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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models

Authors:
Cafora M, Poerio N, Forti F, Loberto N, Pin D, Bassi R, Aureli M, Briani F, Pistocchi A, Fraziano M
Citation:
Front Microbiol. 2022;13:979610. doi:10.3389/fmicb.2022.979610
Epub:
Not Epub
Abstract:
Multi drug resistant (MDR) bacteria are insensitive to the most common antibiotics currently in use. The spread of antibiotic-...
Link:
https://www.frontiersin.org/articles/10.3389/fmicb.2022.979610/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Poerio N, Forti F, Loberto N, Pin D, Bassi R, Aureli M, Briani F, Pistocchi A, Fraziano M. Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models. Front Microbiol. 2022;13:979610. doi:10.3389/fmicb.2022.979610.

A self-generated Toddler gradient guides mesodermal cell migration

Authors:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A
Citation:
Sci Adv. 2022 Sep 16;8(37):eadd2488. doi: 10.1126/sciadv.add2488. Epub 2022 Sep 14
Epub:
Not Epub
Abstract:
The sculpting of germ layers during gastrulation relies on the coordinated migration of progenitor cells, yet the cues...
Link:
https://www.science.org/doi/10.1126/sciadv.add2488
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A. A self-generated Toddler gradient guides mesodermal cell migration. Sci Adv. 2022 Sep 16;8(37):eadd2488. doi: 10.1126/sciadv.add2488. Epub 2022 Sep 14.

Effects of pharmacological and genetic manipulation of glucocorticoids during early development of the zebrafish embryo

Authors:
Wilson K, Matrone G, Tucker C, Hadoke P, Kenyon C, Mullins J, Denvir M
Citation:
Endocrine Abstracts. 2013;32:P336 doi:10.1530/endoabs.32.P336
Epub:
Not Epub
Abstract:
Background: The effects of glucocorticoids (GC) on the developing zebrafish embryo (Zfe) are poorly characterised. We have...
Link:
https://www.endocrine-abstracts.org/ea/0032/ea0032p336
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson K, Matrone G, Tucker C, Hadoke P, Kenyon C, Mullins J, Denvir M. Effects of pharmacological and genetic manipulation of glucocorticoids during early development of the zebrafish embryo. Endocrine Abstracts. 2013;32:P336 doi:10.1530/endoabs.32.P336.

Selenoprotein deficiency disorder predisposes to aortic aneurysm formation

Authors:
Schoenmakers E, Marelli F, Jørgensen H, Visser WE, Moran C, Groeneweg S, Avalos C, Figg N, Finigan A, Wali N, Agostini M, Wardle-Jones H, Lyons G, Rusk R, Gopalan D, Visser JJ, Goddard M, Nashef S, Heijmen R, Clift P, Sinha S, Busch-Nentwich E, Ramirez-Solis R, Persani L, Bennett M, Chatterjee K
Citation:
Endocrine Abstracts. 2022;84;OP01-04 doi:10.1530/endoabs.84.OP-01-04
Epub:
Not Epub
Abstract:
Objectives: Mutations in SECISBP2 cause deficiency of selenoproteins, resulting in a multisystem disorder with abnormal...
Link:
https://www.endocrine-abstracts.org/ea/0084/ea0084op-01-04
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schoenmakers E, Marelli F, Jørgensen H, Visser WE, Moran C, Groeneweg S, Avalos C, Figg N, Finigan A, Wali N, Agostini M, Wardle-Jones H, Lyons G, Rusk R, Gopalan D, Visser JJ, Goddard M, Nashef S, Heijmen R, Clift P, Sinha S, Busch-Nentwich E, Ramirez-Solis R, Persani L, Bennett M, Chatterjee K. Selenoprotein deficiency disorder predisposes to aortic aneurysm formation. Endocrine Abstracts. 2022;84;OP01-04 doi:10.1530/endoabs.84.OP-01-04.

