota promotes social behavior by modulating microglial remodeling of forebrain neurons
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Citation:
PLoS Biol. 2022;20(11):e3001838. doi:10.1371/journal.pbio.3001838 Epub:
Not Epub Abstract:
Host-associated microbiotas guide the trajectory of developmental programs, and altered microbiota composition is linked to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bruckner JJ, Stednitz SJ, Grice MZ, Zaidan D, Massaquoi MS, Larsch J, Tallafuss A, Guillemin K, Washbourne P, Eisen JS. The microbiota promotes social behavior by modulating microglial remodeling of forebrain neurons. PLoS Biol. 2022;20(11):e3001838. doi:10.1371/journal.pbio.3001838. |
Artificial Control of the Prunus Self-incompatibility System Using Antisense Oligonucleotides Against Pollen Genes
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Citation:
Hort J. 2022;91(4):437-47. doi:10.2503/hortj.QH-002 Epub:
Not Epub Abstract:
Prunus (Rosaceae) includes many commercially important fruit crop species that exhibit self-incompatibility (SI), including... Delivery Method:
pollen bathing Organism or Cell Type:
Prunus sp. pollen Citation Extract: Ono K, Masui K, Tao R. Artificial Control of the Prunus Self-incompatibility System Using Antisense Oligonucleotides Against Pollen Genes. Hort J. 2022;91(4):437-47. doi:10.2503/hortj.QH-002. |
ASO targeting temperature-controlled RBM3 poison exon splicing prevents neurodegeneration in vivo
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.26.513170 Epub:
Not Epub Abstract:
Neurodegenerative diseases become increasingly prevalent in the aging population and currently no cure is available. Increasing... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: HEK293 Citation Extract: Preußner M, Smith HL, Zhang M, Hughes D, Emmerichs A-K, Scalzitti S, Peretti D, Swinden D, Neumann A, Haltenhof T, Mallucci GR, Heyd F
. ASO targeting temperature-controlled RBM3 poison exon splicing prevents neurodegeneration in vivo. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.26.513170. |
Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia
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Citation:
Case Rep Neurol. 2022;14:404-7. doi:10.1159/000527358 Epub:
Not Epub Abstract:
Eteplirsen is an antisense oligonucleotide used in the treatment of Duchenne muscular dys-
trophy (DMD). The safety of... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Aiello GM, Cartwright MS. Eteplirsen Use in a Boy with Duchenne Muscular Dystrophy and Sickle Cell Anemia. Case Rep Neurol. 2022;14:404-7. doi:10.1159/000527358. |
Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling
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Citation:
Environ Pollut. 2022 Oct 25:120510. doi: 10.1016/j.envpol.2022.120510. Online ahead of print Epub:
Yes Abstract:
Polycyclic aromatic hydrocarbons (PAHs) and pesticides are two major groups of environmental contaminants which humans are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Endirlik B Ü, E Wincent, K Dreij. Non-additive mixture effects of benzo[a]pyrene and pesticides in vitro and in vivo: Role of AhR signaling. Environ Pollut. 2022 Oct 25:120510. doi: 10.1016/j.envpol.2022.120510. Online ahead of print. |
The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease
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Citation:
Metabolites. 2022 Oct 20;12(10):999. doi: 10.3390/metabo12100999 Epub:
Not Epub Abstract:
Cyclosporine A (CSA) is an immunosuppressive drug that has improved transplant survival rates. However, its use is often... Delivery Method:
i.v. injection Organism or Cell Type:
mice Citation Extract: Marghani BH, El-Adl M, Ateya AI, Othman BH, Ghamry HI, Shukry M, Soliman MM, Rizk MA. The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease. Metabolites. 2022 Oct 20;12(10):999. doi: 10.3390/metabo12100999. |
Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming
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Citation:
Nat Phys. 2022;[Epub ahead of print] doi:10.1038/s41567-022-01787-6 Epub:
Yes Abstract:
Embryo development requires biochemical signalling to generate patterns of cell fates and active mechanical forces to drive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pinheiro D, Kardos R, Hannezo É, Heisenberg C-P. Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming. Nat Phys. 2022;[Epub ahead of print] doi:10.1038/s41567-022-01787-6. |
Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis
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Citation:
Data Brief. 2018 Jan 17;17:559-563. doi:10.1016/j.dib.2018.01.005. eCollection 2018 Apr Epub:
Not Epub Abstract:
The transcription factors GATA4, GATA5 and GATA6 play important roles in heart muscle differentiation. The data presented in... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Afouda BA, Lynch AT, de Paiva Alves E, Hoppler S. Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis. Data Brief. 2018 Jan 17;17:559-563. doi:10.1016/j.dib.2018.01.005. eCollection 2018 Apr. |
Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions
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Citation:
BMC Genomics. 2022;23:723. doi:10.1186/s12864-022-08953-3 Epub:
Not Epub Abstract:
Background: During embryogenesis, the developmental potential of initially pluripotent cells becomes progressively restricted... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Johnson K, Freedman S, Braun R, LaBonne C. Quantitative analysis of transcriptome dynamics provides novel insights into developmental state transitions. BMC Genomics. 2022;23:723. doi:10.1186/s12864-022-08953-3. |
Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336 Epub:
Not Epub Abstract:
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Li Y, Xu J, Cui Y, Wu Q, Yin H, Li Y, Jiang L, Wang H, Wen Z, Yao Z, Wu Z. Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.22.513336. |