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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy
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Citation:
Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print Epub:
Yes Abstract:
Purpose: Antisense oligonucleotide (ASO) therapeutics are an emerging class of biopharmaceuticals to treat and prevent diseases... Citation Extract: Becette OB, Marino JP, Brinson RG. Structural Fingerprinting of Antisense Oligonucleotide Therapeutics by Solution NMR Spectroscopy. Pharm Res. 2022 Oct 4. doi: 10.1007/s11095-022-03403-x. Online ahead of print. |
Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development
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Citation:
J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042 Epub:
Not Epub Abstract:
Most cases of Stickler syndrome are due to autosomal-dominant COL2A1 gene mutations leading to abnormal type II collagen.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Williams AL, Bohnsack BL. Zebrafish Model of Stickler Syndrome Suggests a Role for Col2a1a in the Neural Crest during Early Eye Development. J Dev Biol 2022;10(4):42. doi:10.3390/jdb10040042. |
An FGF Timer for Zygotic Genome Activation
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450 Epub:
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Zygotic genome activation has been extensively studied in a variety of systems including flies, frogs, and mammals. However,... Delivery Method:
microinjection Organism or Cell Type:
Ciona intestinalis (ascidian) Citation Extract: Treen N, Chavarria E, Weaver CJ, Brangwynne CF, Levine M. An FGF Timer for Zygotic Genome Activation. bioRxiv. 2022;[preprint] doi:10.1101/2022.10.01.510450. |
RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification
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Citation:
Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600 Epub:
Not Epub Abstract:
While neural crest development is known to be transcriptionally controlled via sequential activation of gene regulatory... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600. |
Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos
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Citation:
Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print Epub:
Yes Abstract:
Background: Molecular networks associated with dopaminergic (DA) neurogenesis remain undefined within mammalian models. To... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kumar A, Rhee M. Transcriptomic networks of gba3 governing specification of the dopaminergic neurons in zebrafish embryos. Genes Genomics. 2022 Oct 1. doi: 10.1007/s13258-022-01317-x. Online ahead of print. |
Cyclin B3 implements timely vertebrate oocyte arrest for fertilization
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Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005 Epub:
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To ensure successful offspring ploidy, vertebrate oocytes must halt the cell cycle in meiosis II until sperm entry. Emi2 is... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Bouftas N, Schneider L, Halder M, Demmig R, Baack M, Cladière D, Walter M, Al Abdallah H, Kleinhempel C, Messaritaki R, Müller J, Passarelli F, Wehrle P, Heim A, Wassmann K, Mayer TU. Cyclin B3 implements timely vertebrate oocyte arrest for fertilization. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.005. |
Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells
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Citation:
Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006 Epub:
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Yamanaka factors are essential for establishing pluripotency in embryonic stem cells, but their function in multipotent stem... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hovland AS, Bhattacharya D, Azambuja AP, Pramio D, Copeland J, Rothstein M, Simoes-Costa M. Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells. Dev Cell. 2022;[Epub ahead of print] doi:10.1016/j.devcel.2022.09.006. |
Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo
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Citation:
Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print Epub:
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The vertebrate body is organized along the dorsal-ventral (DV) and anterior-posterior (AP) axes by the BMP and Wnt pathways,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Takebayashi-Suzuki K, Uchida M, Suzuki A. Zbtb21 is required for the anterior-posterior patterning of neural tissue in the early Xenopus embryo. Biochem Biophys Res Commun. 2022 Sep 15;630:190-197. doi: 10.1016/j.bbrc.2022.09.048. Online ahead of print. |
Transcription factors interact with RNA to regulate genes
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Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.27.509776 Epub:
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Transcription factors (TFs) orchestrate the gene expression programs that define each cell's identity. The canonical TF... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Oksuz O, Henninger JE, Warneford-Thomson W, Zheng MM, Erb H, Overholt KJ, Hawken SW, Banani SF, Lauman R, Vancura A, Robertson AL, Hannett NM, Lee T, Zon LI, Bonasio R, Young RA. Transcription factors interact with RNA to regulate genes. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.27.509776. |
eIF4B mRNA Translation Contributes to Cleavage Dynamics in Early Sea Urchin Embryos
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Citation:
Biology. 2022;11(10):1408. doi:10.3390/biology11101408 Epub:
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During the first steps of sea urchin development, fertilization elicits a marked increase in protein synthesis essential for... Delivery Method:
microinjection Organism or Cell Type:
Paracentrotus lividus, Sphaerechinus granularis (sea urchins) Citation Extract: Pontheaux F, Boulben S, Chassé H, Boutet A, Roch F, Morales J, Cormier P. eIF4B mRNA Translation Contributes to Cleavage Dynamics in Early Sea Urchin Embryos. Biology. 2022;11(10):1408. doi:10.3390/biology11101408 . |