The Nanog epigenetic remodeling complex was essential to vertebrate mesoderm evolution

Authors:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.08.507069
Epub:
Not Epub
Abstract:
Pluripotency defines the unlimited potential of cells in the primitive ectoderm of vertebrate embryos, from which all adult...
Link:
https://www.biorxiv.org/content/10.1101/2022.09.08.507069v1
Delivery Method:
microinjection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Simpson LA, Crowley D, Forey T, Acosta H, Ferjentsik Z, Chatfield J, Payne A, Simpson BS, Redwood C, Dixon JE, Holmes N, Sang F, Alberio R, Loose M, Johnson AD. The Nanog epigenetic remodeling complex was essential to vertebrate mesoderm evolution. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.08.507069 .

The RhoGEF protein Plekhg5 regulates medioapical actomyosin dynamics of apical constriction during Xenopus gastrulation

Authors:
Baldwin AT, Popov IK, Keller R, Wallingford JB, Chang C
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506049
Epub:
Not Epub
Abstract:
Apical constriction results in apical surface reduction in epithelial cells and is a widely used mechanism for epithelial...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.506049v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Baldwin AT, Popov IK, Keller R, Wallingford JB, Chang C. The RhoGEF protein Plekhg5 regulates medioapical actomyosin dynamics of apical constriction during Xenopus gastrulation. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506049 .

Activation of ERK by altered RNA splicing in cancer

Authors:
Zhang Y, Siraj MA, Chakraborty P, Tseng R, Ku L-T, Das S, Dey A, Dwivedi SKD, Rao G, Zhang M, Yang D, Hossen MN, Ding W-Q, Fung K-M, Bhattacharya R, Escobar-Hoyos L, Mukherjee P
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.505957
Epub:
Not Epub
Abstract:
Many cancers carry change-of-function mutations affecting RNA splicing factors, however, less is known about the functional...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.505957v1
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: Panc1, AsPc1
Citation Extract:
Zhang Y, Siraj MA, Chakraborty P, Tseng R, Ku L-T, Das S, Dey A, Dwivedi SKD, Rao G, Zhang M, Yang D, Hossen MN, Ding W-Q, Fung K-M, Bhattacharya R, Escobar-Hoyos L, Mukherjee P. Activation of ERK by altered RNA splicing in cancer. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.505957.

RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD

Authors:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L
Citation:
Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006
Epub:
Not Epub
Abstract:
BACKGROUND: Many psychiatric disorders share working memory (WM) impairment phenotype, yet the genetic causes remain unclear....
Link:
https://www.bpsgos.org/article/S2667-1743(22)00099-4/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Y, Zhang N, Zhao F, Chang S, Chen W, Cao Q, Sun L, Wang Y, Gong Z, Lu L, Liu D, Yang L. RBFOX1 and working memory: from genome to transcriptome revealed post-transcriptional mechanism separate from ADHD. Biol Psychiatry. 2022;[Epub ahead of print] doi:10.1016/j.bpsgos.2022.08.006.

Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches

Authors:
Bina P, Taneyhill LA
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039
Epub:
Not Epub
Abstract:
The trigeminal ganglion contains the cell bodies of sensory neurons comprising cranial nerve V, which relays information...
Link:
https://www.biorxiv.org/content/10.1101/2022.08.31.506039v1
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Bina P, Taneyhill LA. Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches. bioRxiv. 2022;[preprint] doi:10.1101/2022.08.31.506039 .

A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly

Authors:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P
Citation:
Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727
Epub:
Not Epub
Abstract:
Microcephaly presents in neurodevelopmental disorders with multiple aetiologies, including bi-allelic mutation in TUBGCP2, a...
Link:
https://www.mdpi.com/2073-4409/11/17/2727
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bartoszewski S, Dawidziuk M, Kasica N, Durak R, Jurek M, Podwysocka A, Guilbride DL, Podlasz P, Winata CL, Gawlinski P. A Zebrafish/Drosophila Dual System Model for Investigating Human Microcephaly. Cells. 2022 Sep 1;11(17):2727. doi: 10.3390/cells11172727.

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